ID A0A2K6EX64_PROCO Unreviewed; 472 AA.
AC A0A2K6EX64;
DT 28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT 28-MAR-2018, sequence version 1.
DT 24-JAN-2024, entry version 28.
DE SubName: Full=DIX domain containing 1 {ECO:0000313|Ensembl:ENSPCOP00000006331.1};
GN Name=DIXDC1 {ECO:0000313|Ensembl:ENSPCOP00000006331.1};
OS Propithecus coquereli (Coquerel's sifaka) (Propithecus verreauxi
OS coquereli).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Strepsirrhini; Lemuriformes;
OC Indriidae; Propithecus.
OX NCBI_TaxID=379532 {ECO:0000313|Ensembl:ENSPCOP00000006331.1, ECO:0000313|Proteomes:UP000233160};
RN [1] {ECO:0000313|Ensembl:ENSPCOP00000006331.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
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DR RefSeq; XP_012514603.1; XM_012659149.1.
DR AlphaFoldDB; A0A2K6EX64; -.
DR Ensembl; ENSPCOT00000016864.1; ENSPCOP00000006331.1; ENSPCOG00000014302.1.
DR GeneID; 105822209; -.
DR CTD; 85458; -.
DR GeneTree; ENSGT00950000182903; -.
DR OMA; MPHISAR; -.
DR OrthoDB; 3042644at2759; -.
DR Proteomes; UP000233160; Unplaced.
DR GO; GO:0016055; P:Wnt signaling pathway; IEA:UniProtKB-KW.
DR Gene3D; 2.40.240.130; -; 1.
DR InterPro; IPR001158; DIX.
DR InterPro; IPR038207; DIX_dom_sf.
DR InterPro; IPR015506; Dsh/Dvl-rel.
DR InterPro; IPR029071; Ubiquitin-like_domsf.
DR PANTHER; PTHR10878:SF22; DIXIN; 1.
DR PANTHER; PTHR10878; SEGMENT POLARITY PROTEIN DISHEVELLED; 1.
DR Pfam; PF00778; DIX; 1.
DR SMART; SM00021; DAX; 1.
DR SUPFAM; SSF54236; Ubiquitin-like; 1.
DR PROSITE; PS50841; DIX; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Developmental protein {ECO:0000256|ARBA:ARBA00022473};
KW Reference proteome {ECO:0000313|Proteomes:UP000233160};
KW Wnt signaling pathway {ECO:0000256|ARBA:ARBA00022687, ECO:0000256|PROSITE-
KW ProRule:PRU00069}.
FT DOMAIN 389..469
FT /note="DIX"
FT /evidence="ECO:0000259|PROSITE:PS50841"
FT REGION 1..63
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 346..385
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 70..97
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 125..215
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 1..24
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 346..363
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 364..385
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 472 AA; 53943 MW; C0142FB80C73C50F CRC64;
MGGTQVKCLT SPSPIHSAKS ESIITQSEEK ADFVIIPSEG IENRTEETDS PLSRDWRPGS
PGTYLESSWE EQLLEQQEHL EKEMEEAKKM ISGLQALLLN GSLPEDEQER PLALCEPGVN
PEEQLIIIQS RLDQSMEENQ DLKKELLKCK QEARNLQGIK DALQQRLTQQ DTSVLQLKQE
LLRANMDKDE LHNQNVDLQR KLDERNRLLG EYKKELGQKD RLLQQHQVKL EEALRKLSDA
SYHQVDLERE LEHKDVLLAH CMKREADEVT NYNSHNSQSN GFLLPTAGKG AASVTHRGTS
DLQLVRDALR SLRNSFSGHD PQHHTIDSLE QGISSLMERL HVMEMQKKQE RKVRGKSPRT
QADSEYRDSW PPNSKLPHSQ SSPTVSSTCT KVLYFTDRSL TPFMVNIPKR LGEVTLKDFK
AAIDREGNHR YHFKALDPEF GTVKEEVFHD DDAIPGWEGK IVAWVEEDHG EN
//
