ID   A0A2K6GRH6_PROCO        Unreviewed;      1360 AA.
AC   A0A2K6GRH6;
DT   28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT   28-MAR-2018, sequence version 1.
DT   27-MAR-2024, entry version 25.
DE   RecName: Full=Bromodomain adjacent to zinc finger domain protein 1A {ECO:0008006|Google:ProtNLM};
OS   Propithecus coquereli (Coquerel's sifaka) (Propithecus verreauxi
OS   coquereli).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Strepsirrhini; Lemuriformes;
OC   Indriidae; Propithecus.
OX   NCBI_TaxID=379532 {ECO:0000313|Ensembl:ENSPCOP00000028861.1, ECO:0000313|Proteomes:UP000233160};
RN   [1] {ECO:0000313|Ensembl:ENSPCOP00000028861.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|PROSITE-ProRule:PRU00475}.
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DR   Ensembl; ENSPCOT00000039796.1; ENSPCOP00000028861.1; ENSPCOG00000027094.1.
DR   GeneTree; ENSGT00940000166431; -.
DR   Proteomes; UP000233160; Unplaced.
DR   GO; GO:0000785; C:chromatin; IEA:UniProt.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0006338; P:chromatin remodeling; IEA:InterPro.
DR   Gene3D; 1.20.920.10; Bromodomain-like; 1.
DR   InterPro; IPR047171; BAZ1A.
DR   InterPro; IPR036427; Bromodomain-like_sf.
DR   InterPro; IPR018501; DDT_dom.
DR   InterPro; IPR028942; WHIM1_dom.
DR   InterPro; IPR028941; WHIM2_dom.
DR   InterPro; IPR013136; WSTF_Acf1_Cbp146.
DR   PANTHER; PTHR46510; BROMODOMAIN ADJACENT TO ZINC FINGER DOMAIN PROTEIN 1A; 1.
DR   PANTHER; PTHR46510:SF1; BROMODOMAIN ADJACENT TO ZINC FINGER DOMAIN PROTEIN 1A; 1.
DR   Pfam; PF02791; DDT; 1.
DR   Pfam; PF10537; WAC_Acf1_DNA_bd; 1.
DR   Pfam; PF15612; WHIM1; 1.
DR   Pfam; PF15613; WSD; 1.
DR   SMART; SM00571; DDT; 1.
DR   SUPFAM; SSF47370; Bromodomain; 1.
DR   PROSITE; PS50827; DDT; 1.
DR   PROSITE; PS51136; WAC; 1.
PE   4: Predicted;
KW   Coiled coil {ECO:0000256|SAM:Coils}; Membrane {ECO:0000256|SAM:Phobius};
KW   Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|PROSITE-
KW   ProRule:PRU00475}; Reference proteome {ECO:0000313|Proteomes:UP000233160};
KW   Transcription {ECO:0000256|ARBA:ARBA00023163};
KW   Transcription regulation {ECO:0000256|ARBA:ARBA00023015};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        1049..1065
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        1102..1120
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          22..128
FT                   /note="WAC"
FT                   /evidence="ECO:0000259|PROSITE:PS51136"
FT   DOMAIN          423..488
FT                   /note="DDT"
FT                   /evidence="ECO:0000259|PROSITE:PS50827"
FT   REGION          660..716
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          811..840
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          910..929
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          1143..1200
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          1221..1240
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          318..395
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COMPBIAS        660..688
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        811..838
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        912..929
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1360 AA;  156401 MW;  29E57BF00432FFFC CRC64;
     MPLLHRKPFV RQKPPADLRP DEEVFYCKVT NEIFRHYDDF FERTILCNSL VWSCAVTGRP
     GLTYQEALES EKKARQNLQS FPEPLIIPVL YLTNLTHRSR LHEICDDIFA YVKDRYFVEE
     TVEVIRNNGA RLQCRILEVL PPSHQNGFAN GHVSSVDGET IIISDSDDSE TQSCSVQNGK
     KKDAIDPLLF KYKVQPTKKK ELYESAIVKA TQISRRKHLF SRDKLKLFLK QHCEPQDGVI
     KIKASSLLMY KIAEQDFSYF FPDEPPTFIF SPANRRRGRP PKRISISQEH SVSNKQTIAG
     YRNKGIKERD KLLKQEEMKS LAFEKAKLKR EKADALEAKK KEKEDKEKKR EELKKIIEEE
     RLKKKEEKER LKVEREKERE KLREEKRKYM EYLKQWSKPR EDMECDDLKE LPEPTPVKTR
     LPPEIFGDAL MVLEFLNAFG ELFDLQDEFP EGVTLEVLEE ALVGNDSEGP LCELLFFFLT
     AIFQAIAEEE EEVAKEQITD ADTKDLTEAL DEDADPTKSA LSAVASLAAA WPQLHQGCSL
     KSLDLDSCTL SEILRLHILA SGADVTSANA KYRYQKRGGF DATDDACMEL RLSNPGLVKK
     LSSTSVYDLT PGEKMKILHA LCGKLLTLVS TRDYIEDYVD ILRQAKQEFR ELKAEQHRKE
     REEAAAREEE REDFDTSTES KEIEQKELDQ DMVTEDEDDS GSHKRSRRGK RGQNGFKEFT
     RQEEINCVTS EPLTVAEEEA LKQEYQRKER ELLEKIQSAI ACTNIFPLGR DRMYRRYWIF
     PSIPGLFIEE DYSGLTEDML LPKHSLFQNN VQSQDPQVST KTGESLKSES TSNIDHGPCD
     HSVQLPKPVH KPNRWCFYSS CEQLDQLIEA LNSRGYRESA LKETLLQEKS RICAQLACFS
     EEKFHFSDKP QTDSKPIYSR GRSSNAYDQS QMSAERQLEL RLRDFLLDIE DRIYQGTLGA
     IKVYMRLAAV EQGKQGPSQK VIPSAKEVHR RAACLTACLG IKTETPSTVS TNASTPQSVS
     NVVHYLAMAL FQIEQGIERR FLKAPLGKYV FYFKILVMFL TFSALDRSTI WRKDKEKWNQ
     FLNYTENLFR THWLNRTRRI ELIIRSLLFC TIIMFSNNIY SASKRGRPQV RFPIKARGRL
     SSSFSSRGQR QDSGRYPSRS QQSTPKSPVS SKTIGRSLRK INSAPPTETK SLRIASRSTR
     HSHGPLQADV FVELLSPCRK RRSRRSANNT PENSPNFPNF RVIATKSSEQ SRSLSVVSKL
     SLHDSESKRR CRKRXXXXXX XXXXXXXXXX XXVAVTEFID DIELMFSNCF EYNPRNTSEA
     KAGTRLQAFF HIQAQKLGLH VTPSNVDQVS TPPAVKKSRI
//