ID   A0A2K6ESS1_PROCO        Unreviewed;       468 AA.
AC   A0A2K6ESS1;
DT   28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT   28-MAR-2018, sequence version 1.
DT   24-JAN-2024, entry version 28.
DE   SubName: Full=DENN domain containing 2D {ECO:0000313|Ensembl:ENSPCOP00000004775.1};
GN   Name=DENND2D {ECO:0000313|Ensembl:ENSPCOP00000004775.1};
OS   Propithecus coquereli (Coquerel's sifaka) (Propithecus verreauxi
OS   coquereli).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Strepsirrhini; Lemuriformes;
OC   Indriidae; Propithecus.
OX   NCBI_TaxID=379532 {ECO:0000313|Ensembl:ENSPCOP00000004775.1, ECO:0000313|Proteomes:UP000233160};
RN   [1] {ECO:0000313|Ensembl:ENSPCOP00000004775.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
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DR   RefSeq; XP_012514484.1; XM_012659030.1.
DR   AlphaFoldDB; A0A2K6ESS1; -.
DR   Ensembl; ENSPCOT00000015085.1; ENSPCOP00000004775.1; ENSPCOG00000013147.1.
DR   GeneID; 105822093; -.
DR   CTD; 79961; -.
DR   GeneTree; ENSGT00950000182931; -.
DR   OMA; CLFKNRV; -.
DR   OrthoDB; 5398783at2759; -.
DR   Proteomes; UP000233160; Unplaced.
DR   GO; GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:UniProtKB-KW.
DR   Gene3D; 3.30.450.200; -; 1.
DR   Gene3D; 3.40.50.11500; -; 1.
DR   InterPro; IPR001194; cDENN_dom.
DR   InterPro; IPR005112; dDENN_dom.
DR   InterPro; IPR043153; DENN_C.
DR   InterPro; IPR037516; Tripartite_DENN.
DR   InterPro; IPR005113; uDENN_dom.
DR   PANTHER; PTHR15288; DENN DOMAIN-CONTAINING PROTEIN 2; 1.
DR   PANTHER; PTHR15288:SF2; DENN DOMAIN-CONTAINING PROTEIN 2D; 1.
DR   Pfam; PF03455; dDENN; 1.
DR   Pfam; PF02141; DENN; 1.
DR   Pfam; PF03456; uDENN; 1.
DR   SMART; SM00801; dDENN; 1.
DR   SMART; SM00799; DENN; 1.
DR   SMART; SM00800; uDENN; 1.
DR   PROSITE; PS50211; DENN; 1.
PE   4: Predicted;
KW   Guanine-nucleotide releasing factor {ECO:0000256|ARBA:ARBA00022658};
KW   Reference proteome {ECO:0000313|Proteomes:UP000233160}.
FT   DOMAIN          52..442
FT                   /note="UDENN"
FT                   /evidence="ECO:0000259|PROSITE:PS50211"
FT   REGION          11..37
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   468 AA;  53147 MW;  BF79695A4C4A402A CRC64;
     MDGLGRRLRA SLRLKRGHGG SPQDNPGEAV KEPERAQEHS LPNFAGGQHF FEYLLVVSLK
     KKRLGDDYEP TITYQFPKRE NLLRGQQEEE ERLLKAIPLF CFPDGNEWAP LTEYPRETFS
     FVLTNVDGSR KIGYCRRLLP AGPGPRLPKV YCIISCIGCF GLFSKILDEV EKRHQISMAV
     IYPFMQGLRE AAFPAPGKTV TLKSFIPDSG TEFISLTRPL DSHLEHVDFS SLLRCLSFEQ
     ILQIFASAVL ERKIIFLAAD LSTLSQCIHA AAALLYPFSW AHTYIPVVPE SLLATVCCPT
     PFMVGVQMRF RQEVMDSPME EVLLVNLCEG TFLLSVGDEK DILPPKLQED ILGSLGRGID
     ELKTSEEINE HVSGPFVQFF VKTVGHYASY IKREANGQGH FQERSFCKAL TSKTKRRFVK
     KFVKTQLFSL FIQEAEKSKN PPAGYFQQKI LEYEEQKKQK KPREKTVR
//