ID A0A2K6GKY8_PROCO Unreviewed; 278 AA.
AC A0A2K6GKY8;
DT 28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT 28-MAR-2018, sequence version 1.
DT 24-JAN-2024, entry version 25.
DE SubName: Full=SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2 {ECO:0000313|Ensembl:ENSPCOP00000026877.1};
GN Name=SMARCA2 {ECO:0000313|Ensembl:ENSPCOP00000026877.1};
OS Propithecus coquereli (Coquerel's sifaka) (Propithecus verreauxi
OS coquereli).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Strepsirrhini; Lemuriformes;
OC Indriidae; Propithecus.
OX NCBI_TaxID=379532 {ECO:0000313|Ensembl:ENSPCOP00000026877.1, ECO:0000313|Proteomes:UP000233160};
RN [1] {ECO:0000313|Ensembl:ENSPCOP00000026877.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
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DR AlphaFoldDB; A0A2K6GKY8; -.
DR Ensembl; ENSPCOT00000037660.1; ENSPCOP00000026877.1; ENSPCOG00000025709.1.
DR GeneTree; ENSGT00940000154821; -.
DR Proteomes; UP000233160; Unplaced.
DR GO; GO:0016586; C:RSC-type complex; IEA:InterPro.
DR GO; GO:0006338; P:chromatin remodeling; IEA:InterPro.
DR CDD; cd05516; Bromo_SNF2L2; 1.
DR Gene3D; 1.20.920.10; Bromodomain-like; 1.
DR InterPro; IPR001487; Bromodomain.
DR InterPro; IPR036427; Bromodomain-like_sf.
DR InterPro; IPR018359; Bromodomain_CS.
DR InterPro; IPR037382; Rsc/polybromo.
DR PANTHER; PTHR16062:SF19; PROTEIN POLYBROMO-1; 1.
DR PANTHER; PTHR16062; SWI/SNF-RELATED; 1.
DR Pfam; PF00439; Bromodomain; 1.
DR PRINTS; PR00503; BROMODOMAIN.
DR SMART; SM00297; BROMO; 1.
DR SUPFAM; SSF47370; Bromodomain; 1.
DR PROSITE; PS00633; BROMODOMAIN_1; 1.
DR PROSITE; PS50014; BROMODOMAIN_2; 1.
PE 4: Predicted;
KW Bromodomain {ECO:0000256|ARBA:ARBA00023117, ECO:0000256|PROSITE-
KW ProRule:PRU00035}; Reference proteome {ECO:0000313|Proteomes:UP000233160};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..26
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 27..278
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5014364070"
FT DOMAIN 107..177
FT /note="Bromo"
FT /evidence="ECO:0000259|PROSITE:PS50014"
FT REGION 27..89
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 194..278
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 30..79
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 200..217
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 218..240
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 259..278
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 278 AA; 32016 MW; 4C87597EDE433B48 CRC64;
MLMKRLAARC FAGLLILSPL TVISDSRPAD SGKAIEDGNL EEMEEEVRLK KRKRRRNVEK
DPAKEDVEKA KKRRGRPPAE KLSPNPPKLT KQMNAIIDTV INYKDSSGRQ LSEVFIQLPS
RKELPEYYEL IRKPVDFKKI KERIRNHKYR SLGDLEKDVM LLCHNAQTFN LEGSQIYEDS
IVLQSVFKSA RQKIAKEEES EDESNEEEEE EDEEESESEA KSVKVKIKLN KKDEKGRDKG
KGKKRPNRAK AKPVVSDFDS DEEQDEHEQS EASGTDDE
//
