ID   A0A2K6EX76_PROCO        Unreviewed;       454 AA.
AC   A0A2K6EX76;
DT   28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT   28-MAR-2018, sequence version 1.
DT   24-JAN-2024, entry version 25.
DE   SubName: Full=DIX domain containing 1 {ECO:0000313|Ensembl:ENSPCOP00000006337.1};
GN   Name=DIXDC1 {ECO:0000313|Ensembl:ENSPCOP00000006337.1};
OS   Propithecus coquereli (Coquerel's sifaka) (Propithecus verreauxi
OS   coquereli).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Strepsirrhini; Lemuriformes;
OC   Indriidae; Propithecus.
OX   NCBI_TaxID=379532 {ECO:0000313|Ensembl:ENSPCOP00000006337.1, ECO:0000313|Proteomes:UP000233160};
RN   [1] {ECO:0000313|Ensembl:ENSPCOP00000006337.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
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DR   AlphaFoldDB; A0A2K6EX76; -.
DR   Ensembl; ENSPCOT00000016870.1; ENSPCOP00000006337.1; ENSPCOG00000014302.1.
DR   GeneTree; ENSGT00950000182903; -.
DR   Proteomes; UP000233160; Unplaced.
DR   GO; GO:0016055; P:Wnt signaling pathway; IEA:UniProtKB-KW.
DR   Gene3D; 2.40.240.130; -; 1.
DR   InterPro; IPR001158; DIX.
DR   InterPro; IPR038207; DIX_dom_sf.
DR   InterPro; IPR015506; Dsh/Dvl-rel.
DR   InterPro; IPR029071; Ubiquitin-like_domsf.
DR   PANTHER; PTHR10878:SF22; DIXIN; 1.
DR   PANTHER; PTHR10878; SEGMENT POLARITY PROTEIN DISHEVELLED; 1.
DR   Pfam; PF00778; DIX; 1.
DR   SMART; SM00021; DAX; 1.
DR   SUPFAM; SSF54236; Ubiquitin-like; 1.
DR   PROSITE; PS50841; DIX; 1.
PE   4: Predicted;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Developmental protein {ECO:0000256|ARBA:ARBA00022473};
KW   Reference proteome {ECO:0000313|Proteomes:UP000233160};
KW   Wnt signaling pathway {ECO:0000256|ARBA:ARBA00022687, ECO:0000256|PROSITE-
KW   ProRule:PRU00069}.
FT   DOMAIN          371..451
FT                   /note="DIX"
FT                   /evidence="ECO:0000259|PROSITE:PS50841"
FT   REGION          1..64
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          328..367
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          70..97
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          128..197
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COMPBIAS        1..24
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        328..345
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        346..367
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   454 AA;  51801 MW;  C77E330163A1A6CA CRC64;
     MGGTQVKCLT SPSPIHSAKS ESIITQSEEK ADFVIIPSEG IENRTEETDS PLSRDWRPGS
     PGTYLESSWE EQLLEQQEHL EKEMEEAKKM ISGLQALLLN GSLPEDEQER PLALCEPGVN
     PEEQLKELLK CKQEARNLQG IKDALQQRLT QQDTSVLQLK QELLRANMDK DELHNQNVDL
     QRKLDERNRL LGEYKKELGQ KDRLLQQHQV KLEEALRKLS DASYHQVDLE RELEHKDVLL
     AHCMKREADE VTNYNSHNSQ SNGFLLPTAG KGAASVTHRG TSDLQLVRDA LRSLRNSFSG
     HDPQHHTIDS LEQGISSLME RLHVMEMQKK QERKVRGKSP RTQADSEYRD SWPPNSKLPH
     SQSSPTVSST CTKVLYFTDR SLTPFMVNIP KRLGEVTLKD FKAAIDREGN HRYHFKALDP
     EFGTVKEEVF HDDDAIPGWE GKIVAWVEED HGEN
//