ID   A0A2K6GLC8_PROCO        Unreviewed;       738 AA.
AC   A0A2K6GLC8;
DT   28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT   28-MAR-2018, sequence version 1.
DT   24-JAN-2024, entry version 29.
DE   SubName: Full=Holliday junction recognition protein {ECO:0000313|Ensembl:ENSPCOP00000027033.1};
GN   Name=HJURP {ECO:0000313|Ensembl:ENSPCOP00000027033.1};
OS   Propithecus coquereli (Coquerel's sifaka) (Propithecus verreauxi
OS   coquereli).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Strepsirrhini; Lemuriformes;
OC   Indriidae; Propithecus.
OX   NCBI_TaxID=379532 {ECO:0000313|Ensembl:ENSPCOP00000027033.1, ECO:0000313|Proteomes:UP000233160};
RN   [1] {ECO:0000313|Ensembl:ENSPCOP00000027033.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
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DR   AlphaFoldDB; A0A2K6GLC8; -.
DR   STRING; 379532.ENSPCOP00000027033; -.
DR   Ensembl; ENSPCOT00000037828.1; ENSPCOP00000027033.1; ENSPCOG00000025953.1.
DR   GeneTree; ENSGT00390000005575; -.
DR   Proteomes; UP000233160; Unplaced.
DR   GO; GO:0005829; C:cytosol; IEA:Ensembl.
DR   GO; GO:0000776; C:kinetochore; IEA:Ensembl.
DR   GO; GO:0005730; C:nucleolus; IEA:Ensembl.
DR   GO; GO:0005654; C:nucleoplasm; IEA:Ensembl.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0042393; F:histone binding; IEA:Ensembl.
DR   GO; GO:0042802; F:identical protein binding; IEA:Ensembl.
DR   GO; GO:0034080; P:CENP-A containing chromatin assembly; IEA:Ensembl.
DR   GO; GO:0007059; P:chromosome segregation; IEA:Ensembl.
DR   GO; GO:0043254; P:regulation of protein-containing complex assembly; IEA:Ensembl.
DR   Gene3D; 6.10.250.2320; -; 1.
DR   InterPro; IPR022102; HJURP_C.
DR   InterPro; IPR021052; HJURP_central_dom.
DR   InterPro; IPR018465; Scm3/HJURP.
DR   PANTHER; PTHR15992; HOLLIDAY JUNCTION RECOGNITION PROTEIN; 1.
DR   PANTHER; PTHR15992:SF5; HOLLIDAY JUNCTION RECOGNITION PROTEIN; 1.
DR   Pfam; PF12347; HJURP_C; 2.
DR   Pfam; PF12346; HJURP_mid; 1.
DR   Pfam; PF10384; Scm3; 1.
PE   4: Predicted;
KW   DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW   Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW   Reference proteome {ECO:0000313|Proteomes:UP000233160}.
FT   DOMAIN          273..386
FT                   /note="Holliday junction recognition protein HJURP central"
FT                   /evidence="ECO:0000259|Pfam:PF12346"
FT   DOMAIN          410..471
FT                   /note="Holliday junction regulator protein family C-
FT                   terminal"
FT                   /evidence="ECO:0000259|Pfam:PF12347"
FT   DOMAIN          555..614
FT                   /note="Holliday junction regulator protein family C-
FT                   terminal"
FT                   /evidence="ECO:0000259|Pfam:PF12347"
FT   REGION          200..225
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          510..551
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          615..645
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          697..721
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        517..551
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        619..645
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   738 AA;  81164 MW;  B8C69E30D08030D4 CRC64;
     GLPRAMAGEV SGEDALLLQK LKDSRRRFQR RMQRLIEKYN RPFEDAPLVQ MSTLTYETPQ
     GLRIWGGGLI KERNKGQIQD SPVKPVDRIN GPVRAAVRGP ELPEQGTQVL GADAEGSEVD
     ATLDQEDPAA WAVMPAVPQS PLKNELRRKY LTQVDILLQD SGCFECVDDG HTCGKDRLVA
     LLPSLASAAM PAPGYCGGVS GKSPGDPAKP ASSPRQWDPP RPCSTDMAIV PRNDTLSLTR
     TSSSSFLSSR SFVDDDICDV TISDLYEGMV HSMSRLLSTK PSSIISTKTS IMQNWNSRRR
     HRCKSRMNKT YCKGGRHSQR LSKERFLPSS EPVQERGMLR DCKNLLDVSY RKTGLKLKKA
     VLEVKPQIHK SDLSWKELKV TPQKYSSLTY LDPNGTHSPD QENRLMTLKW LISPVKRVTG
     PRILPGHGGN HHREIEIRFD ELYREYCLTP RKQSRLTGPP NSWAVDVYKG GPTSPGGRQG
     LETHRLSFPF KKAKAKRLNE AFDAVGRRPT EVSGCLPRGG SSWSLSNTSP TPSPGPSQQM
     PDLHFQGNSS GMFRKSVWPS KAVSVPRIGP LGCGRNRYDE IKEQFDKLHQ KYCPKLPVQA
     KAPLGIGASL DKASVEVQDQ TEDLGTSNPD SRFQGSPKLS LSSSPTKSLL GSTAIVAHPS
     ACISCATGRD LQSPAKRCRL SDPWGCGHHI GSRDSSGCVG RAALGPGEQG SSSQPDSEEK
     NIFRIEEKIG FCARKIQS
//