ID   A0A2K6FDG7_PROCO        Unreviewed;      1020 AA.
AC   A0A2K6FDG7;
DT   28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT   28-MAR-2018, sequence version 1.
DT   24-JAN-2024, entry version 28.
DE   SubName: Full=Formin like 3 {ECO:0000313|Ensembl:ENSPCOP00000012014.1};
GN   Name=FMNL3 {ECO:0000313|Ensembl:ENSPCOP00000012014.1};
OS   Propithecus coquereli (Coquerel's sifaka) (Propithecus verreauxi
OS   coquereli).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Strepsirrhini; Lemuriformes;
OC   Indriidae; Propithecus.
OX   NCBI_TaxID=379532 {ECO:0000313|Ensembl:ENSPCOP00000012014.1, ECO:0000313|Proteomes:UP000233160};
RN   [1] {ECO:0000313|Ensembl:ENSPCOP00000012014.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the formin homology family.
CC       {ECO:0000256|ARBA:ARBA00023449}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   AlphaFoldDB; A0A2K6FDG7; -.
DR   Ensembl; ENSPCOT00000022606.1; ENSPCOP00000012014.1; ENSPCOG00000017512.1.
DR   GeneTree; ENSGT00940000159962; -.
DR   Proteomes; UP000233160; Unplaced.
DR   GO; GO:0003779; F:actin binding; IEA:InterPro.
DR   GO; GO:0031267; F:small GTPase binding; IEA:InterPro.
DR   GO; GO:0030036; P:actin cytoskeleton organization; IEA:InterPro.
DR   GO; GO:0022604; P:regulation of cell morphogenesis; IEA:InterPro.
DR   Gene3D; 1.20.58.2220; Formin, FH2 domain; 1.
DR   Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 2.
DR   InterPro; IPR011989; ARM-like.
DR   InterPro; IPR016024; ARM-type_fold.
DR   InterPro; IPR015425; FH2_Formin.
DR   InterPro; IPR042201; FH2_Formin_sf.
DR   InterPro; IPR010472; FH3_dom.
DR   InterPro; IPR043592; FMNL_animal.
DR   InterPro; IPR014768; GBD/FH3_dom.
DR   InterPro; IPR010473; GTPase-bd.
DR   PANTHER; PTHR45857; FORMIN-LIKE PROTEIN; 1.
DR   PANTHER; PTHR45857:SF3; FORMIN-LIKE PROTEIN 3; 1.
DR   Pfam; PF06367; Drf_FH3; 1.
DR   Pfam; PF06371; Drf_GBD; 1.
DR   Pfam; PF02181; FH2; 1.
DR   SMART; SM01139; Drf_FH3; 1.
DR   SMART; SM01140; Drf_GBD; 1.
DR   SMART; SM00498; FH2; 1.
DR   SUPFAM; SSF48371; ARM repeat; 1.
DR   SUPFAM; SSF101447; Formin homology 2 domain (FH2 domain); 1.
DR   PROSITE; PS51444; FH2; 1.
DR   PROSITE; PS51232; GBD_FH3; 1.
PE   3: Inferred from homology;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Lipoprotein {ECO:0000256|ARBA:ARBA00022707};
KW   Myristate {ECO:0000256|ARBA:ARBA00022707};
KW   Reference proteome {ECO:0000313|Proteomes:UP000233160}.
FT   DOMAIN          26..464
FT                   /note="GBD/FH3"
FT                   /evidence="ECO:0000259|PROSITE:PS51232"
FT   DOMAIN          553..943
FT                   /note="FH2"
FT                   /evidence="ECO:0000259|PROSITE:PS51444"
FT   REGION          1..22
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          483..534
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          383..456
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          917..946
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COMPBIAS        504..534
FT                   /note="Pro residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1020 AA;  116314 MW;  3E2E5DC0689B6AA9 CRC64;
     MGNLESAEGG PGEPPSVPLL LPPGKMPMPE PCELEERFAL VLSSMNLPPD KARLLRQYDN
     EKKWDLICDQ ERFQVKNPPH TYIQKLQSFL DPSVTRKKFR RRVQESTKVL RELEISLRTN
     HIGWVREFLN DENKGLDVLV DYLSFAQCSV MFDFEGLESG DDGAFDKLRS WSRSIEDLQP
     PSALSAPFTN SLARSARQSV LRYSTLPGRR ALKNSRLVSQ KDDVHVCILW LAGRSLLHHQ
     GPLLLSFPFL NNKNPRTKAL VLELLAAVCL VRGGHEIILA AFDNFKEVCK ELHRFEKLME
     YFRNEDSNID FMVACMQFIN IVVHSVEDMN FRVHLQYEFT KLGLEEFLQK SRHTESEKLQ
     VQIQAYLDNV FDVGGLLEDA ETKNVALEKV EELEEHVSHL TEKLLDLENE NMMRVAELEK
     QLLQREKELE SIKETYENTN HQVHTLRRLI KEKEEAFQRR CRLEPSARGL ESMGSEALAR
     VGPTELSEGM PPSDLDILAP DPTPEEVLPL PPPPAPPLPP PPPPLPDKCP PAPPLPGTAP
     SVVLTVGLSA IRIKKPIKTK FRLPVFNWTA LKPNQISGTV FSELDDEKIL EDLDLDKFEE
     LFKTKAQGPA LDLICSKNKT AQKAASKVTL LEANRAKNLA ITLRKAGRSA EEICRAIHTF
     DLQTLPVDFV ECLMRFLPTE AEVKLLRQYE RERQPLEELA AEDRFMLLFS KVERLTQRMA
     GMAFLGNFQD NLQMLTPQLN AIIAASASVK SSQKLKQMLE IILALGNYMN SSKRGAVYGF
     KLQSLDLLLD TKSTDRKMTL LHFIALTVKE KYPDLANFWH ELHFVEKAAA VSLENVLLDV
     KELGRGMELI RRECSIHDNS VLRSFLSTNE GKLDKLQRDA KTAEEAYNAV VRYFGESPKT
     TPPSVFFPVF VRFIRSYKEA EQENEARKKQ EEVMREKQLA QEAKKLDAKT PSQRNKWQQQ
     ELIAELRRRQ AKEHRPVYEG KDGTIEDIIT VLKSVPFTAR TAKRGSRFFC DAAHHDESNC
//