ID A0A2K6ENZ7_PROCO Unreviewed; 454 AA.
AC A0A2K6ENZ7;
DT 28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT 28-MAR-2018, sequence version 1.
DT 24-JAN-2024, entry version 30.
DE SubName: Full=Mitochondrial elongation factor 2 {ECO:0000313|Ensembl:ENSPCOP00000003460.1};
GN Name=MIEF2 {ECO:0000313|Ensembl:ENSPCOP00000003460.1};
OS Propithecus coquereli (Coquerel's sifaka) (Propithecus verreauxi
OS coquereli).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Strepsirrhini; Lemuriformes;
OC Indriidae; Propithecus.
OX NCBI_TaxID=379532 {ECO:0000313|Ensembl:ENSPCOP00000003460.1, ECO:0000313|Proteomes:UP000233160};
RN [1] {ECO:0000313|Ensembl:ENSPCOP00000003460.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004167}; Single-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004167}. Mitochondrion
CC outer membrane {ECO:0000256|ARBA:ARBA00004572}; Single-pass membrane
CC protein {ECO:0000256|ARBA:ARBA00004572}.
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DR RefSeq; XP_012520424.1; XM_012664970.1.
DR AlphaFoldDB; A0A2K6ENZ7; -.
DR STRING; 379532.ENSPCOP00000003460; -.
DR Ensembl; ENSPCOT00000011806.1; ENSPCOP00000003460.1; ENSPCOG00000010406.1.
DR GeneID; 105826955; -.
DR KEGG; pcoq:105826955; -.
DR CTD; 125170; -.
DR GeneTree; ENSGT00390000013127; -.
DR OMA; LQDWYPA; -.
DR OrthoDB; 2897585at2759; -.
DR Proteomes; UP000233160; Unplaced.
DR GO; GO:0005741; C:mitochondrial outer membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0007005; P:mitochondrion organization; IEA:Ensembl.
DR GO; GO:0090141; P:positive regulation of mitochondrial fission; IEA:Ensembl.
DR GO; GO:0090314; P:positive regulation of protein targeting to membrane; IEA:Ensembl.
DR Gene3D; 1.10.1410.40; -; 1.
DR Gene3D; 3.30.460.90; -; 1.
DR InterPro; IPR024810; Mab-21-like.
DR InterPro; IPR046906; Mab-21_HhH/H2TH-like.
DR InterPro; IPR045909; MID49/MID51.
DR InterPro; IPR049097; MID51-like_C.
DR PANTHER; PTHR16451:SF11; MITOCHONDRIAL DYNAMICS PROTEIN MID49; 1.
DR PANTHER; PTHR16451; MITOCHONDRIAL DYNAMICS PROTEINS 49/51 FAMILY MEMBER; 1.
DR Pfam; PF20266; Mab-21_C; 1.
DR Pfam; PF21297; MID51-like_C; 1.
DR SMART; SM01265; Mab-21; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Mitochondrion {ECO:0000256|ARBA:ARBA00023128};
KW Mitochondrion outer membrane {ECO:0000256|ARBA:ARBA00022787};
KW Reference proteome {ECO:0000313|Proteomes:UP000233160};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 21..47
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 146..338
FT /note="Mitochondrial dynamics protein MID51-like C-
FT terminal"
FT /evidence="ECO:0000259|Pfam:PF21297"
FT DOMAIN 388..439
FT /note="Mab-21-like HhH/H2TH-like"
FT /evidence="ECO:0000259|Pfam:PF20266"
FT REGION 77..115
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 79..115
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 454 AA; 49260 MW; 606462F2D9E913BC CRC64;
MAEFSQKRGK RRGDEGLGSV VDFLLANARL VLGVGGAAVL GIATLAVKRF IDRATSPQDE
DDTKGDSWKE LSLLKATPNL QPRPPPAALS QPVLPQPPLP SAPEGPADTV PHVPPQLSSP
APLCLTFQEK LLAFERAHVT IPAAQVALAK QLAGDIALEL QAYLRSKFPE LPFGALVPQG
PLYDGLQAGA ADHVRLLVPL VLEPGLWSMV PGVDTVARDP RCWAVRRTQL EFHPRGSSPW
DRFLVGGYLS SRVLLELLRK ALAASVNWPA IGSLLGCLIR PSLASEELLL EVQHERLELT
AAVLVAVPGA DADDRLLLAW PLEGLAGNLW LQDLYPVEAA RLRALDDHDS GTRRRLLLML
CGICRGHLAL GRLGLSHLTQ VVLRLGEEDV DWAEEALGER FLQALELLIC SLERASLPCH
FNPCVNLFDS LCEEEIDDIG YALYSGLQAP EVLL
//
