ID A0A2K6FDQ4_PROCO Unreviewed; 357 AA.
AC A0A2K6FDQ4;
DT 28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT 28-MAR-2018, sequence version 1.
DT 27-MAR-2024, entry version 28.
DE SubName: Full=Hyaluronan and proteoglycan link protein 3 {ECO:0000313|Ensembl:ENSPCOP00000012132.1};
GN Name=HAPLN3 {ECO:0000313|Ensembl:ENSPCOP00000012132.1};
OS Propithecus coquereli (Coquerel's sifaka) (Propithecus verreauxi
OS coquereli).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Strepsirrhini; Lemuriformes;
OC Indriidae; Propithecus.
OX NCBI_TaxID=379532 {ECO:0000313|Ensembl:ENSPCOP00000012132.1, ECO:0000313|Proteomes:UP000233160};
RN [1] {ECO:0000313|Ensembl:ENSPCOP00000012132.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00323}.
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DR RefSeq; XP_012499135.1; XM_012643681.1.
DR AlphaFoldDB; A0A2K6FDQ4; -.
DR STRING; 379532.ENSPCOP00000012132; -.
DR Ensembl; ENSPCOT00000022724.1; ENSPCOP00000012132.1; ENSPCOG00000017611.1.
DR GeneID; 105809824; -.
DR KEGG; pcoq:105809824; -.
DR CTD; 145864; -.
DR GeneTree; ENSGT00940000159628; -.
DR OMA; HRFDVFC; -.
DR OrthoDB; 5402504at2759; -.
DR Proteomes; UP000233160; Unplaced.
DR GO; GO:0005540; F:hyaluronic acid binding; IEA:InterPro.
DR GO; GO:0007155; P:cell adhesion; IEA:InterPro.
DR CDD; cd05877; Ig_LP_like; 1.
DR CDD; cd03518; Link_domain_HAPLN_module_1; 1.
DR CDD; cd03519; Link_domain_HAPLN_module_2; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR Gene3D; 3.10.100.10; Mannose-Binding Protein A, subunit A; 2.
DR InterPro; IPR016186; C-type_lectin-like/link_sf.
DR InterPro; IPR016187; CTDL_fold.
DR InterPro; IPR007110; Ig-like_dom.
DR InterPro; IPR036179; Ig-like_dom_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR003599; Ig_sub.
DR InterPro; IPR013106; Ig_V-set.
DR InterPro; IPR000538; Link_dom.
DR PANTHER; PTHR22804; AGGRECAN/VERSICAN PROTEOGLYCAN; 1.
DR PANTHER; PTHR22804:SF40; HYALURONAN AND PROTEOGLYCAN LINK PROTEIN 3; 1.
DR Pfam; PF07686; V-set; 1.
DR Pfam; PF00193; Xlink; 2.
DR PRINTS; PR01265; LINKMODULE.
DR SMART; SM00409; IG; 1.
DR SMART; SM00406; IGv; 1.
DR SMART; SM00445; LINK; 2.
DR SUPFAM; SSF56436; C-type lectin-like; 2.
DR SUPFAM; SSF48726; Immunoglobulin; 1.
DR PROSITE; PS50835; IG_LIKE; 1.
DR PROSITE; PS01241; LINK_1; 2.
DR PROSITE; PS50963; LINK_2; 2.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|PROSITE-ProRule:PRU00323};
KW Immunoglobulin domain {ECO:0000256|ARBA:ARBA00023319};
KW Reference proteome {ECO:0000313|Proteomes:UP000233160};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}; Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..17
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 18..357
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5014429740"
FT DOMAIN 45..161
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 163..258
FT /note="Link"
FT /evidence="ECO:0000259|PROSITE:PS50963"
FT DOMAIN 263..355
FT /note="Link"
FT /evidence="ECO:0000259|PROSITE:PS50963"
FT DISULFID 209..230
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00323"
FT DISULFID 308..329
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00323"
SQ SEQUENCE 357 AA; 40405 MW; 338F73F5F1F42E22 CRC64;
MGLLLLGLVL LLPGVSGLPF YNGFYYSNGR DPGNGHGEGL FNGVKLVVET PEETLFTYRG
ASVTLPCRYH YEPALVSPRP VRVKWWKLLE NGAPEQDVLV AIGLKLRSFG DYRGRVHLRR
DKEREVSLEI RDLRLEDYGR YRCEVIDGLE DESGLVELEL RGVVFPYQPP QGRYQLNFHE
AQQACEEQDA VVASFEQLFR AWEEGLDWCN AGWLQDASVQ YPITLPRQPC GGLGLAPGVR
SYGQRHRRLH RYDVFCFATA LKGRVYYLEH PEKLTLAEAT EACWEDGAQI AKVGQLFAAW
KFHGLDRCDA GWLADGSVRY PVAHPRPNCG PPEAGVRSFG FPDPQTSSYG VYCYRQR
//
