ID   A0A2K6EV24_PROCO        Unreviewed;       716 AA.
AC   A0A2K6EV24;
DT   28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT   28-MAR-2018, sequence version 1.
DT   24-JAN-2024, entry version 23.
DE   SubName: Full=RAP1 GTPase activating protein 2 {ECO:0000313|Ensembl:ENSPCOP00000005580.1};
GN   Name=RAP1GAP2 {ECO:0000313|Ensembl:ENSPCOP00000005580.1};
OS   Propithecus coquereli (Coquerel's sifaka) (Propithecus verreauxi
OS   coquereli).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Strepsirrhini; Lemuriformes;
OC   Indriidae; Propithecus.
OX   NCBI_TaxID=379532 {ECO:0000313|Ensembl:ENSPCOP00000005580.1, ECO:0000313|Proteomes:UP000233160};
RN   [1] {ECO:0000313|Ensembl:ENSPCOP00000005580.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
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DR   AlphaFoldDB; A0A2K6EV24; -.
DR   Ensembl; ENSPCOT00000015981.1; ENSPCOP00000005580.1; ENSPCOG00000013732.1.
DR   GeneTree; ENSGT00940000160935; -.
DR   Proteomes; UP000233160; Unplaced.
DR   GO; GO:0005096; F:GTPase activator activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0051056; P:regulation of small GTPase mediated signal transduction; IEA:InterPro.
DR   Gene3D; 6.10.140.210; -; 1.
DR   Gene3D; 3.40.50.11210; Rap/Ran-GAP; 1.
DR   InterPro; IPR035974; Rap/Ran-GAP_sf.
DR   InterPro; IPR000331; Rap/Ran_GAP_dom.
DR   PANTHER; PTHR15711; RAP GTPASE-ACTIVATING PROTEIN; 1.
DR   PANTHER; PTHR15711:SF17; RAP1 GTPASE-ACTIVATING PROTEIN 2; 1.
DR   Pfam; PF21022; Rap-GAP_dimer; 1.
DR   Pfam; PF02145; Rap_GAP; 1.
DR   SUPFAM; SSF111347; Rap/Ran-GAP; 1.
DR   PROSITE; PS50085; RAPGAP; 1.
PE   4: Predicted;
KW   GTPase activation {ECO:0000256|ARBA:ARBA00022468, ECO:0000256|PROSITE-
KW   ProRule:PRU00165}; Reference proteome {ECO:0000313|Proteomes:UP000233160}.
FT   DOMAIN          233..449
FT                   /note="Rap-GAP"
FT                   /evidence="ECO:0000259|PROSITE:PS50085"
FT   REGION          534..716
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        560..601
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        617..635
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        644..675
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   716 AA;  78531 MW;  A94ACA1B0DD0DAA4 CRC64;
     MFGRKRSVSF GGFGWIDKTM LASLKVKKQE LANSSEVSLP DRPLSPPLTA PPTMKSAEFF
     EMLEKMQDDY IPYPSIDEVV EKGGPYPLII LPQFGGYWIE DPENVGTPTS LGSSICEEEE
     EDNLSPNTFG YKLECKGEAR AYRRHFLGKD HLNFYCTGSS LGNLILSIKC EEAEGIEYLR
     IILRSKLKTV HERIPLAGLS KLPSVPQIAK AFCDDAVGLK FNPVLYPKAS QMIVSYDEHD
     VNNTFKFGVI YQKARQTLEE ELFGNNEESP AFKEFLDLLG DTISLQDFKG FRGGLDVTHG
     QTGVESVYTT FRDREIMFHV STKLPFTEGD AQQLQRKRHI GNDIVAIIFQ EENTPFVPDM
     IASNFLHAYI VVQAETPGTE TPSYKVSVTA REDVPAFGPP LPSPPVFQKG PEFREFLLTK
     LTNAENACCK SDKFAKLEDR TRAALLDNLH DELHAHTQAM LGLGPEEDKF ENGGHGGFLE
     SFKRAIRVRS HSMETMVGSQ KKLHGGAIPG SLSGGISHNS VEVTKTTFSP PVAVATAKNQ
     SRSPIKRRSG LFPRLHTGSE GQGDSRTRSD STSSTPKTPD GGHSSQEIKS ETSSNPSSPE
     ICPNKEKPFI KLKENGRANI SRSSSSTSSF SSTAGEGEAM EEGDSGSSQP STTSPFKQEV
     FVYSPSPSSE SPSLGAVATP VIMSRSPTDT KSRNSPRSNL KFRFDKLSHA SSGAGH
//