ID A0A2K6GD45_PROCO Unreviewed; 367 AA.
AC A0A2K6GD45;
DT 28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT 28-MAR-2018, sequence version 1.
DT 27-MAR-2024, entry version 36.
DE SubName: Full=Myocyte enhancer factor 2B {ECO:0000313|Ensembl:ENSPCOP00000024157.1};
GN Name=MEF2B {ECO:0000313|Ensembl:ENSPCOP00000024157.1};
OS Propithecus coquereli (Coquerel's sifaka) (Propithecus verreauxi
OS coquereli).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Strepsirrhini; Lemuriformes;
OC Indriidae; Propithecus.
OX NCBI_TaxID=379532 {ECO:0000313|Ensembl:ENSPCOP00000024157.1, ECO:0000313|Proteomes:UP000233160};
RN [1] {ECO:0000313|Ensembl:ENSPCOP00000024157.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
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DR RefSeq; XP_012509593.1; XM_012654139.1.
DR AlphaFoldDB; A0A2K6GD45; -.
DR STRING; 379532.ENSPCOP00000024157; -.
DR Ensembl; ENSPCOT00000034837.1; ENSPCOP00000024157.1; ENSPCOG00000024251.1.
DR GeneID; 105818198; -.
DR KEGG; pcoq:105818198; -.
DR CTD; 100271849; -.
DR GeneTree; ENSGT00940000160699; -.
DR OMA; APWQHSR; -.
DR OrthoDB; 448298at2759; -.
DR Proteomes; UP000233160; Unplaced.
DR GO; GO:0030054; C:cell junction; IEA:Ensembl.
DR GO; GO:0005829; C:cytosol; IEA:Ensembl.
DR GO; GO:0005654; C:nucleoplasm; IEA:Ensembl.
DR GO; GO:0005667; C:transcription regulator complex; IEA:Ensembl.
DR GO; GO:0001228; F:DNA-binding transcription activator activity, RNA polymerase II-specific; IEA:Ensembl.
DR GO; GO:0042826; F:histone deacetylase binding; IEA:Ensembl.
DR GO; GO:0046983; F:protein dimerization activity; IEA:InterPro.
DR GO; GO:0000978; F:RNA polymerase II cis-regulatory region sequence-specific DNA binding; IEA:Ensembl.
DR GO; GO:0048513; P:animal organ development; IEA:UniProt.
DR CDD; cd00265; MADS_MEF2_like; 1.
DR Gene3D; 3.40.1810.10; Transcription factor, MADS-box; 1.
DR InterPro; IPR033896; MADS_MEF2-like.
DR InterPro; IPR002100; TF_MADSbox.
DR InterPro; IPR036879; TF_MADSbox_sf.
DR PANTHER; PTHR48019:SF109; MYOCYTE-SPECIFIC ENHANCER FACTOR 2A; 1.
DR PANTHER; PTHR48019; SERUM RESPONSE FACTOR HOMOLOG; 1.
DR Pfam; PF00319; SRF-TF; 1.
DR PRINTS; PR00404; MADSDOMAIN.
DR SMART; SM00432; MADS; 1.
DR SUPFAM; SSF55455; SRF-like; 1.
DR PROSITE; PS00350; MADS_BOX_1; 1.
DR PROSITE; PS50066; MADS_BOX_2; 1.
PE 4: Predicted;
KW Activator {ECO:0000256|ARBA:ARBA00023159};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000233160};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 1..61
FT /note="MADS-box"
FT /evidence="ECO:0000259|PROSITE:PS50066"
FT REGION 93..125
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 148..367
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 225..239
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 247..271
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 367 AA; 38743 MW; 3B304EAF2299F78D CRC64;
MGRKKIQISR ILDQRNRQVT FTKRKFGLMK KAYELSVLCD CEIALIIFNS ANRLFQYAST
DMDRVLLKYT EYSEPHESRT NTDILETLKR RGVGLDGPEL EPDEGPEGPG EKLRRLAGEG
GDPALPRPRL YPATPAMPSP DMVYGALPPP GCDPSGLGEA LPAQSRPSPF RPAAPKAGPP
GLAHPLFSPN HLTSKTPPPL YLAADGRRPD LPGGLAGPRG GLNSRSLYGS LQSPCSAAAP
GTPLGSFPFL PAGPPEYGLG DPPPPPGLLQ SPTLAPWQSS RGDGPPAAPA PPSGGRSLGE
EGPPTRGASP PTPAVSIKSE RLSPAPGGPG DFPKTFPYPL LLARSLAEPL RPGPALRRLP
LADGWPR
//
