ID A0A2K6E6G2_MACNE Unreviewed; 332 AA.
AC A0A2K6E6G2;
DT 28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT 28-MAR-2018, sequence version 1.
DT 24-JAN-2024, entry version 26.
DE RecName: Full=Potassium channel subfamily K member {ECO:0000256|PIRNR:PIRNR038061};
GN Name=KCNK17 {ECO:0000313|Ensembl:ENSMNEP00000043752.1};
OS Macaca nemestrina (Pig-tailed macaque).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Cercopithecidae; Cercopithecinae; Macaca.
OX NCBI_TaxID=9545 {ECO:0000313|Ensembl:ENSMNEP00000043752.1, ECO:0000313|Proteomes:UP000233120};
RN [1] {ECO:0000313|Ensembl:ENSMNEP00000043752.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141,
CC ECO:0000256|PIRNR:PIRNR038061}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141, ECO:0000256|PIRNR:PIRNR038061}.
CC -!- SIMILARITY: Belongs to the two pore domain potassium channel (TC
CC 1.A.1.8) family. {ECO:0000256|ARBA:ARBA00006666,
CC ECO:0000256|RuleBase:RU003857}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR RefSeq; XP_011727665.1; XM_011729363.1.
DR AlphaFoldDB; A0A2K6E6G2; -.
DR STRING; 9545.ENSMNEP00000043752; -.
DR GlyCosmos; A0A2K6E6G2; 1 site, No reported glycans.
DR Ensembl; ENSMNET00000068260.1; ENSMNEP00000043752.1; ENSMNEG00000044509.1.
DR GeneID; 105474564; -.
DR KEGG; mni:105474564; -.
DR CTD; 89822; -.
DR GeneTree; ENSGT00940000162681; -.
DR OMA; WRQGPDR; -.
DR OrthoDB; 600333at2759; -.
DR Proteomes; UP000233120; Unplaced.
DR Bgee; ENSMNEG00000044509; Expressed in liver and 1 other cell type or tissue.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005267; F:potassium channel activity; IEA:UniProtKB-UniRule.
DR Gene3D; 1.10.287.70; -; 1.
DR InterPro; IPR003280; 2pore_dom_K_chnl.
DR InterPro; IPR003092; 2pore_dom_K_chnl_TASK.
DR InterPro; IPR013099; K_chnl_dom.
DR PANTHER; PTHR11003:SF340; POTASSIUM CHANNEL SUBFAMILY K MEMBER 17; 1.
DR PANTHER; PTHR11003; POTASSIUM CHANNEL, SUBFAMILY K; 1.
DR Pfam; PF07885; Ion_trans_2; 2.
DR PIRSF; PIRSF038061; K_channel_subfamily_K_type; 1.
DR PRINTS; PR01333; 2POREKCHANEL.
DR PRINTS; PR01095; TASKCHANNEL.
DR SUPFAM; SSF81324; Voltage-gated potassium channels; 2.
PE 3: Inferred from homology;
KW Ion channel {ECO:0000256|RuleBase:RU003857};
KW Ion transport {ECO:0000256|PIRNR:PIRNR038061,
KW ECO:0000256|RuleBase:RU003857};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|PIRNR:PIRNR038061};
KW Potassium {ECO:0000256|ARBA:ARBA00022958, ECO:0000256|PIRNR:PIRNR038061};
KW Potassium channel {ECO:0000256|ARBA:ARBA00022826,
KW ECO:0000256|PIRNR:PIRNR038061};
KW Potassium transport {ECO:0000256|ARBA:ARBA00022538,
KW ECO:0000256|PIRNR:PIRNR038061};
KW Reference proteome {ECO:0000313|Proteomes:UP000233120};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU003857};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius};
KW Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|PIRNR:PIRNR038061}.
FT TRANSMEM 23..43
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 128..148
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 178..200
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 212..232
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 244..264
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 95..156
FT /note="Potassium channel"
FT /evidence="ECO:0000259|Pfam:PF07885"
FT DOMAIN 193..267
FT /note="Potassium channel"
FT /evidence="ECO:0000259|Pfam:PF07885"
FT CARBOHYD 94
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000256|PIRSR:PIRSR038061-1"
SQ SEQUENCE 332 AA; 37060 MW; F0FE8D88BF44CACC CRC64;
MYRPRTRAGP EDRGWGCAVP STVLLLFAYL AYLALGTGVF WTLEGRAAQE SSRSFQRDKW
ELLQNFTCLD RPALDSLIRD VVQAYKNGAS LLSNTTGMGR WELLGSFFFS VSTITTIGYG
NLSPNTMAAR LFCIFFALVG IPLNLVVLNR LGHLMQQGVN HCSSRLGGTW QDPGKARWLA
GSGALLSGLL LFLLLPPLLF SHMEGWSYME GFYFAFITLS TVGFGDYVIG MNPSRRYPLW
YKNVVSLWIL FGMAWLALII KLILSQLETP GRVCSCYHRS SKEDFKSQSW RLGPNREPEA
HSPQQECYPE GPMGIVRHLE PSAQAAGCCK DS
//
