ID   A0A2K6GMZ6_PROCO        Unreviewed;       529 AA.
AC   A0A2K6GMZ6;
DT   28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT   28-MAR-2018, sequence version 1.
DT   27-MAR-2024, entry version 26.
DE   SubName: Full=PHD finger protein 12 {ECO:0000313|Ensembl:ENSPCOP00000027577.1};
GN   Name=PHF12 {ECO:0000313|Ensembl:ENSPCOP00000027577.1};
OS   Propithecus coquereli (Coquerel's sifaka) (Propithecus verreauxi
OS   coquereli).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Strepsirrhini; Lemuriformes;
OC   Indriidae; Propithecus.
OX   NCBI_TaxID=379532 {ECO:0000313|Ensembl:ENSPCOP00000027577.1, ECO:0000313|Proteomes:UP000233160};
RN   [1] {ECO:0000313|Ensembl:ENSPCOP00000027577.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
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DR   AlphaFoldDB; A0A2K6GMZ6; -.
DR   Ensembl; ENSPCOT00000038410.1; ENSPCOP00000027577.1; ENSPCOG00000026304.1.
DR   GeneTree; ENSGT00940000155713; -.
DR   Proteomes; UP000233160; Unplaced.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   CDD; cd15534; PHD2_PHF12_Rco1; 1.
DR   Gene3D; 6.10.20.60; PHD finger protein 12; 1.
DR   Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR   InterPro; IPR031966; PHF12_MRG-bd.
DR   InterPro; IPR038098; PHF12_MRG-bd_sf.
DR   InterPro; IPR011011; Znf_FYVE_PHD.
DR   InterPro; IPR001965; Znf_PHD.
DR   InterPro; IPR019787; Znf_PHD-finger.
DR   InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR   PANTHER; PTHR46309; PHD FINGER PROTEIN 12; 1.
DR   PANTHER; PTHR46309:SF1; PHD FINGER PROTEIN 12; 1.
DR   Pfam; PF00628; PHD; 1.
DR   Pfam; PF16737; PHF12_MRG_bd; 1.
DR   SMART; SM00249; PHD; 1.
DR   SUPFAM; SSF57903; FYVE/PHD zinc finger; 1.
DR   PROSITE; PS50016; ZF_PHD_2; 1.
PE   4: Predicted;
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW   Reference proteome {ECO:0000313|Proteomes:UP000233160};
KW   Zinc {ECO:0000256|ARBA:ARBA00022833};
KW   Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW   ProRule:PRU00146}.
FT   DOMAIN          54..104
FT                   /note="PHD-type"
FT                   /evidence="ECO:0000259|PROSITE:PS50016"
FT   REGION          17..40
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          314..353
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        23..40
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        331..353
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   529 AA;  57212 MW;  A6D08AC4247BD0DC CRC64;
     MERNPTQFQL PNELTCTTAL PGSSKRRRKE ETTGKNVKKT QHELDHNGLV PLPVKVCFTC
     NRSCRVAPLI QCDYCPLLFH MDCLEPPLTA MPLGRWMCPN HIEHVVLNQK NMTLSNRCQV
     FDRFQDTISQ HVIKVDFLNR IHKKHPPNRR VLQSVKRRSL KVPDAIKSQY QFPPPLIAPA
     AIRDGELICN GIPEESQTHL LNSEHLATQA EQQEWLCSVV ALQCSILKHL SAKQMPSHWD
     SEQTEKADIK PVIVTDSSIT TSLQTADKAP TPSHYPLSCP SGISTQNSLS CSPPHQPPAL
     EDISCSSCAE KSKKAPCGTA NGPVNTEVKV NGPHLYSSPT DSTDPRRLPG TNTPLPGLSH
     RQGWPQPLTP PAAGGLQNHT VGIIVKTENA TGPSSCPQRS LVPVPSLPPS IPSSCASIEN
     TSTLQRKTIQ SQIGPPLTDS RPLGSPPNAT RVLTPPHAAG DSILATGANQ RFCSPAPSSD
     GKVSPGTLSI GSALTVPSFP ANSTAMVDLT NSLRAFMDVN GGRSPGLRE
//