ID   A0A2K6GS30_PROCO        Unreviewed;       515 AA.
AC   A0A2K6GS30;
DT   28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT   28-MAR-2018, sequence version 1.
DT   24-JAN-2024, entry version 29.
DE   SubName: Full=Keratin 78 {ECO:0000313|Ensembl:ENSPCOP00000029043.1};
GN   Name=KRT78 {ECO:0000313|Ensembl:ENSPCOP00000029043.1};
OS   Propithecus coquereli (Coquerel's sifaka) (Propithecus verreauxi
OS   coquereli).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Strepsirrhini; Lemuriformes;
OC   Indriidae; Propithecus.
OX   NCBI_TaxID=379532 {ECO:0000313|Ensembl:ENSPCOP00000029043.1, ECO:0000313|Proteomes:UP000233160};
RN   [1] {ECO:0000313|Ensembl:ENSPCOP00000029043.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the intermediate filament family.
CC       {ECO:0000256|RuleBase:RU000685}.
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DR   AlphaFoldDB; A0A2K6GS30; -.
DR   STRING; 379532.ENSPCOP00000029043; -.
DR   Ensembl; ENSPCOT00000039978.1; ENSPCOP00000029043.1; ENSPCOG00000027204.1.
DR   GeneTree; ENSGT00940000162461; -.
DR   OMA; RGRNSHT; -.
DR   Proteomes; UP000233160; Unplaced.
DR   GO; GO:0045095; C:keratin filament; IEA:InterPro.
DR   Gene3D; 1.20.5.170; -; 1.
DR   Gene3D; 1.20.5.500; Single helix bin; 1.
DR   Gene3D; 1.20.5.1160; Vasodilator-stimulated phosphoprotein; 1.
DR   InterPro; IPR018039; IF_conserved.
DR   InterPro; IPR039008; IF_rod_dom.
DR   InterPro; IPR032444; Keratin_2_head.
DR   InterPro; IPR003054; Keratin_II.
DR   PANTHER; PTHR45616; GATA-TYPE DOMAIN-CONTAINING PROTEIN; 1.
DR   PANTHER; PTHR45616:SF18; KERATIN, TYPE II CYTOSKELETAL 78; 1.
DR   Pfam; PF00038; Filament; 1.
DR   Pfam; PF16208; Keratin_2_head; 1.
DR   PRINTS; PR01276; TYPE2KERATIN.
DR   SMART; SM01391; Filament; 1.
DR   SUPFAM; SSF64593; Intermediate filament protein, coiled coil region; 2.
DR   PROSITE; PS00226; IF_ROD_1; 1.
DR   PROSITE; PS51842; IF_ROD_2; 1.
PE   3: Inferred from homology;
KW   Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW   Intermediate filament {ECO:0000256|ARBA:ARBA00022754,
KW   ECO:0000256|RuleBase:RU000685}; Keratin {ECO:0000256|ARBA:ARBA00022744};
KW   Reference proteome {ECO:0000313|Proteomes:UP000233160}.
FT   DOMAIN          106..419
FT                   /note="IF rod"
FT                   /evidence="ECO:0000259|PROSITE:PS51842"
FT   REGION          1..58
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          154..209
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          317..397
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COMPBIAS        23..44
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   515 AA;  56182 MW;  3C0AF99DF27B6F75 CRC64;
     MSLSPCRAQR GFSARSACSV RSGGRRSRGS FSSRSLSSSR GCPGGSRGRT WGSGGRLGVR
     FGEGSGRPGF SLCPPGGIQE VTIDPNLLTP LKIEIDPQFQ VVRTKETREI RTLNNQFASF
     IDKVRFLEQQ NKVLETKWHL LQQQGVSGSP QDLQPAFEAY LAQLRKQLEQ LQRERGALDA
     ELKACRDQEE EYKAKYEEEA RKHATAENDF VVLKKDADGV FLSKMELDGK LAALREHICF
     LKRLYEEELG QLQTQVSDTS VVLSMDNDRC LDFSDIIAEV RAQYEQITQT SKAEAEALYQ
     TKYQELQVSA QLHGDSMKET KVRISQLHQE IQRLQSQIEN LKKQNADLQA AIAGAEQRGE
     AALKDAQAKL DELEAALRAA KQDLARLLLD YQELMSTKLS LDVEIATYRR LLEGEECRMS
     GEYTSQVTVS VVGGSTVVSG GVGGSLGGSG GLGGGKGSFG SYCSSIVTGG SSATLGSEEG
     PVWGSCSVSG SRSGSSSRTI LKKTVESSLK TSITY
//