ID   A0A2K6EU79_PROCO        Unreviewed;       580 AA.
AC   A0A2K6EU79;
DT   28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT   28-MAR-2018, sequence version 1.
DT   27-MAR-2024, entry version 33.
DE   SubName: Full=Netrin 3 {ECO:0000313|Ensembl:ENSPCOP00000005258.1};
GN   Name=NTN3 {ECO:0000313|Ensembl:ENSPCOP00000005258.1};
OS   Propithecus coquereli (Coquerel's sifaka) (Propithecus verreauxi
OS   coquereli).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Strepsirrhini; Lemuriformes;
OC   Indriidae; Propithecus.
OX   NCBI_TaxID=379532 {ECO:0000313|Ensembl:ENSPCOP00000005258.1, ECO:0000313|Proteomes:UP000233160};
RN   [1] {ECO:0000313|Ensembl:ENSPCOP00000005258.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
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DR   RefSeq; XP_012503025.1; XM_012647571.1.
DR   AlphaFoldDB; A0A2K6EU79; -.
DR   STRING; 379532.ENSPCOP00000005258; -.
DR   Ensembl; ENSPCOT00000015620.1; ENSPCOP00000005258.1; ENSPCOG00000013489.1.
DR   GeneID; 105813002; -.
DR   KEGG; pcoq:105813002; -.
DR   CTD; 4917; -.
DR   GeneTree; ENSGT00940000153882; -.
DR   OMA; SHCRPAR; -.
DR   OrthoDB; 2916807at2759; -.
DR   Proteomes; UP000233160; Unplaced.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-KW.
DR   GO; GO:0005794; C:Golgi apparatus; IEA:Ensembl.
DR   GO; GO:0005102; F:signaling receptor binding; IEA:Ensembl.
DR   CDD; cd00055; EGF_Lam; 3.
DR   Gene3D; 2.40.50.120; -; 1.
DR   Gene3D; 2.60.120.260; Galactose-binding domain-like; 1.
DR   Gene3D; 2.10.25.10; Laminin; 2.
DR   InterPro; IPR008211; Laminin_N.
DR   InterPro; IPR002049; LE_dom.
DR   InterPro; IPR001134; Netrin_domain.
DR   InterPro; IPR018933; Netrin_module_non-TIMP.
DR   InterPro; IPR008993; TIMP-like_OB-fold.
DR   PANTHER; PTHR10574:SF443; -; 1.
DR   PANTHER; PTHR10574; NETRIN/LAMININ-RELATED; 1.
DR   Pfam; PF00053; Laminin_EGF; 3.
DR   Pfam; PF00055; Laminin_N; 1.
DR   Pfam; PF01759; NTR; 1.
DR   SMART; SM00643; C345C; 1.
DR   SMART; SM00180; EGF_Lam; 3.
DR   SMART; SM00136; LamNT; 1.
DR   SUPFAM; SSF57196; EGF/Laminin; 3.
DR   SUPFAM; SSF50242; TIMP-like; 1.
DR   PROSITE; PS01248; EGF_LAM_1; 1.
DR   PROSITE; PS50027; EGF_LAM_2; 1.
DR   PROSITE; PS51117; LAMININ_NTER; 1.
DR   PROSITE; PS50189; NTR; 1.
PE   4: Predicted;
KW   Disulfide bond {ECO:0000256|ARBA:ARBA00023157, ECO:0000256|PROSITE-
KW   ProRule:PRU00460};
KW   Laminin EGF-like domain {ECO:0000256|ARBA:ARBA00023292,
KW   ECO:0000256|PROSITE-ProRule:PRU00460};
KW   Reference proteome {ECO:0000313|Proteomes:UP000233160};
KW   Secreted {ECO:0000256|ARBA:ARBA00022525}; Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL          1..17
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           18..580
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5014444984"
FT   DOMAIN          36..254
FT                   /note="Laminin N-terminal"
FT                   /evidence="ECO:0000259|PROSITE:PS51117"
FT   DOMAIN          374..423
FT                   /note="Laminin EGF-like"
FT                   /evidence="ECO:0000259|PROSITE:PS50027"
FT   DOMAIN          441..577
FT                   /note="NTR"
FT                   /evidence="ECO:0000259|PROSITE:PS50189"
FT   DISULFID        374..386
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00460"
FT   DISULFID        376..393
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00460"
FT   DISULFID        395..404
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00460"
FT   DISULFID        407..421
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00460"
SQ   SEQUENCE   580 AA;  61791 MW;  956B60E0B221AF3B CRC64;
     MHCWPWGLLL TASTLWAALS PGPPAATDPC HDEGGAPRSC VPGLVNAALG RQVLASSTCG
     RPATRACDAS DPRRAHPAAL LTSAGGMASP LCWRSDLLPW VPLNVTLTVP LGKAFELVFV
     SLRFCSAPPA SAALLKSQDH GRSWAPLGFF SSHCGLDYGR LPAPADGPAG PGPEALCFPA
     PQAQPDGGGL LAFSVQDGSP PGLDLDSSPV LQDWVTATDI RVVLTRPATL ADTRDSEATV
     PYSYSATELQ VGGRCKCNGH ASRCLLDTQG HLICDCRHGT EGPDCGRCKP FYCDRPWQRA
     TARESHACLA CSCNGHARRC RFNMELYRLS GRRSGGVCLN CRHNTAGRHC HYCREGFYRD
     PGRALSDRHA CRACDCHPVG AAGKTCNQTT GQCPCKDGVT GLTCNRCAPG FQQSRSPVAP
     CVKTPVPGPT EESSPVEPQD CNSHCRPARG SYRISLRKFC RKDYAVQVAV GARGEARGAW
     TRFPVAVLAV FRSGEERARR GSSALWVPAQ DAACGCPRLL PGRRYLLLGG GLGAAGRGAG
     ARGPGLSAAR GSLVLPWRDA WTRRLRRLQR RERRGRCGAA
//