ID A0A2K6E6Y2_MACNE Unreviewed; 420 AA.
AC A0A2K6E6Y2;
DT 28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT 28-MAR-2018, sequence version 1.
DT 24-JAN-2024, entry version 32.
DE RecName: Full=Transcriptional adapter {ECO:0000256|PIRNR:PIRNR025024};
GN Name=TADA2B {ECO:0000313|Ensembl:ENSMNEP00000043919.1};
OS Macaca nemestrina (Pig-tailed macaque).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Cercopithecidae; Cercopithecinae; Macaca.
OX NCBI_TaxID=9545 {ECO:0000313|Ensembl:ENSMNEP00000043919.1, ECO:0000313|Proteomes:UP000233120};
RN [1] {ECO:0000313|Ensembl:ENSMNEP00000043919.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123,
CC ECO:0000256|PIRNR:PIRNR025024}.
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DR RefSeq; XP_011743272.1; XM_011744970.1.
DR AlphaFoldDB; A0A2K6E6Y2; -.
DR STRING; 9545.ENSMNEP00000043919; -.
DR Ensembl; ENSMNET00000068427.1; ENSMNEP00000043919.1; ENSMNEG00000044586.1.
DR GeneID; 105483899; -.
DR KEGG; mni:105483899; -.
DR CTD; 93624; -.
DR GeneTree; ENSGT00940000157318; -.
DR OMA; IELCPDC; -.
DR OrthoDB; 206414at2759; -.
DR Proteomes; UP000233120; Unplaced.
DR Bgee; ENSMNEG00000044586; Expressed in skeletal muscle tissue and 12 other cell types or tissues.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0000124; C:SAGA complex; IEA:Ensembl.
DR GO; GO:0003713; F:transcription coactivator activity; IEA:InterPro.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR GO; GO:0035065; P:regulation of histone acetylation; IEA:InterPro.
DR GO; GO:0006357; P:regulation of transcription by RNA polymerase II; IEA:InterPro.
DR CDD; cd00167; SANT; 1.
DR CDD; cd02335; ZZ_ADA2; 1.
DR Gene3D; 3.30.60.90; -; 1.
DR Gene3D; 1.10.10.60; Homeodomain-like; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR041983; ADA2-like_ZZ.
DR InterPro; IPR016827; Ada2/TADA2.
DR InterPro; IPR009057; Homeobox-like_sf.
DR InterPro; IPR001005; SANT/Myb.
DR InterPro; IPR017884; SANT_dom.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR000433; Znf_ZZ.
DR InterPro; IPR043145; Znf_ZZ_sf.
DR PANTHER; PTHR12374:SF63; TRANSCRIPTIONAL ADAPTER 2-BETA; 1.
DR PANTHER; PTHR12374; TRANSCRIPTIONAL ADAPTOR 2 ADA2 -RELATED; 1.
DR Pfam; PF00249; Myb_DNA-binding; 1.
DR PIRSF; PIRSF025024; Transcriptional_adaptor_2; 2.
DR SMART; SM00717; SANT; 1.
DR SMART; SM00291; ZnF_ZZ; 1.
DR SUPFAM; SSF46689; Homeodomain-like; 2.
DR SUPFAM; SSF57850; RING/U-box; 1.
DR PROSITE; PS50090; MYB_LIKE; 1.
DR PROSITE; PS51293; SANT; 1.
DR PROSITE; PS01357; ZF_ZZ_1; 1.
DR PROSITE; PS50135; ZF_ZZ_2; 1.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|PIRNR:PIRNR025024};
KW Reference proteome {ECO:0000313|Proteomes:UP000233120};
KW Transcription {ECO:0000256|ARBA:ARBA00023163,
KW ECO:0000256|PIRNR:PIRNR025024};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015,
KW ECO:0000256|PIRNR:PIRNR025024}; Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00228}.
FT DOMAIN 4..59
FT /note="ZZ-type"
FT /evidence="ECO:0000259|PROSITE:PS50135"
FT DOMAIN 65..118
FT /note="SANT"
FT /evidence="ECO:0000259|PROSITE:PS51293"
FT DOMAIN 67..114
FT /note="Myb-like"
FT /evidence="ECO:0000259|PROSITE:PS50090"
FT REGION 305..335
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 420 AA; 48440 MW; 9C97364BE8C5847C CRC64;
MAELGKKYCV YCLAEVSPLR FRCTECQDIE LCPECFSAGA EIGHHRRYHG YQLVDGGRFT
LWGPEAEGGW TSREEQLLLD AIEQFGFGNW EDMAAHVGAS RTPQEVMEHY VSMYIHGNLG
KACIPDTIPN RVTDHTCPSG GPLSPSLTTP LPPLDISVAE QQQLGYMPLR DDYEIEYDQD
AETLISGLSV NYDDDDVEIE LKRAHVDMYV RKLKERQRRK NIARDYNLVP AFLGKDKKEK
EKALKRKITK EEKELRLKLR PLYQFMSCKE FDDLFENMHK EKMLRAKIRE LQRYRRNGIT
KMEESAEYEA ARHKREKRKE NKNLAGSKRG KEDGKDGEFA AIENLPGFEL LSDREKVLCS
SLNLSPARYV TVKTIIIKDH LQKRQGIPSK SRLPSYLDKV LKKRILNFLT ESGWISRDAS
//
