ID A0A2K6EWR2_PROCO Unreviewed; 1461 AA.
AC A0A2K6EWR2;
DT 28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT 28-MAR-2018, sequence version 1.
DT 24-JAN-2024, entry version 30.
DE SubName: Full=Gem nuclear organelle associated protein 5 {ECO:0000313|Ensembl:ENSPCOP00000006143.1};
GN Name=GEMIN5 {ECO:0000313|Ensembl:ENSPCOP00000006143.1};
OS Propithecus coquereli (Coquerel's sifaka) (Propithecus verreauxi
OS coquereli).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Strepsirrhini; Lemuriformes;
OC Indriidae; Propithecus.
OX NCBI_TaxID=379532 {ECO:0000313|Ensembl:ENSPCOP00000006143.1, ECO:0000313|Proteomes:UP000233160};
RN [1] {ECO:0000313|Ensembl:ENSPCOP00000006143.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
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DR STRING; 379532.ENSPCOP00000006143; -.
DR Ensembl; ENSPCOT00000016647.1; ENSPCOP00000006143.1; ENSPCOG00000014184.1.
DR GeneTree; ENSGT00620000088064; -.
DR OMA; YWFNRND; -.
DR Proteomes; UP000233160; Unplaced.
DR GO; GO:0005829; C:cytosol; IEA:Ensembl.
DR GO; GO:0016604; C:nuclear body; IEA:Ensembl.
DR GO; GO:0032797; C:SMN complex; IEA:Ensembl.
DR GO; GO:0034718; C:SMN-Gemin2 complex; IEA:Ensembl.
DR GO; GO:0003730; F:mRNA 3'-UTR binding; IEA:Ensembl.
DR GO; GO:0043022; F:ribosome binding; IEA:Ensembl.
DR GO; GO:0000340; F:RNA 7-methylguanosine cap binding; IEA:Ensembl.
DR GO; GO:0030619; F:U1 snRNA binding; IEA:Ensembl.
DR GO; GO:0030621; F:U4 snRNA binding; IEA:Ensembl.
DR GO; GO:0030622; F:U4atac snRNA binding; IEA:Ensembl.
DR GO; GO:0006417; P:regulation of translation; IEA:Ensembl.
DR GO; GO:0000387; P:spliceosomal snRNP assembly; IEA:Ensembl.
DR Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 2.
DR InterPro; IPR024977; Apc4-like_WD40_dom.
DR InterPro; IPR020472; G-protein_beta_WD-40_rep.
DR InterPro; IPR011047; Quinoprotein_ADH-like_supfam.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR InterPro; IPR019775; WD40_repeat_CS.
DR InterPro; IPR036322; WD40_repeat_dom_sf.
DR InterPro; IPR001680; WD40_rpt.
DR PANTHER; PTHR46362; GEM-ASSOCIATED PROTEIN 5; 1.
DR PANTHER; PTHR46362:SF1; GEM-ASSOCIATED PROTEIN 5; 1.
DR Pfam; PF12894; ANAPC4_WD40; 2.
DR Pfam; PF00400; WD40; 4.
DR PRINTS; PR00320; GPROTEINBRPT.
DR SMART; SM00320; WD40; 12.
DR SUPFAM; SSF50998; Quinoprotein alcohol dehydrogenase-like; 1.
DR SUPFAM; SSF50978; WD40 repeat-like; 1.
DR PROSITE; PS00678; WD_REPEATS_1; 1.
DR PROSITE; PS50082; WD_REPEATS_2; 3.
DR PROSITE; PS50294; WD_REPEATS_REGION; 2.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000233160};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW WD repeat {ECO:0000256|ARBA:ARBA00022574, ECO:0000256|PROSITE-
KW ProRule:PRU00221}.
FT REPEAT 60..104
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 241..264
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT DOMAIN 422..479
FT /note="Anaphase-promoting complex subunit 4-like WD40"
FT /evidence="ECO:0000259|Pfam:PF12894"
FT DOMAIN 494..542
FT /note="Anaphase-promoting complex subunit 4-like WD40"
FT /evidence="ECO:0000259|Pfam:PF12894"
FT REPEAT 589..622
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REGION 669..743
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1264..1294
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1346..1385
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 675..689
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 704..723
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1264..1287
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1346..1378
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1461 AA; 162773 MW; 6BCBBD65DCEA2CE9 CRC64;
MGQEPRTLPP SPNWYCARCS DAVPGGLFGF AARTSVFLVR VGPGAGASPG TPPFRVIGEL
VGHTERVSGF TFSHHPGQYN LCATSSDDGT VKIWDVETKT VVTEHALHQH TISALHWSPR
VKDLIVSGDE KGVVFCYWLN RSDSQHLFIE PRTIFCLTCS PHHEDLIAIG YKDGIVVIID
ISKKGEIIHR LRGHDDEIHS IAWCPLPGED CLSINQEENS EEPEIPNGKA TAQTPVTKGC
YVATGSKDQT IRIWSCSRGR GVMILKLPFL KRRGGGIDPT VKERLWLTLH WSSDQPTQLV
SSCFGGELLL WDLTQSWRRK YTLFSASSEG QNHSRIVFNL CPLQTEDDKQ LLLSTSMDRD
IKCWDMATLE CCWTLPSLGG FAYSLAFSPV DIGCLAIGVG DGMIRVWNTL SIKNNYDVKN
FWQGVKSKVT ALCWHPAKEG CLAFGTDDGK VGLYDTYSNK PPQISSTYHK KTVYTLAWGP
PVPPMSLYKM PVHTEISWKA DGKVMALGNE DGSIEIFQVP NLKLMCTILQ HHKLVNTISW
HHEHGSQPEL SYLMASGSNN AVIYVHNLKA VIESNPESPV TITEPYRTLS GHTAKITSLA
WSPHHDGRLV SASYDGTAQV WDAVREEPLC NFRGHRGRLL CVAWSPLDPD CIYSGADDFC
VYKWLTSMQD HSRPPQGKKS IELEKKRLSQ PKPKPKKKKK PTLRAPVKLD SMDGNEEESV
KENLGPVENG VSDQEGEEEA QEPELPCSLA AVVSREPVTC TAVSSGFEKS KVTINNKVTF
LKKEPPKEKP EALIKKRKAR SMLPLSTSLD HRSKEELHQD CLVLASAKHS KELNEDVSAD
LEERFHLGLF TDRATLYRMI EIEGKGHLEN GHPDLFHQLM LWKGDLKGVL QTAAERGELT
DNLVAMAPVA GYHVWLWAVE AFAKQLCFQD QYVKAASHLL SIHKVYEAVE LLKSNHFYRE
AIAIAKARLR PEDPILKDLY LSWGTVLERD GHYAIAAKCY LGATSAYDAA KVLAKKGDAA
SLRTAAELAA IVGEDELSAS LALRCAQELL LARNWVGAQE ALQLHESLQG QRLVFCLLEL
LSRHLEEKQF SEGKSSSSSY HSWTTGTEGP FVERVTAVWR SAFSVDTPEQ CQAAFQKLQN
IQYPSATSNT PSKQLLLHVC HDLTLAVLSQ QAARWGEAVQ ALLRAVVRSY DSGSFTVMQE
VHSAFLPEGC DHLREKLGEH QSPATPAFKS LEAFFVYGRL YEFWWSLSSP CPKSSVWVRA
GHSRTPSVEQ SQQLDSAGTT ENEASQPEAS RPPELHLTLT EESERMLSAC KDLLSEKHAS
LQNSQRTVAE VQETLAEMIR QHQKSQLCKS TVNGADKNGP EQEAEQSLSG QSQCKEEKNE
PVSLPELTKR LTEANERMAK FPEGIKAWPF PDVLECCLVL LHIASQCPSY VTQEMQQQAQ
ELLQKYGNTK AYQRHCQTFC T
//
