ID   A0A2K6EWI2_PROCO        Unreviewed;       444 AA.
AC   A0A2K6EWI2;
DT   28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT   28-MAR-2018, sequence version 1.
DT   27-MAR-2024, entry version 30.
DE   SubName: Full=tRNA isopentenyltransferase 1 {ECO:0000313|Ensembl:ENSPCOP00000006092.1};
GN   Name=TRIT1 {ECO:0000313|Ensembl:ENSPCOP00000006092.1};
OS   Propithecus coquereli (Coquerel's sifaka) (Propithecus verreauxi
OS   coquereli).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Strepsirrhini; Lemuriformes;
OC   Indriidae; Propithecus.
OX   NCBI_TaxID=379532 {ECO:0000313|Ensembl:ENSPCOP00000006092.1, ECO:0000313|Proteomes:UP000233160};
RN   [1] {ECO:0000313|Ensembl:ENSPCOP00000006092.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the IPP transferase family.
CC       {ECO:0000256|ARBA:ARBA00005842, ECO:0000256|RuleBase:RU003785}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   AlphaFoldDB; A0A2K6EWI2; -.
DR   Ensembl; ENSPCOT00000016591.1; ENSPCOP00000006092.1; ENSPCOG00000014150.1.
DR   GeneTree; ENSGT00390000015214; -.
DR   Proteomes; UP000233160; Unplaced.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0016765; F:transferase activity, transferring alkyl or aryl (other than methyl) groups; IEA:UniProt.
DR   GO; GO:0008033; P:tRNA processing; IEA:InterPro.
DR   Gene3D; 1.10.20.140; -; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR   HAMAP; MF_00185; IPP_trans; 1.
DR   InterPro; IPR039657; Dimethylallyltransferase.
DR   InterPro; IPR018022; IPT.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR022755; Znf_C2H2_jaz.
DR   InterPro; IPR036236; Znf_C2H2_sf.
DR   NCBIfam; TIGR00174; miaA; 1.
DR   PANTHER; PTHR11088; TRNA DIMETHYLALLYLTRANSFERASE; 1.
DR   PANTHER; PTHR11088:SF95; TRNA DIMETHYLALLYLTRANSFERASE; 1.
DR   Pfam; PF01715; IPPT; 1.
DR   Pfam; PF12171; zf-C2H2_jaz; 1.
DR   SUPFAM; SSF57667; beta-beta-alpha zinc fingers; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|RuleBase:RU003785};
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741,
KW   ECO:0000256|RuleBase:RU003785};
KW   Reference proteome {ECO:0000313|Proteomes:UP000233160};
KW   Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000256|RuleBase:RU003785};
KW   Zinc {ECO:0000256|ARBA:ARBA00022833};
KW   Zinc-finger {ECO:0000256|ARBA:ARBA00022771}.
FT   DOMAIN          372..396
FT                   /note="Zinc finger double-stranded RNA binding"
FT                   /evidence="ECO:0000259|Pfam:PF12171"
FT   REGION          406..444
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        419..435
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   444 AA;  49605 MW;  F5A0AB86CF50BA49 CRC64;
     MAAMAAVAAA RAVSVGPGSR VLHQTLPLVV ILGATGTGKS TLALQLGQRL GGEIVSADSM
     QVYEGLDIIT NKVSAQEQRI CRHHMISFVD PLVTNYTVVD FRNKATALIE DIFARDKIPI
     VVGGTNYYIE SLLWKVLVNT KPQEMATEKA ADRKAELEKE DGHALHRRLS QVDPEMAAKL
     HPHDKRKVAR SLQVFEETGV SHSEFLHRQH AEEGGGPLGG PLKFSNPCIL WLHADQTVLD
     ERLDKRVDDM LAAGLLEELR DFHRRYNQKN ASENSQDYQH GIFQSIGFKE FHEYLITEGK
     CTPETSNQLL KKGPGPSVPP IYGLEVSDVS KWEESVLEPA LQIVQSFIQG HKPAAAPIKI
     PYNEAENKRS YHMCDFCDRI IIGDREWAAH IKSKSHLHQL KKRRRLDSDA VNTIESQSIS
     PDRDKELEEK GSPGQSDQEL KPNN
//