ID   A0A2K6FKS9_PROCO        Unreviewed;       479 AA.
AC   A0A2K6FKS9;
DT   28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT   28-MAR-2018, sequence version 1.
DT   27-MAR-2024, entry version 31.
DE   SubName: Full=Transcription factor CP2 like 1 {ECO:0000313|Ensembl:ENSPCOP00000014563.1};
GN   Name=TFCP2L1 {ECO:0000313|Ensembl:ENSPCOP00000014563.1};
OS   Propithecus coquereli (Coquerel's sifaka) (Propithecus verreauxi
OS   coquereli).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Strepsirrhini; Lemuriformes;
OC   Indriidae; Propithecus.
OX   NCBI_TaxID=379532 {ECO:0000313|Ensembl:ENSPCOP00000014563.1, ECO:0000313|Proteomes:UP000233160};
RN   [1] {ECO:0000313|Ensembl:ENSPCOP00000014563.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123,
CC       ECO:0000256|PROSITE-ProRule:PRU01313}.
CC   -!- SIMILARITY: Belongs to the grh/CP2 family. CP2 subfamily.
CC       {ECO:0000256|ARBA:ARBA00010852}.
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DR   RefSeq; XP_012500122.1; XM_012644668.1.
DR   AlphaFoldDB; A0A2K6FKS9; -.
DR   STRING; 379532.ENSPCOP00000014563; -.
DR   Ensembl; ENSPCOT00000025173.1; ENSPCOP00000014563.1; ENSPCOG00000018978.1.
DR   GeneID; 105810639; -.
DR   KEGG; pcoq:105810639; -.
DR   CTD; 29842; -.
DR   GeneTree; ENSGT00940000159158; -.
DR   OMA; QDESCFT; -.
DR   OrthoDB; 1363858at2759; -.
DR   Proteomes; UP000233160; Unplaced.
DR   GO; GO:0005737; C:cytoplasm; IEA:Ensembl.
DR   GO; GO:0016020; C:membrane; IEA:Ensembl.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0000978; F:RNA polymerase II cis-regulatory region sequence-specific DNA binding; IEA:Ensembl.
DR   GO; GO:0000902; P:cell morphogenesis; IEA:Ensembl.
DR   GO; GO:0007028; P:cytoplasm organization; IEA:Ensembl.
DR   GO; GO:0008340; P:determination of adult lifespan; IEA:Ensembl.
DR   GO; GO:0002070; P:epithelial cell maturation; IEA:Ensembl.
DR   GO; GO:0000122; P:negative regulation of transcription by RNA polymerase II; IEA:Ensembl.
DR   GO; GO:0045927; P:positive regulation of growth; IEA:Ensembl.
DR   GO; GO:0007431; P:salivary gland development; IEA:Ensembl.
DR   CDD; cd09590; SAM_LBP9; 1.
DR   Gene3D; 1.10.150.50; Transcription Factor, Ets-1; 1.
DR   InterPro; IPR007604; CP2.
DR   InterPro; IPR013761; SAM/pointed_sf.
DR   InterPro; IPR041418; SAM_3.
DR   InterPro; IPR040167; TF_CP2-like.
DR   InterPro; IPR037598; TFCP2L1_SAM.
DR   PANTHER; PTHR11037; TRANSCRIPTION FACTOR CP2; 1.
DR   PANTHER; PTHR11037:SF18; TRANSCRIPTION FACTOR CP2-LIKE PROTEIN 1; 1.
DR   Pfam; PF04516; CP2; 1.
DR   Pfam; PF18016; SAM_3; 1.
DR   SUPFAM; SSF47769; SAM/Pointed domain; 1.
DR   PROSITE; PS51968; GRH_CP2_DB; 1.
PE   3: Inferred from homology;
KW   DNA-binding {ECO:0000256|PROSITE-ProRule:PRU01313};
KW   Nucleus {ECO:0000256|PROSITE-ProRule:PRU01313};
KW   Reference proteome {ECO:0000313|Proteomes:UP000233160}.
FT   DOMAIN          43..280
FT                   /note="Grh/CP2 DB"
FT                   /evidence="ECO:0000259|PROSITE:PS51968"
FT   REGION          219..245
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          271..301
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        219..244
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        271..290
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   479 AA;  54622 MW;  34A7AA192F89ACC4 CRC64;
     MLFWHTQPEH YNQHSSGSYL RDVLALPIFK QEEPQLSPEN EARLPPLQYV LCAATSPAVK
     LHEETLTYLN QGQSYEIRLL ENRKLGDFQD LNTKYVKSII RVVFHDRRLQ YTEHQQLEGW
     RWSRPGDRIL DIDIPLSVGI LDPRASPTQL NAVEFLWDPA KRASAFIQVH CISTEFTPRK
     HGGEKGVPFR VQIDTFKQNE NGEYTEHLHS ASCQIKVFKP KGADRKQKTD REKMEKRTAQ
     EKEKYQPSYE TTILTECSPW PDVAYQVNSA PSPSYNGSPN SFSLGEGNNS PTHPAEALPV
     GSDHLLPSAS IQDAQQWLHR NRFSQFCRLF ASFSGADLLK MSRDDLVQIC GPADGIRLFN
     AIKGRNVRPK MTIYVCQELE QNRVALQQKR EGSGDSSLCV YHAIFLEELT TLELIEKIAN
     LYSISPQHIH RVYRQGPTGI HVVVSNEMVQ NFQDESCFVL STLKAESNDG YHIILKCGL
//