ID A0A2K6GR00_PROCO Unreviewed; 303 AA.
AC A0A2K6GR00;
DT 28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT 28-MAR-2018, sequence version 1.
DT 24-JAN-2024, entry version 26.
DE SubName: Full=SEC22 homolog C, vesicle trafficking protein {ECO:0000313|Ensembl:ENSPCOP00000028655.1};
GN Name=SEC22C {ECO:0000313|Ensembl:ENSPCOP00000028655.1};
OS Propithecus coquereli (Coquerel's sifaka) (Propithecus verreauxi
OS coquereli).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Strepsirrhini; Lemuriformes;
OC Indriidae; Propithecus.
OX NCBI_TaxID=379532 {ECO:0000313|Ensembl:ENSPCOP00000028655.1, ECO:0000313|Proteomes:UP000233160};
RN [1] {ECO:0000313|Ensembl:ENSPCOP00000028655.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- FUNCTION: May be involved in vesicle transport between the ER and the
CC Golgi complex. {ECO:0000256|ARBA:ARBA00003595}.
CC -!- SUBCELLULAR LOCATION: Endoplasmic reticulum membrane
CC {ECO:0000256|ARBA:ARBA00004477}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004477}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the synaptobrevin family.
CC {ECO:0000256|ARBA:ARBA00008025}.
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DR RefSeq; XP_012520972.1; XM_012665518.1.
DR AlphaFoldDB; A0A2K6GR00; -.
DR STRING; 379532.ENSPCOP00000028655; -.
DR Ensembl; ENSPCOT00000039587.1; ENSPCOP00000028655.1; ENSPCOG00000026993.1.
DR GeneID; 105827386; -.
DR KEGG; pcoq:105827386; -.
DR CTD; 9117; -.
DR GeneTree; ENSGT00940000159338; -.
DR OrthoDB; 129635at2759; -.
DR Proteomes; UP000233160; Unplaced.
DR GO; GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0006888; P:endoplasmic reticulum to Golgi vesicle-mediated transport; IEA:InterPro.
DR CDD; cd14824; Longin; 1.
DR Gene3D; 3.30.450.50; Longin domain; 1.
DR InterPro; IPR011012; Longin-like_dom_sf.
DR InterPro; IPR010908; Longin_dom.
DR InterPro; IPR043546; Sec22a/c.
DR PANTHER; PTHR46258; LONGIN DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR46258:SF2; VESICLE-TRAFFICKING PROTEIN SEC22C; 1.
DR Pfam; PF13774; Longin; 1.
DR SMART; SM01270; Longin; 1.
DR SUPFAM; SSF64356; SNARE-like; 1.
DR PROSITE; PS50859; LONGIN; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000233160};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 184..204
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 224..242
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 249..266
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 272..290
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 8..119
FT /note="Longin"
FT /evidence="ECO:0000259|PROSITE:PS50859"
SQ SEQUENCE 303 AA; 34371 MW; 4966D7CA8830D709 CRC64;
MSMIFFACVV RVRDGLPLSA STDFYHTQDF LECRRQLKTL GLRLAQYPGR GSAEGRDFSI
HFSSSGDVAC MAICSHQCPA AMAFCFLETL WWEFTASYDT TCIGLASRPY AFLEFDSIIQ
KIKWHFNYVS SSQMKSSLEK IQEELEFQPP VVLTVEDTDV ANGMMNGHLP MHLERAPNFR
MEPVTALGIL SLILNIMCAA LNLIRGVHLA EHSLQVAQEE IGNILAFLIP FVACIFQCYL
YLFYSPARTM KVVLMLLFIC LGNMYLHGLR NLWQILFHIG VAFLSSYQIL TRQLQEKQSD
CGV
//
