ID A0A2K6FP83_PROCO Unreviewed; 678 AA.
AC A0A2K6FP83;
DT 28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT 28-MAR-2018, sequence version 1.
DT 24-JAN-2024, entry version 29.
DE SubName: Full=Vitrin {ECO:0000313|Ensembl:ENSPCOP00000015806.1};
GN Name=VIT {ECO:0000313|Ensembl:ENSPCOP00000015806.1};
OS Propithecus coquereli (Coquerel's sifaka) (Propithecus verreauxi
OS coquereli).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Strepsirrhini; Lemuriformes;
OC Indriidae; Propithecus.
OX NCBI_TaxID=379532 {ECO:0000313|Ensembl:ENSPCOP00000015806.1, ECO:0000313|Proteomes:UP000233160};
RN [1] {ECO:0000313|Ensembl:ENSPCOP00000015806.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
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DR RefSeq; XP_012509289.1; XM_012653835.1.
DR AlphaFoldDB; A0A2K6FP83; -.
DR Ensembl; ENSPCOT00000026425.1; ENSPCOP00000015806.1; ENSPCOG00000019650.1.
DR GeneID; 105817987; -.
DR CTD; 5212; -.
DR GeneTree; ENSGT00940000159330; -.
DR OrthoDB; 2883115at2759; -.
DR Proteomes; UP000233160; Unplaced.
DR CDD; cd01472; vWA_collagen; 1.
DR Gene3D; 2.170.130.20; LCCL-like domain; 1.
DR Gene3D; 3.40.50.410; von Willebrand factor, type A domain; 2.
DR InterPro; IPR004043; LCCL.
DR InterPro; IPR036609; LCCL_sf.
DR InterPro; IPR002035; VWF_A.
DR InterPro; IPR036465; vWFA_dom_sf.
DR PANTHER; PTHR24020; COLLAGEN ALPHA; 1.
DR PANTHER; PTHR24020:SF23; VITRIN; 1.
DR Pfam; PF03815; LCCL; 1.
DR Pfam; PF00092; VWA; 2.
DR PRINTS; PR00453; VWFADOMAIN.
DR SMART; SM00603; LCCL; 1.
DR SMART; SM00327; VWA; 2.
DR SUPFAM; SSF69848; LCCL domain; 1.
DR SUPFAM; SSF53300; vWA-like; 2.
DR PROSITE; PS50820; LCCL; 1.
DR PROSITE; PS50234; VWFA; 2.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000233160};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..26
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 27..678
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5014384318"
FT DOMAIN 40..133
FT /note="LCCL"
FT /evidence="ECO:0000259|PROSITE:PS50820"
FT DOMAIN 293..478
FT /note="VWFA"
FT /evidence="ECO:0000259|PROSITE:PS50234"
FT DOMAIN 495..664
FT /note="VWFA"
FT /evidence="ECO:0000259|PROSITE:PS50234"
FT REGION 143..180
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 194..256
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 143..161
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 194..218
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 228..255
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 678 AA; 73944 MW; 176A11517EDEDB39 CRC64;
MGTVVLTMKA SVIEMFLVLL VTGIHSNKEM TKKIKRLKFN VPQINCDVKA GKIINPEFIV
KCPAGCQDPK YHVYGTDVYA SYSSVCGAAV HSGVLDNSGG KILVRKVAGQ SGYKGSYSNG
VQSLSLPRWR ESFIVSESKP QKGVTYPSAL TYSSSKSPAA KAGETTKAYE RPSVPGTTAQ
PVTLMQVLAV TTAEATHTTL PKPSPSTAST TSSPRPQPMG HRSREMDLWS TPTYTSSQNR
PGANPGVQRQ DSSGAAFQKP VEADVSLGFV PKEELSTQSL EPVSLGDPNC KVDLSFLIDG
SSSIGKRRFR IQKQFLADIA QALDIGPAGP LMGVVQYGDN PATHFNLRTH TNSRDLKTAI
EKITQRGGLA NAGRAISFVT KNFFSKANGN RGGSPNVAVV LVDGWPTDKV EEASRLARES
GINIFFITIE GAVENEKQYV PEPNFVNKAV CRTNGFYSFH VQSWFGLHKT LQPLVKRVCD
TERLACSKTC LNSADVGFVI DGSSSVGTGN FRTVLQFVAN LSKEFEISDT DTRVGAVQYT
YEQRLEFGFD KYSSKADVLN AIKRVGYWSG GTSTGAAINY ALEQLFKKSK PNKRKLMILI
TDGRSYDDVR IPALAAHLKG VITYAVGVAW AAQEELEVIA THPARDHSFF VDDFDNLYQY
VSRIIRNICT EFNSQPRN
//
