ID A0A2K6EC40_MACNE Unreviewed; 450 AA.
AC A0A2K6EC40;
DT 28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT 28-MAR-2018, sequence version 1.
DT 27-MAR-2024, entry version 28.
DE RecName: Full=Kelch domain-containing protein 10 {ECO:0000256|ARBA:ARBA00041041};
GN Name=KLHDC10 {ECO:0000313|Ensembl:ENSMNEP00000045732.1};
OS Macaca nemestrina (Pig-tailed macaque).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Cercopithecidae; Cercopithecinae; Macaca.
OX NCBI_TaxID=9545 {ECO:0000313|Ensembl:ENSMNEP00000045732.1, ECO:0000313|Proteomes:UP000233120};
RN [1] {ECO:0000313|Ensembl:ENSMNEP00000045732.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the KLHDC10 family.
CC {ECO:0000256|ARBA:ARBA00038487}.
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DR RefSeq; XP_011722172.1; XM_011723870.1.
DR AlphaFoldDB; A0A2K6EC40; -.
DR SMR; A0A2K6EC40; -.
DR STRING; 9545.ENSMNEP00000045732; -.
DR Ensembl; ENSMNET00000070245.1; ENSMNEP00000045732.1; ENSMNEG00000045353.1.
DR GeneID; 105471398; -.
DR KEGG; mni:105471398; -.
DR CTD; 23008; -.
DR GeneTree; ENSGT00940000155977; -.
DR OrthoDB; 2882436at2759; -.
DR Proteomes; UP000233120; Unplaced.
DR Bgee; ENSMNEG00000045353; Expressed in pituitary gland and 12 other cell types or tissues.
DR GO; GO:0031462; C:Cul2-RING ubiquitin ligase complex; IEA:Ensembl.
DR GO; GO:0005737; C:cytoplasm; IEA:Ensembl.
DR GO; GO:0005654; C:nucleoplasm; IEA:Ensembl.
DR GO; GO:1990756; F:ubiquitin ligase-substrate adaptor activity; IEA:Ensembl.
DR GO; GO:0072344; P:rescue of stalled ribosome; IEA:Ensembl.
DR GO; GO:0140627; P:ubiquitin-dependent protein catabolic process via the C-end degron rule pathway; IEA:Ensembl.
DR Gene3D; 2.120.10.80; Kelch-type beta propeller; 2.
DR InterPro; IPR015915; Kelch-typ_b-propeller.
DR InterPro; IPR006652; Kelch_1.
DR PANTHER; PTHR46428; KELCH DOMAIN-CONTAINING PROTEIN 10; 1.
DR PANTHER; PTHR46428:SF1; KELCH DOMAIN-CONTAINING PROTEIN 10; 1.
DR Pfam; PF01344; Kelch_1; 1.
DR Pfam; PF13418; Kelch_4; 1.
DR Pfam; PF13854; Kelch_5; 1.
DR Pfam; PF13964; Kelch_6; 1.
DR SMART; SM00612; Kelch; 2.
DR SUPFAM; SSF117281; Kelch motif; 1.
DR SUPFAM; SSF101898; NHL repeat; 1.
PE 3: Inferred from homology;
KW Kelch repeat {ECO:0000256|ARBA:ARBA00022441};
KW Reference proteome {ECO:0000313|Proteomes:UP000233120};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT REGION 1..57
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 450 AA; 49953 MW; 3B738267D1B7C5F4 CRC64;
MSAAQGWDRN RRRGGGAAGA GGGGSGAGGG SGGSGGRGTG QLNRFVQLSG RPHLPGKKKI
RWDPVRRRFI QSCPIIRIPN RFLRAHLEVA TSCHRPPPAR SGHRCVADNT NLYVFGGYNP
DYDESGGPDN EDYPLFRELW RYHFATGVWH QMGTDGYMPR ELASMSLVLH GNNLLVFGGT
GIPFGESNGN DVHVCNVKYK RWALLSCRGK KPSRIYGQAM AIINGSLYVF GGTTGYIYST
DLHKLDLNTR EWTQLKPNNL SCDLPEERYR HEIAHDGQRI YILGGGTSWT AYSLNKIHAY
NLETNAWEEI ATKPHEKIGF PAARRCHSCV QIKNDVFICG GYNGEVILGD IWKLNLQTFQ
WVKLPATMPE PVYFHCAAVT PAGCMYIHGG VVNIHENKRT GSLFKIWLVV PSLLELAWEK
LLAAFPNLAN LSRTQLLHLG LTQGLIERLK
//
