ID A0A2K6FNS7_PROCO Unreviewed; 452 AA.
AC A0A2K6FNS7;
DT 28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT 28-MAR-2018, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE SubName: Full=Ankyrin repeat and SOCS box containing 10 {ECO:0000313|Ensembl:ENSPCOP00000015646.1};
GN Name=ASB10 {ECO:0000313|Ensembl:ENSPCOP00000015646.1};
OS Propithecus coquereli (Coquerel's sifaka) (Propithecus verreauxi
OS coquereli).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Strepsirrhini; Lemuriformes;
OC Indriidae; Propithecus.
OX NCBI_TaxID=379532 {ECO:0000313|Ensembl:ENSPCOP00000015646.1, ECO:0000313|Proteomes:UP000233160};
RN [1] {ECO:0000313|Ensembl:ENSPCOP00000015646.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- PATHWAY: Protein modification; protein ubiquitination.
CC {ECO:0000256|ARBA:ARBA00004906}.
CC -!- SIMILARITY: Belongs to the ankyrin SOCS box (ASB) family.
CC {ECO:0000256|ARBA:ARBA00005949}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR AlphaFoldDB; A0A2K6FNS7; -.
DR Ensembl; ENSPCOT00000026263.1; ENSPCOP00000015646.1; ENSPCOG00000019571.1.
DR GeneTree; ENSGT00940000158974; -.
DR UniPathway; UPA00143; -.
DR Proteomes; UP000233160; Unplaced.
DR GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
DR GO; GO:0016567; P:protein ubiquitination; IEA:UniProtKB-UniPathway.
DR Gene3D; 1.25.40.20; Ankyrin repeat-containing domain; 3.
DR InterPro; IPR002110; Ankyrin_rpt.
DR InterPro; IPR036770; Ankyrin_rpt-contain_sf.
DR InterPro; IPR001496; SOCS_box.
DR InterPro; IPR036036; SOCS_box-like_dom_sf.
DR PANTHER; PTHR24203; ANKYRIN REPEAT FAMILY PROTEIN; 1.
DR PANTHER; PTHR24203:SF45; DIEGO, ISOFORM A; 1.
DR Pfam; PF00023; Ank; 1.
DR Pfam; PF12796; Ank_2; 2.
DR Pfam; PF07525; SOCS_box; 1.
DR PRINTS; PR01415; ANKYRIN.
DR SMART; SM00248; ANK; 7.
DR SMART; SM00969; SOCS_box; 1.
DR SUPFAM; SSF48403; Ankyrin repeat; 1.
DR SUPFAM; SSF158235; SOCS box-like; 1.
DR PROSITE; PS50297; ANK_REP_REGION; 5.
DR PROSITE; PS50088; ANK_REPEAT; 5.
DR PROSITE; PS50225; SOCS; 1.
PE 3: Inferred from homology;
KW ANK repeat {ECO:0000256|ARBA:ARBA00023043, ECO:0000256|PROSITE-
KW ProRule:PRU00023}; Reference proteome {ECO:0000313|Proteomes:UP000233160}.
FT REPEAT 100..132
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 132..164
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 165..197
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 199..231
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 278..310
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT DOMAIN 405..444
FT /note="SOCS box"
FT /evidence="ECO:0000259|PROSITE:PS50225"
SQ SEQUENCE 452 AA; 49585 MW; B1B961C851407BD5 CRC64;
MPRGRKSPPR WEHHLGCLPS APTCQVWGPP SSLARGTPRP SPLLCRDMAL QNALYTGDLA
RLQELFPPNS TADLLLESQA AEPRWSSRQR GLWSLTYEEE LTTPLHVAAS RGHTEVLRLL
LRRRARPDSA PGGRTALHEA CAEGHTACVH VLLVAGADPN IPDQDGKRPL HLCRGPGALE
CAELLLRFGA RVDGRSEEEE ETPLHVAARL GHVELADLLL RRGACPDARD AEGWTPLLAA
CDTRCQSPAD AEATTARCLQ LCRLLLSAGA DADAADQDRR RPLHLACRRG HAAVVELLLS
CGVSVNAMDY GGHTALHCAL QGPAAALAQS PEHMVRALLN HDAVRVWPGA LPKVLERWCT
SPRTIEVLMN TYSGMQLPEE AMGLVPPETL QKHQRFYSSL FALARQPRSL QHLSRCALRS
HLAGCLPHAL PRLPLPPRLL RYLQLDFEDV LY
//
