ID   A0A2K6GNN5_PROCO        Unreviewed;       478 AA.
AC   A0A2K6GNN5;
DT   28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT   28-MAR-2018, sequence version 1.
DT   27-MAR-2024, entry version 35.
DE   SubName: Full=Scavenger receptor class B member 2 {ECO:0000313|Ensembl:ENSPCOP00000027853.1};
GN   Name=SCARB2 {ECO:0000313|Ensembl:ENSPCOP00000027853.1};
OS   Propithecus coquereli (Coquerel's sifaka) (Propithecus verreauxi
OS   coquereli).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Strepsirrhini; Lemuriformes;
OC   Indriidae; Propithecus.
OX   NCBI_TaxID=379532 {ECO:0000313|Ensembl:ENSPCOP00000027853.1, ECO:0000313|Proteomes:UP000233160};
RN   [1] {ECO:0000313|Ensembl:ENSPCOP00000027853.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the CD36 family.
CC       {ECO:0000256|ARBA:ARBA00010532}.
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DR   RefSeq; XP_012506444.1; XM_012650990.1.
DR   AlphaFoldDB; A0A2K6GNN5; -.
DR   STRING; 379532.ENSPCOP00000027853; -.
DR   Ensembl; ENSPCOT00000038710.1; ENSPCOP00000027853.1; ENSPCOG00000026487.1.
DR   GeneID; 105815747; -.
DR   KEGG; pcoq:105815747; -.
DR   CTD; 950; -.
DR   GeneTree; ENSGT00940000153372; -.
DR   OMA; DVFGMRP; -.
DR   OrthoDB; 315994at2759; -.
DR   Proteomes; UP000233160; Unplaced.
DR   GO; GO:0030666; C:endocytic vesicle membrane; IEA:Ensembl.
DR   GO; GO:0043202; C:lysosomal lumen; IEA:Ensembl.
DR   GO; GO:0005765; C:lysosomal membrane; IEA:Ensembl.
DR   GO; GO:0005886; C:plasma membrane; IEA:Ensembl.
DR   GO; GO:0015485; F:cholesterol binding; IEA:Ensembl.
DR   GO; GO:0019899; F:enzyme binding; IEA:Ensembl.
DR   GO; GO:0031210; F:phosphatidylcholine binding; IEA:Ensembl.
DR   GO; GO:0001786; F:phosphatidylserine binding; IEA:Ensembl.
DR   GO; GO:0042803; F:protein homodimerization activity; IEA:Ensembl.
DR   GO; GO:0051087; F:protein-folding chaperone binding; IEA:Ensembl.
DR   GO; GO:0005044; F:scavenger receptor activity; IEA:Ensembl.
DR   GO; GO:0015917; P:aminophospholipid transport; IEA:Ensembl.
DR   GO; GO:0099638; P:endosome to plasma membrane protein transport; IEA:Ensembl.
DR   GO; GO:0006622; P:protein targeting to lysosome; IEA:Ensembl.
DR   GO; GO:0006898; P:receptor-mediated endocytosis; IEA:Ensembl.
DR   GO; GO:0043470; P:regulation of carbohydrate catabolic process; IEA:Ensembl.
DR   GO; GO:0007605; P:sensory perception of sound; IEA:Ensembl.
DR   InterPro; IPR002159; CD36_fam.
DR   InterPro; IPR005429; LimpII.
DR   PANTHER; PTHR11923:SF92; LYSOSOME MEMBRANE PROTEIN 2; 1.
DR   PANTHER; PTHR11923; SCAVENGER RECEPTOR CLASS B TYPE-1 SR-B1; 1.
DR   Pfam; PF01130; CD36; 1.
DR   PRINTS; PR01609; CD36FAMILY.
DR   PRINTS; PR01611; LIMPII.
PE   3: Inferred from homology;
KW   Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Receptor {ECO:0000256|ARBA:ARBA00023170};
KW   Reference proteome {ECO:0000313|Proteomes:UP000233160};
KW   Signal {ECO:0000256|SAM:SignalP};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}.
FT   SIGNAL          1..26
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           27..478
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5014351414"
FT   TRANSMEM        438..458
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
SQ   SEQUENCE   478 AA;  54079 MW;  2CD2792B5D2AD0AE CRC64;
     MGRCCFYAAG TLSLLLLVTS VTLLVARVFQ KAVDQTIEKN IVLRNGTEIF DSWEKPPVPV
     YTQFYFFNVT NPEEILRGET PRLEEVGPYT YRELRNKANI QFGDNGTTIS AVSNKAYVFE
     RNQSVGDPKI DLIRTLNIPV LTAMEWSQVH FLREIIEAIL KTYEQKLFVT HTVDELLWGY
     KDVVLSLIHP FRPEISPYFG LFYGKNGTND GDYVFLTGED NYLDFTKIVE WNGKTSLDWW
     TTGKCNMING TDGDSFHPLI TKDEVLYVFP SDFCRSVYIT FSDFESVHGL PAFRYKVPAE
     ILANTSDNAG FCIPEGNCLG SGVLNVSICK NGAPIIMSFP HFYQADERFV SAIEGMHPNK
     EDHETFVDIN PLTGMILKAA KRFQINIYVK KLDDFVETGD IRTMVFPVMY LNESVLIDKE
     TASRLKSVIN TTLIITNIPY IIMALGVLFG LVFTWLACKG QGSMDEGTAD ERAPLIRT
//