ID A0A2K6EAJ1_MACNE Unreviewed; 609 AA.
AC A0A2K6EAJ1;
DT 28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT 28-MAR-2018, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE SubName: Full=Zinc finger protein X-linked {ECO:0000313|Ensembl:ENSMNEP00000045183.1};
GN Name=ZFX {ECO:0000313|Ensembl:ENSMNEP00000045183.1};
OS Macaca nemestrina (Pig-tailed macaque).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Cercopithecidae; Cercopithecinae; Macaca.
OX NCBI_TaxID=9545 {ECO:0000313|Ensembl:ENSMNEP00000045183.1, ECO:0000313|Proteomes:UP000233120};
RN [1] {ECO:0000313|Ensembl:ENSMNEP00000045183.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
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DR AlphaFoldDB; A0A2K6EAJ1; -.
DR Ensembl; ENSMNET00000069694.1; ENSMNEP00000045183.1; ENSMNEG00000045098.1.
DR GeneTree; ENSGT00940000158684; -.
DR Proteomes; UP000233120; Unplaced.
DR Bgee; ENSMNEG00000045098; Expressed in thymus and 12 other cell types or tissues.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR Gene3D; 3.30.160.60; Classic Zinc Finger; 8.
DR InterPro; IPR006794; Transcrp_activ_Zfx/Zfy-dom.
DR InterPro; IPR036236; Znf_C2H2_sf.
DR InterPro; IPR013087; Znf_C2H2_type.
DR PANTHER; PTHR24381:SF393; CHROMATIN-LINKED ADAPTOR FOR MSL PROTEINS, ISOFORM B-RELATED; 1.
DR PANTHER; PTHR24381; ZINC FINGER PROTEIN; 1.
DR Pfam; PF00096; zf-C2H2; 7.
DR Pfam; PF13909; zf-H2C2_5; 1.
DR Pfam; PF04704; Zfx_Zfy_act; 1.
DR SMART; SM00355; ZnF_C2H2; 13.
DR SUPFAM; SSF57667; beta-beta-alpha zinc fingers; 7.
DR PROSITE; PS00028; ZINC_FINGER_C2H2_1; 7.
DR PROSITE; PS50157; ZINC_FINGER_C2H2_2; 13.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000233120};
KW Zinc {ECO:0000256|PROSITE-ProRule:PRU00042};
KW Zinc-finger {ECO:0000256|PROSITE-ProRule:PRU00042}.
FT DOMAIN 229..259
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 260..282
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 292..319
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 323..351
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 352..379
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 380..408
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 409..436
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 437..465
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 466..493
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 494..522
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 523..550
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 551..579
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 580..607
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
SQ SEQUENCE 609 AA; 69629 MW; E77211495BD31176 CRC64;
MDEDGLELQQ EPNSFFDATV DDAGKIEHDG SSGMTMDTES EIDPCKVDGT CPEVIKVYIF
KADPGEDDLG GTVDIVESEP ENDHGVELLD QNSSIRVPRE KMVYMTVNDS QPEDEDLNVA
EIADEVYMEV IVGEEDAAAA AAAAAVHEQQ MDDNEIKTFM PIAWAAAYGN NSDGIENRNG
TASALLHIDE SAGLGRLAKQ KPKKRRRPDS RQYQTAIIIG PDGHPLTVYP CMICGKKFKS
RGFLKRHMKN HPEHLAKKKY RCTDCDYTTN KKISLHNHLE SHKLTSKAEK AIECDECGKH
FSHAGALFTH KMVHKEKGAN KMHKCKFCEY ETAEQGLLNR HLLAVHSKNF PHICVECGKG
FRHPSELKKH MRIHTGEKPY QCQYCEYRSA DSSNLKTHVK TKHSKEMPFK CDICLLTFSD
TKEVQQHALI HQESKTHQCL HCDHKSSNSS DLKRHIISVH TKDYPHKCDM CDKGFHRPSE
LKKHVAAHKG KKMHQCRHCD FKIADPFVLS RHILSVHTKD LPFRCKRCRK GFRQQNELKK
HMKTHSGRKV YQCEYCEYST TDASGFKRHV ISIHTKDYPH RCEYCKKGFR RPSEKNQHIM
RHHKEVGLP
//
