ID   A0A2K6EHI2_PROCO        Unreviewed;       337 AA.
AC   A0A2K6EHI2;
DT   28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT   28-MAR-2018, sequence version 1.
DT   24-JAN-2024, entry version 20.
DE   SubName: Full=Islet cell autoantigen 1 {ECO:0000313|Ensembl:ENSPCOP00000001199.1};
GN   Name=ICA1 {ECO:0000313|Ensembl:ENSPCOP00000001199.1};
OS   Propithecus coquereli (Coquerel's sifaka) (Propithecus verreauxi
OS   coquereli).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Strepsirrhini; Lemuriformes;
OC   Indriidae; Propithecus.
OX   NCBI_TaxID=379532 {ECO:0000313|Ensembl:ENSPCOP00000001199.1, ECO:0000313|Proteomes:UP000233160};
RN   [1] {ECO:0000313|Ensembl:ENSPCOP00000001199.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
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DR   AlphaFoldDB; A0A2K6EHI2; -.
DR   Ensembl; ENSPCOT00000004240.1; ENSPCOP00000001199.1; ENSPCOG00000003590.1.
DR   GeneTree; ENSGT00390000005530; -.
DR   Proteomes; UP000233160; Unplaced.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProt.
DR   GO; GO:0012505; C:endomembrane system; IEA:UniProt.
DR   GO; GO:0043231; C:intracellular membrane-bounded organelle; IEA:UniProt.
DR   GO; GO:0019904; F:protein domain specific binding; IEA:InterPro.
DR   CDD; cd07661; BAR_ICA69; 1.
DR   Gene3D; 1.20.1270.60; Arfaptin homology (AH) domain/BAR domain; 1.
DR   InterPro; IPR027267; AH/BAR_dom_sf.
DR   InterPro; IPR010504; AH_dom.
DR   InterPro; IPR024114; Islet_autoAg_Ica1/Ica1-like.
DR   PANTHER; PTHR10164; ISLET CELL AUTOANTIGEN 1; 1.
DR   PANTHER; PTHR10164:SF3; ISLET CELL AUTOANTIGEN 1; 1.
DR   Pfam; PF06456; Arfaptin; 1.
DR   SMART; SM01015; Arfaptin; 1.
DR   SUPFAM; SSF103657; BAR/IMD domain-like; 1.
DR   PROSITE; PS50870; AH; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000233160}.
FT   DOMAIN          51..254
FT                   /note="AH"
FT                   /evidence="ECO:0000259|PROSITE:PS50870"
SQ   SEQUENCE   337 AA;  39299 MW;  81AAE66F12FAC932 CRC64;
     MSGHKCSYSW DLQNRYAQDK SVVNKMQQKY WETKQAFIKA TGKKEDEHVV ASDADLDAKL
     ELFHSIQRTC LDLSKAIVLY QKRICFLSQE ENELGKFLRS QGFQDKTRAG KMMQATGKAL
     CFSSQQRLAL RNPLCRFHQE VETFRHRAIS DTWLTVNRME QCRTEYRGAL LWMKDVSQEL
     DPDLYKQMEK FRKVQSQVRL AKKNFDKLKM DVCQKVDLLG ASRCNLLSHM LATYQTTLLH
     FWEKTSHTMA AIHESFKGYQ PYEFTTLKVK LERLLENLTK SKVLFILSQA KSMAASIIIP
     RLKMPKRELC PQQGLFTVSA FSTMIIHCNP KAQTEPW
//