ID A0A2K6FJK5_PROCO Unreviewed; 421 AA.
AC A0A2K6FJK5;
DT 28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT 28-MAR-2018, sequence version 1.
DT 27-MAR-2024, entry version 31.
DE SubName: Full=Zinc finger protein 550 {ECO:0000313|Ensembl:ENSPCOP00000014155.1};
GN Name=ZNF550 {ECO:0000313|Ensembl:ENSPCOP00000014155.1};
OS Propithecus coquereli (Coquerel's sifaka) (Propithecus verreauxi
OS coquereli).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Strepsirrhini; Lemuriformes;
OC Indriidae; Propithecus.
OX NCBI_TaxID=379532 {ECO:0000313|Ensembl:ENSPCOP00000014155.1, ECO:0000313|Proteomes:UP000233160};
RN [1] {ECO:0000313|Ensembl:ENSPCOP00000014155.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
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DR RefSeq; XP_012509056.1; XM_012653602.1.
DR AlphaFoldDB; A0A2K6FJK5; -.
DR STRING; 379532.ENSPCOP00000014155; -.
DR Ensembl; ENSPCOT00000024762.1; ENSPCOP00000014155.1; ENSPCOG00000018751.1.
DR GeneID; 105817808; -.
DR KEGG; pcoq:105817808; -.
DR CTD; 162972; -.
DR GeneTree; ENSGT00940000163313; -.
DR OMA; TPYKCAE; -.
DR OrthoDB; 5250644at2759; -.
DR Proteomes; UP000233160; Unplaced.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd07765; KRAB_A-box; 1.
DR Gene3D; 6.10.140.140; -; 1.
DR Gene3D; 3.30.160.60; Classic Zinc Finger; 8.
DR InterPro; IPR001909; KRAB.
DR InterPro; IPR036051; KRAB_dom_sf.
DR InterPro; IPR036236; Znf_C2H2_sf.
DR InterPro; IPR013087; Znf_C2H2_type.
DR PANTHER; PTHR23232; KRAB DOMAIN C2H2 ZINC FINGER; 1.
DR PANTHER; PTHR23232:SF139; KRAB DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF01352; KRAB; 1.
DR Pfam; PF00096; zf-C2H2; 8.
DR SMART; SM00349; KRAB; 1.
DR SMART; SM00355; ZnF_C2H2; 8.
DR SUPFAM; SSF57667; beta-beta-alpha zinc fingers; 5.
DR SUPFAM; SSF109640; KRAB domain (Kruppel-associated box); 1.
DR PROSITE; PS50805; KRAB; 1.
DR PROSITE; PS00028; ZINC_FINGER_C2H2_1; 8.
DR PROSITE; PS50157; ZINC_FINGER_C2H2_2; 8.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000233160};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00042}.
FT DOMAIN 12..83
FT /note="KRAB"
FT /evidence="ECO:0000259|PROSITE:PS50805"
FT DOMAIN 202..229
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 230..257
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 258..285
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 286..313
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 314..341
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 342..369
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 370..397
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 398..421
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT REGION 113..160
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 119..160
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 421 AA; 48270 MW; E798060EEE227F5F CRC64;
MAAAMDAARV LVTFKDVAVT FTREEWRQLD LAQRTLYREV MLETCGLLVS LGHRVPKPEL
IHLLEHGQEL WTVKRGLAHS TCAGDRAQLQ TREPTTCLPI LFEGAFLQGS LSLGSSRDSR
LGKSRDQEGL LEMQKGQVKP RADPHKETHP EKMSLEDEGL GTEDSLHSRV LLEQVSAGDV
LLQCDSQQTG KDTSIHVRTN SYKCKQCGKG FSRKWYLVRH QRVHTGMRPY ECNACGKAFS
QSSTLIRHYL IHTGEKPYKC LDCGKAFKRR SYLMQHHPIH TGEKPYECSQ CRKAFTHRST
FIRHNRTHTG EKPFECKECD KAFSSRAHLI QHYIIHTGEK PYDCVECGKA FRCSSELMQH
QRIHTGEKPY ECTQCGKAFH RSTYLIQHSV IHTGEMPYKC IECGKAFKRR SHLLQHQRVH
T
//
