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Database: UniProt
Entry: A0A2K6GD49_PROCO
LinkDB: A0A2K6GD49_PROCO
Original site: A0A2K6GD49_PROCO 
ID   A0A2K6GD49_PROCO        Unreviewed;       234 AA.
AC   A0A2K6GD49;
DT   28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT   28-MAR-2018, sequence version 1.
DT   24-JAN-2024, entry version 26.
DE   SubName: Full=CKLF like MARVEL transmembrane domain containing 4 {ECO:0000313|Ensembl:ENSPCOP00000024143.1};
GN   Name=CMTM4 {ECO:0000313|Ensembl:ENSPCOP00000024143.1};
OS   Propithecus coquereli (Coquerel's sifaka) (Propithecus verreauxi
OS   coquereli).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Strepsirrhini; Lemuriformes;
OC   Indriidae; Propithecus.
OX   NCBI_TaxID=379532 {ECO:0000313|Ensembl:ENSPCOP00000024143.1, ECO:0000313|Proteomes:UP000233160};
RN   [1] {ECO:0000313|Ensembl:ENSPCOP00000024143.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR   AlphaFoldDB; A0A2K6GD49; -.
DR   STRING; 379532.ENSPCOP00000024143; -.
DR   Ensembl; ENSPCOT00000034823.1; ENSPCOP00000024143.1; ENSPCOG00000024237.1.
DR   GeneTree; ENSGT00940000159573; -.
DR   Proteomes; UP000233160; Unplaced.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR   InterPro; IPR008253; Marvel.
DR   PANTHER; PTHR22776:SF29; CKLF-LIKE MARVEL TRANSMEMBRANE DOMAIN-CONTAINING PROTEIN 4; 1.
DR   PANTHER; PTHR22776; MARVEL-CONTAINING POTENTIAL LIPID RAFT-ASSOCIATED PROTEIN; 1.
DR   Pfam; PF01284; MARVEL; 1.
DR   PROSITE; PS51225; MARVEL; 1.
PE   4: Predicted;
KW   Membrane {ECO:0000256|PROSITE-ProRule:PRU00581, ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000233160};
KW   Transmembrane {ECO:0000256|PROSITE-ProRule:PRU00581,
KW   ECO:0000256|SAM:Phobius}; Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        59..76
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        88..111
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        123..145
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        151..172
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          49..176
FT                   /note="MARVEL"
FT                   /evidence="ECO:0000259|PROSITE:PS51225"
FT   REGION          1..38
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        14..35
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   234 AA;  25943 MW;  8485BEBAFE6A93F3 CRC64;
     MRSGEELDGF EGEASSTSMI SGASSPYQPT TEPVSQRRGL AGLRCDPDYL RGTLGRLKVA
     QVVLALIAFI CIETIMECSP CEGLYFFEFV SCSALVVTGV LLVMFSLNLH MRIPQINWNL
     TDLVNTGLST FFFFIASIVL AALNHKTGAE IAAVIFGFLA TAAYAVNTFL AVQKWRVSIR
     QQSTNDYIRA RTESRDVDSR PEIQRLDTFS YSINITVRQK LPTSPLSLNH WQLA
//
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