ID A0A2K6FMG4_PROCO Unreviewed; 513 AA.
AC A0A2K6FMG4;
DT 28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT 28-MAR-2018, sequence version 1.
DT 27-MAR-2024, entry version 28.
DE SubName: Full=Mex-3 RNA binding family member A {ECO:0000313|Ensembl:ENSPCOP00000015168.1};
GN Name=MEX3A {ECO:0000313|Ensembl:ENSPCOP00000015168.1};
OS Propithecus coquereli (Coquerel's sifaka) (Propithecus verreauxi
OS coquereli).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Strepsirrhini; Lemuriformes;
OC Indriidae; Propithecus.
OX NCBI_TaxID=379532 {ECO:0000313|Ensembl:ENSPCOP00000015168.1, ECO:0000313|Proteomes:UP000233160};
RN [1] {ECO:0000313|Ensembl:ENSPCOP00000015168.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR AlphaFoldDB; A0A2K6FMG4; -.
DR STRING; 379532.ENSPCOP00000015168; -.
DR Ensembl; ENSPCOT00000025781.1; ENSPCOP00000015168.1; ENSPCOG00000019307.1.
DR GeneTree; ENSGT00940000161732; -.
DR OMA; MWAGQEN; -.
DR Proteomes; UP000233160; Unplaced.
DR GO; GO:0005829; C:cytosol; IEA:Ensembl.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0000932; C:P-body; IEA:Ensembl.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-UniRule.
DR CDD; cd22423; KH-I_MEX3_rpt1; 1.
DR CDD; cd22424; KH-I_MEX3_rpt2; 1.
DR CDD; cd16518; RING-HC_MEX3; 1.
DR Gene3D; 3.30.1370.10; K Homology domain, type 1; 2.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR047228; KH-I_MEX3_rpt1.
DR InterPro; IPR047226; KH-I_MEX3_rpt2.
DR InterPro; IPR004087; KH_dom.
DR InterPro; IPR004088; KH_dom_type_1.
DR InterPro; IPR036612; KH_dom_type_1_sf.
DR InterPro; IPR047227; MEX3.
DR InterPro; IPR001841; Znf_RING.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR PANTHER; PTHR23285; RING FINGER AND KH DOMAIN CONTAINING PROTEIN 1; 1.
DR PANTHER; PTHR23285:SF2; RNA-BINDING PROTEIN MEX3A; 1.
DR Pfam; PF00013; KH_1; 2.
DR Pfam; PF13920; zf-C3HC4_3; 1.
DR SMART; SM00322; KH; 2.
DR SMART; SM00184; RING; 1.
DR SUPFAM; SSF54791; Eukaryotic type KH-domain (KH-domain type I); 2.
DR SUPFAM; SSF57850; RING/U-box; 1.
DR PROSITE; PS50084; KH_TYPE_1; 2.
DR PROSITE; PS50089; ZF_RING_2; 1.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000233160};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW RNA-binding {ECO:0000256|ARBA:ARBA00022884, ECO:0000256|PROSITE-
KW ProRule:PRU00117}; Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00175}.
FT DOMAIN 462..502
FT /note="RING-type"
FT /evidence="ECO:0000259|PROSITE:PS50089"
FT REGION 56..104
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 405..454
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 69..87
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 513 AA; 53891 MW; 4A16B0A4761024D3 CRC64;
MPSLVVSGIM ERNGGFGELG CFGGSAKDRG LLEDERALQL ALDQLCLLGL GEPPAPTEGA
GRAGAEAAPR LRPPPPPPAP PPAAQTAAPA AQTPQPPTAP KGASDAKLCA LYKEAELRLK
GSSNTTECVP VPTSEHVAEI VGRQGCKIKA LRAKTNTYIK TPVRGEEPVF MVTGRREDVA
TARREIISAA EHFSMIRASR NKSGAAFGVA PALPGQVTIR VRVPYRVVGL VVGPKGATIK
RIQQQTNTYI ITPSRDRDPV FEITGAPGNV ERAREEIETH IAVRTGKILE YNNENDFLAG
SPDAALDSRY SDAWRVHPPG CKPLSTFRQN SLGCIGECGV DSGFEAPRLG EQGGDFGYGG
YLFPGYGVGK QDVYYGVAET SPPLWAGQEN ATPTSVLFSS ASSSSSSSAK ARAGPPGAHR
SPATSAGPEL AGLPRRPPGE PLQGFSKLGG GGLRSPGGGR DCMVCFESEV TAALVPCGHN
LFCMECAVRI CERTDPECPV CHITATQAIR IFS
//
