ID A0A2K6EZ96_PROCO Unreviewed; 991 AA.
AC A0A2K6EZ96;
DT 28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT 28-MAR-2018, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE SubName: Full=RNA binding motif protein 6 {ECO:0000313|Ensembl:ENSPCOP00000007065.1};
GN Name=RBM6 {ECO:0000313|Ensembl:ENSPCOP00000007065.1};
OS Propithecus coquereli (Coquerel's sifaka) (Propithecus verreauxi
OS coquereli).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Strepsirrhini; Lemuriformes;
OC Indriidae; Propithecus.
OX NCBI_TaxID=379532 {ECO:0000313|Ensembl:ENSPCOP00000007065.1, ECO:0000313|Proteomes:UP000233160};
RN [1] {ECO:0000313|Ensembl:ENSPCOP00000007065.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
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DR AlphaFoldDB; A0A2K6EZ96; -.
DR Ensembl; ENSPCOT00000017605.1; ENSPCOP00000007065.1; ENSPCOG00000014743.1.
DR GeneTree; ENSGT00940000157976; -.
DR OMA; REVGSCM; -.
DR Proteomes; UP000233160; Unplaced.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-UniRule.
DR CDD; cd12314; RRM1_RBM6; 1.
DR CDD; cd12563; RRM2_RBM6; 1.
DR Gene3D; 3.30.70.330; -; 2.
DR Gene3D; 2.160.20.80; E3 ubiquitin-protein ligase SopA; 1.
DR InterPro; IPR000467; G_patch_dom.
DR InterPro; IPR012677; Nucleotide-bd_a/b_plait_sf.
DR InterPro; IPR041591; OCRE.
DR InterPro; IPR035979; RBD_domain_sf.
DR InterPro; IPR034123; RBM6_RRM1.
DR InterPro; IPR034125; RBM6_RRM2.
DR InterPro; IPR000504; RRM_dom.
DR PANTHER; PTHR13948; RNA-BINDING PROTEIN; 1.
DR PANTHER; PTHR13948:SF22; RNA-BINDING PROTEIN 6; 1.
DR Pfam; PF01585; G-patch; 1.
DR Pfam; PF17780; OCRE; 1.
DR SMART; SM00443; G_patch; 1.
DR SMART; SM00360; RRM; 2.
DR SUPFAM; SSF141571; Pentapeptide repeat-like; 1.
DR SUPFAM; SSF54928; RNA-binding domain, RBD; 2.
DR PROSITE; PS50174; G_PATCH; 1.
DR PROSITE; PS50102; RRM; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000233160};
KW RNA-binding {ECO:0000256|ARBA:ARBA00022884, ECO:0000256|PROSITE-
KW ProRule:PRU00176}.
FT DOMAIN 324..404
FT /note="RRM"
FT /evidence="ECO:0000259|PROSITE:PS50102"
FT DOMAIN 919..965
FT /note="G-patch"
FT /evidence="ECO:0000259|PROSITE:PS50174"
FT REGION 104..258
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 282..306
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 441..516
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 609..654
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 682..815
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 872..975
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 844..871
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 111..156
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 175..215
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 219..248
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 462..516
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 610..639
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 640..654
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 692..732
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 740..754
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 872..920
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 991 AA; 114005 MW; BC2EA0EF5A1C6AD5 CRC64;
VDYRGGDGTS MDYRGRETSH MNYRDRDTHT VDFRGRDAPL SDFRGRGTYD LDFRGQDGSH
ANFRGRDLSD LDFRARDQAR SDFRNRDVSD VDFRDKDGTQ VDFRGLGSGT TDLDFRDRDT
PHSDFRGRHR SRTDQDFRGR EMGPCMEFKD REMPPVDPNI LDYIQPSTQD REQSGMNVNK
REESTHDRTI ERPAFGIQKG EFEHSETREG ETQGVAFEHE SPSDFQNNQS PIQDQDKSQL
SGGEQQSSDA GLFKEEGGLD FLGQQDTDYR SMEYRDVDHR LPGSQIFGYG QSKSFPEGET
ARDAQRDLQD QDYRTGPSEE KPSRLIQLSG VPENATKEEI LNAFRTPDGM PVKNLELKEY
NTGYDYGYVC VEFSLLEDAI GCMEANQGTL MIHEKEVTLE YVPSPDFWYC KRCKASTGGH
RSSCSFCKCP REVTETKQEL ITYPQPQKTF IPAPLEKQPN QPPRPADKEP EPRKREEGQE
PRLGHQKREA ERYQPPSRRE GLTFRRDREK EPWSGETCQD VESKTIMLKR IYRSTPPEVI
VEVLEPYVRL TTANVRIIKN RTGPMGHTYG FIDLDSHAEA LRVVKILQNL DPPFSIDGKM
VAVNLATGKR RNDSGDHSDH MHYYQGKKYF RDRRGSGRNS EWPSDTNRQG QQSSSDCYIY
DSATGYYYDP LAGTYYDPNT QQEVYVPQDP GSPEEEEIKE KKSTSQGKSS SKKDTSKRDG
KEKKDRGMTR FQENTSEGKA PPEDVFKKPL PPTVKKEESP PPPKVVNPLI GLLGEYGGDS
DYEEEEEEEQ TPPPQPRTVQ PQQREELTKK ENEEDRLTDW NKLACLLCRR QFPNKEVLIK
HQQLSDLHKQ NLEIHRKIKQ SEQELAYLER REREGKFKER GNDRREKLQS FDSPERKRIK
YSRETDSDRK PVDKEDIDTS SKGGCIQQAT GWKKGTGLGY GHPGLASSEE TEGRMRGPSI
GAPGRTSKRQ SNETYRDAVR RVMFARYKEL D
//
