ID   A0A2K6EZK0_PROCO        Unreviewed;       609 AA.
AC   A0A2K6EZK0;
DT   28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT   28-MAR-2018, sequence version 1.
DT   27-MAR-2024, entry version 31.
DE   SubName: Full=Zinc finger and SCAN domain containing 12 {ECO:0000313|Ensembl:ENSPCOP00000007144.1};
GN   Name=ZSCAN12 {ECO:0000313|Ensembl:ENSPCOP00000007144.1};
OS   Propithecus coquereli (Coquerel's sifaka) (Propithecus verreauxi
OS   coquereli).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Strepsirrhini; Lemuriformes;
OC   Indriidae; Propithecus.
OX   NCBI_TaxID=379532 {ECO:0000313|Ensembl:ENSPCOP00000007144.1, ECO:0000313|Proteomes:UP000233160};
RN   [1] {ECO:0000313|Ensembl:ENSPCOP00000007144.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|PROSITE-ProRule:PRU00187}.
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DR   AlphaFoldDB; A0A2K6EZK0; -.
DR   STRING; 379532.ENSPCOP00000007144; -.
DR   Ensembl; ENSPCOT00000017685.1; ENSPCOP00000007144.1; ENSPCOG00000014791.1.
DR   GeneTree; ENSGT00940000163105; -.
DR   OMA; CHQCKEC; -.
DR   Proteomes; UP000233160; Unplaced.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   CDD; cd07936; SCAN; 1.
DR   Gene3D; 3.30.160.60; Classic Zinc Finger; 11.
DR   Gene3D; 1.10.4020.10; DNA breaking-rejoining enzymes; 1.
DR   InterPro; IPR003309; SCAN_dom.
DR   InterPro; IPR038269; SCAN_sf.
DR   InterPro; IPR036236; Znf_C2H2_sf.
DR   InterPro; IPR013087; Znf_C2H2_type.
DR   PANTHER; PTHR24381:SF390; B-CELL CLL_LYMPHOMA 6 MEMBER B PROTEIN; 1.
DR   PANTHER; PTHR24381; ZINC FINGER PROTEIN; 1.
DR   Pfam; PF02023; SCAN; 1.
DR   Pfam; PF00096; zf-C2H2; 10.
DR   SMART; SM00431; SCAN; 1.
DR   SMART; SM00355; ZnF_C2H2; 10.
DR   SUPFAM; SSF57667; beta-beta-alpha zinc fingers; 6.
DR   SUPFAM; SSF47353; Retrovirus capsid dimerization domain-like; 1.
DR   PROSITE; PS50804; SCAN_BOX; 1.
DR   PROSITE; PS00028; ZINC_FINGER_C2H2_1; 9.
DR   PROSITE; PS50157; ZINC_FINGER_C2H2_2; 10.
PE   4: Predicted;
KW   Metal-binding {ECO:0000256|PROSITE-ProRule:PRU00042};
KW   Nucleus {ECO:0000256|PROSITE-ProRule:PRU00187};
KW   Reference proteome {ECO:0000313|Proteomes:UP000233160};
KW   Zinc {ECO:0000256|PROSITE-ProRule:PRU00042};
KW   Zinc-finger {ECO:0000256|PROSITE-ProRule:PRU00042}.
FT   DOMAIN          49..131
FT                   /note="SCAN box"
FT                   /evidence="ECO:0000259|PROSITE:PS50804"
FT   DOMAIN          279..306
FT                   /note="C2H2-type"
FT                   /evidence="ECO:0000259|PROSITE:PS50157"
FT   DOMAIN          307..334
FT                   /note="C2H2-type"
FT                   /evidence="ECO:0000259|PROSITE:PS50157"
FT   DOMAIN          335..362
FT                   /note="C2H2-type"
FT                   /evidence="ECO:0000259|PROSITE:PS50157"
FT   DOMAIN          363..390
FT                   /note="C2H2-type"
FT                   /evidence="ECO:0000259|PROSITE:PS50157"
FT   DOMAIN          391..418
FT                   /note="C2H2-type"
FT                   /evidence="ECO:0000259|PROSITE:PS50157"
FT   DOMAIN          419..446
FT                   /note="C2H2-type"
FT                   /evidence="ECO:0000259|PROSITE:PS50157"
FT   DOMAIN          447..473
FT                   /note="C2H2-type"
FT                   /evidence="ECO:0000259|PROSITE:PS50157"
FT   DOMAIN          474..501
FT                   /note="C2H2-type"
FT                   /evidence="ECO:0000259|PROSITE:PS50157"
FT   DOMAIN          502..529
FT                   /note="C2H2-type"
FT                   /evidence="ECO:0000259|PROSITE:PS50157"
FT   DOMAIN          530..557
FT                   /note="C2H2-type"
FT                   /evidence="ECO:0000259|PROSITE:PS50157"
FT   REGION          176..271
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        186..222
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        223..253
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        254..268
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   609 AA;  70551 MW;  922455663566E4C9 CRC64;
     MASTWDIQAH EDQDELLEIK IEEEEEEKYT TRQDQNLQKN NTHSREIFRR YFRQFCYQET
     SGPREALSRL RELCHQWLRP ETHTKEQILE LLVLEQFLTI LPEELQSWVQ EQHPESGEEV
     VTVLEDLERE LDEPGDQVSV HIGEQEVFLQ EMVLIGTERE HSMSLQSIKA QLKCESPELG
     VEQEQVSDVE TGNEYSNLTL KQEVSEEMEP YGNTSSRFEN DIPRSTRCGE THEPEEKTEE
     PSGYSREDKQ PTCDENGASL TENSDHTEHQ GICPGEKSYE CDDCGKAFSQ KSSLLEHQRI
     HTGDRPYKCE ECGKAFRGRT VLIRHKIVHT GEKPYKCNEC GKAFGRWSAL NQHQRLHTGE
     KHYHCNECGK AFSQKAGLFH HLKIHTRDKP YQCTQCNRSF SRRSVLTQHQ GVHTGAKPYE
     CNECGKAFVY NSSLVSHQEI HHKEKCYQCK DCGKSFSQSG LIQHQRIHTG EKPYKCDVCE
     KSFIQKASLT EHQRIHTGER PYKCNKCGKA FTQRSVLTEH QRIHTGERPY KCDECGNAFR
     GITSLIQHHR IHTGEKPYQC DDCGKAFRQR KKTSYKEILL KNQCEPQAGV NLLLSSLIPE
     WQSCCSKDL
//