ID A0A2K6FBV5_PROCO Unreviewed; 344 AA.
AC A0A2K6FBV5;
DT 28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT 28-MAR-2018, sequence version 1.
DT 24-JAN-2024, entry version 28.
DE RecName: Full=Tripartite motif-containing protein 44 {ECO:0000256|ARBA:ARBA00039455};
GN Name=TRIM44 {ECO:0000313|Ensembl:ENSPCOP00000011465.1};
OS Propithecus coquereli (Coquerel's sifaka) (Propithecus verreauxi
OS coquereli).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Strepsirrhini; Lemuriformes;
OC Indriidae; Propithecus.
OX NCBI_TaxID=379532 {ECO:0000313|Ensembl:ENSPCOP00000011465.1, ECO:0000313|Proteomes:UP000233160};
RN [1] {ECO:0000313|Ensembl:ENSPCOP00000011465.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SUBUNIT: Interacts (via coiled coil) with TRIM17 (via coiled coil).
CC {ECO:0000256|ARBA:ARBA00038610}.
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DR RefSeq; XP_012505099.1; XM_012649645.1.
DR AlphaFoldDB; A0A2K6FBV5; -.
DR STRING; 379532.ENSPCOP00000011465; -.
DR Ensembl; ENSPCOT00000022053.1; ENSPCOP00000011465.1; ENSPCOG00000017249.1.
DR GeneID; 105814604; -.
DR KEGG; pcoq:105814604; -.
DR CTD; 54765; -.
DR GeneTree; ENSGT00440000034605; -.
DR OMA; LREAYMW; -.
DR OrthoDB; 4228109at2759; -.
DR Proteomes; UP000233160; Unplaced.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR GO; GO:0061944; P:negative regulation of protein K48-linked ubiquitination; IEA:Ensembl.
DR GO; GO:0001961; P:positive regulation of cytokine-mediated signaling pathway; IEA:Ensembl.
DR GO; GO:0002230; P:positive regulation of defense response to virus by host; IEA:Ensembl.
DR GO; GO:0045893; P:positive regulation of DNA-templated transcription; IEA:Ensembl.
DR GO; GO:1901224; P:positive regulation of non-canonical NF-kappaB signal transduction; IEA:Ensembl.
DR GO; GO:0050821; P:protein stabilization; IEA:Ensembl.
DR CDD; cd19841; Bbox1_TRIM44; 1.
DR CDD; cd19784; Bbox2_TRIM44; 1.
DR Gene3D; 4.10.830.40; -; 1.
DR Gene3D; 3.30.160.60; Classic Zinc Finger; 1.
DR InterPro; IPR000315; Znf_B-box.
DR PANTHER; PTHR24103; E3 UBIQUITIN-PROTEIN LIGASE TRIM; 1.
DR PANTHER; PTHR24103:SF597; TRIPARTITE MOTIF-CONTAINING PROTEIN 44; 1.
DR Pfam; PF00643; zf-B_box; 1.
DR SMART; SM00336; BBOX; 1.
DR SUPFAM; SSF57845; B-box zinc-binding domain; 1.
DR PROSITE; PS50119; ZF_BBOX; 1.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|PROSITE-ProRule:PRU00024};
KW Reference proteome {ECO:0000313|Proteomes:UP000233160};
KW Zinc {ECO:0000256|PROSITE-ProRule:PRU00024};
KW Zinc-finger {ECO:0000256|PROSITE-ProRule:PRU00024}.
FT DOMAIN 174..215
FT /note="B box-type"
FT /evidence="ECO:0000259|PROSITE:PS50119"
FT REGION 1..25
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 78..165
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 309..344
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 92..165
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 320..334
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 344 AA; 38441 MW; 7BED2DB2EFA39ED4 CRC64;
MASGVGAAFE ELPHDGTCDE CEPDEAPGAE EVCRECGFCY CRRHAEAHRQ KFLSHHLAEY
VHGAQAWISR AGGEGAGKEE VEAKVEQERE IESEAGEESE SEEESESEEE SETEEESEDE
SDDESEEDSE EEMEDEQESE AEEDNQEEGE SEAEGETEAE SEFDPEIEME AERVAKRKCP
DHGLDLSTYC QEDRQLICVL CPVIGAHRGH QLSTLDEAFE ELRSKDSGGL KAAMIELVER
LKFKSSDPKV TRDQMKVFIQ QEFKKVQKVI ADEEQKALHL VDIQEAMATA HVTEILADIQ
SHMDRLMTQM AQAKEQLDTS NESAEPKAEG DEEGPSGASE EEDT
//
