ID A0A2K6G3N2_PROCO Unreviewed; 1898 AA.
AC A0A2K6G3N2;
DT 28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT 28-MAR-2018, sequence version 1.
DT 24-JAN-2024, entry version 28.
DE SubName: Full=Shroom family member 3 {ECO:0000313|Ensembl:ENSPCOP00000020849.1};
GN Name=SHROOM3 {ECO:0000313|Ensembl:ENSPCOP00000020849.1};
OS Propithecus coquereli (Coquerel's sifaka) (Propithecus verreauxi
OS coquereli).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Strepsirrhini; Lemuriformes;
OC Indriidae; Propithecus.
OX NCBI_TaxID=379532 {ECO:0000313|Ensembl:ENSPCOP00000020849.1, ECO:0000313|Proteomes:UP000233160};
RN [1] {ECO:0000313|Ensembl:ENSPCOP00000020849.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton
CC {ECO:0000256|ARBA:ARBA00004245}.
CC -!- SIMILARITY: Belongs to the shroom family.
CC {ECO:0000256|ARBA:ARBA00006469}.
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DR STRING; 379532.ENSPCOP00000020849; -.
DR Ensembl; ENSPCOT00000031506.1; ENSPCOP00000020849.1; ENSPCOG00000022412.1.
DR GeneTree; ENSGT00940000157778; -.
DR OMA; TDPLGMQ; -.
DR Proteomes; UP000233160; Unplaced.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0005874; C:microtubule; IEA:UniProtKB-KW.
DR GO; GO:0051015; F:actin filament binding; IEA:InterPro.
DR Gene3D; 6.10.250.3120; -; 1.
DR InterPro; IPR014800; ASD1_dom.
DR InterPro; IPR014799; ASD2_dom.
DR InterPro; IPR027685; Shroom_fam.
DR PANTHER; PTHR15012; APICAL PROTEIN/SHROOM-RELATED; 1.
DR PANTHER; PTHR15012:SF33; PROTEIN SHROOM3; 1.
DR Pfam; PF08688; ASD1; 1.
DR Pfam; PF08687; ASD2; 1.
DR PROSITE; PS51306; ASD1; 1.
DR PROSITE; PS51307; ASD2; 1.
PE 3: Inferred from homology;
KW Actin-binding {ECO:0000256|PROSITE-ProRule:PRU00637};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Microtubule {ECO:0000256|ARBA:ARBA00022701};
KW Reference proteome {ECO:0000313|Proteomes:UP000233160}.
FT DOMAIN 870..972
FT /note="ASD1"
FT /evidence="ECO:0000259|PROSITE:PS51306"
FT DOMAIN 1571..1859
FT /note="ASD2"
FT /evidence="ECO:0000259|PROSITE:PS51307"
FT REGION 48..114
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 212..232
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 296..330
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 345..405
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 501..583
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 622..647
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 662..1003
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1033..1567
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 347..368
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 387..401
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 503..557
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 558..582
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 672..715
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 738..758
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 924..940
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 949..973
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1116..1131
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1257..1271
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1403..1419
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1428..1446
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1498..1523
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1529..1547
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1898 AA; 203972 MW; 1924965A72BC9D7D CRC64;
LGAHCYHTIS VTLGPCVRTL GLLMHLPWAS CVKGLSGWRA ASFPVFDRDV RADPGPADTG
ASKRASPEHL GSGPQHRKAA WPGGIKPRLR HRRSDPAGRP HSWHTTKPGE NQPDASMMQI
SQGTIGPPWH QSCHSSSSTS DLSSYGHAYL RRSPDQCSSQ GSMESLEPSG AYPPCHLLSP
AKSTSSIDQL GHFHNKRDSA YSSFSTSSSI LEYPPPGISG RERSGSMDAT SARGGLLEGM
RQADIRYVKT VYDTRRGVSA EYEVNSSALL LPGRAAQASA GGQGCDKWYT VPRGKGVPPP
SWSQQCPSPL ETATDSLPPK VGAPLPPARS DSYAAFRHRE RPSSWSSLDQ KRFCRPQANS
SGSLKSPFAE EQLHTVPEGS PESSPPVKPK HNYTQKAQPG QPLLPTGIYP VPSLEPHFAQ
VPQPSVSSNG TVYPALAKES GYIAPRRACN MMATLDENGN QNGSSRPGFA FHQPVEHDLL
SPVERKPGTI AKCVPSKVHF SSVPENEEAT SLKRHLTPPQ GNSPQPSERK STHSNKPCSN
HHGLKSPQAQ AWQVGEDKRS SRLSEPCEDD FQEDHNANLP RRLHREGLGQ SLASYFGKTK
SAFSSLQNIP ESLRQQSSLE LGGGAQEGYT GGRPTCAASA KAGDPGRKAV LDHRSHLDRL
VSYPAPEGRA SASASSHGSD PRYEEPSTPP HQQTSSLGWR GLSSGSASAL QGFQNRRPHC
SVLEKVSEIE QREQGSQRPP GVGGSSYSQN SRPSRAAPTS KMPGNDLEET KANICFSKSA
EPLDSGQQHF KNGEPKLEEV SWQPCGQQRS RAADGGLGPR RPDTRLLRSQ STFQLFGEAE
EEAEWPDDRP GTPESPLQDA PFSRAYRNSI KDAQSRVLGA TSFRRRDLEL GAPAASRPWR
PRPSSAHVGL RSPEAPASAS PHTPRERHSV TPTASGPAGP ASSASRRGAR RRLTPEQKKR
SYSEPEKMNE VGVSEEAEPA PLGPQRLGPR SPEGAATDRR RVLERDGRAC AALALSGPEL
RQFQQSALAA YVHRKTGQRP ASAAGCSLQE PGLRERAQST FLQPGPAAPE GPGLASASSL
SSLREPSLQL RRDAALRPAA VSETWRAPRD RSSSFAGGRL GERRRWDPHM LGGAHGPRGA
QRVEGSPGEL SSWGAAARRA GKSVSAEDLL ERSDVLAVPV HVRSRSSPTA DKKRQDVLFG
EDNGFGLTKD PCYLAGPGSR SLSCSERGRD ETPLPHRPTP RWAGSSAPDE CPGTLDPQRQ
ASRTPSSRPP SQAAADRAAR DGQAGRQPLP PCAPAGPHGS GALAPALRPG AGDREVGSPE
RGPGAGASGR PRPPQRPPPQ AKRAPAAGED GLPAESAPES ADPTLRRKQQ RPPSSCGACD
PDTPLGAPGR ISLRISESAL RDSPPPRGDE DDDEVFAKDW RPTATPSPTS EALPPPPPPP
PGQEPPGDGW ARWDDGFPPP PAPALREVPR AGSPSKFSKV TNARERHVPA AHLEGSQILA
SRPQTSVKGS EASESSPPSV VGVQPQLAGS LGQPASVQTQ NLSYDPVGGT QGLEKKISSD
PQKSSEDIRT EALAKEIVHQ DKSLADILDP DSRMKTTMDL MEGLFPRDGN LLKENSTKRK
AMQRTVSFPG CEGKRSGDKE AVGMLVTCPA YYSVSAPKAE LLNKIKEMPA EANEEEEQAD
VNEKKAELIG SLTHKLETLQ EAKGSLLVDI KLNNALGEEV EALIRELCKP NEFDKYRMFV
GDLDKVVNLL LSLSGRLARV ENVLSSLGDD ASSEERSSLN EKRKVLAGQH EDARELKENL
DRRERVVLDI LANYLSREQL QDYQHFVKMK STLLIEQRKL DDKIRLGREQ VRCLLESLPS
DFVPKAGALA LPPDLTSETA PAAGCTLSST FPAPTSPL
//
