ID A0A2K6GWE1_PROCO Unreviewed; 594 AA.
AC A0A2K6GWE1;
DT 28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT 28-MAR-2018, sequence version 1.
DT 24-JAN-2024, entry version 31.
DE SubName: Full=Multiple EGF like domains 9 {ECO:0000313|Ensembl:ENSPCOP00000030494.1};
GN Name=MEGF9 {ECO:0000313|Ensembl:ENSPCOP00000030494.1};
OS Propithecus coquereli (Coquerel's sifaka) (Propithecus verreauxi
OS coquereli).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Strepsirrhini; Lemuriformes;
OC Indriidae; Propithecus.
OX NCBI_TaxID=379532 {ECO:0000313|Ensembl:ENSPCOP00000030494.1, ECO:0000313|Proteomes:UP000233160};
RN [1] {ECO:0000313|Ensembl:ENSPCOP00000030494.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00460}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR RefSeq; XP_012519901.1; XM_012664447.1.
DR AlphaFoldDB; A0A2K6GWE1; -.
DR STRING; 379532.ENSPCOP00000030494; -.
DR Ensembl; ENSPCOT00000041442.1; ENSPCOP00000030494.1; ENSPCOG00000027969.1.
DR GeneID; 105826459; -.
DR KEGG; pcoq:105826459; -.
DR CTD; 1955; -.
DR GeneTree; ENSGT00940000161177; -.
DR OMA; YIGPNCN; -.
DR OrthoDB; 5491831at2759; -.
DR Proteomes; UP000233160; Unplaced.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR CDD; cd00055; EGF_Lam; 5.
DR Gene3D; 2.10.25.10; Laminin; 5.
DR InterPro; IPR000742; EGF-like_dom.
DR InterPro; IPR002049; LE_dom.
DR PANTHER; PTHR10574:SF298; MULTIPLE EPIDERMAL GROWTH FACTOR-LIKE DOMAINS PROTEIN 9; 1.
DR PANTHER; PTHR10574; NETRIN/LAMININ-RELATED; 1.
DR Pfam; PF00053; Laminin_EGF; 5.
DR PRINTS; PR00011; EGFLAMININ.
DR SMART; SM00181; EGF; 4.
DR SMART; SM00180; EGF_Lam; 5.
DR SUPFAM; SSF57196; EGF/Laminin; 4.
DR PROSITE; PS00022; EGF_1; 1.
DR PROSITE; PS01248; EGF_LAM_1; 3.
DR PROSITE; PS50027; EGF_LAM_2; 5.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157, ECO:0000256|PROSITE-
KW ProRule:PRU00460};
KW Laminin EGF-like domain {ECO:0000256|ARBA:ARBA00023292,
KW ECO:0000256|PROSITE-ProRule:PRU00460}; Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000233160};
KW Signal {ECO:0000256|SAM:SignalP}; Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..31
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 32..594
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5014331250"
FT TRANSMEM 507..530
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 198..247
FT /note="Laminin EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50027"
FT DOMAIN 248..294
FT /note="Laminin EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50027"
FT DOMAIN 295..342
FT /note="Laminin EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50027"
FT DOMAIN 343..393
FT /note="Laminin EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50027"
FT DOMAIN 394..445
FT /note="Laminin EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50027"
FT REGION 34..192
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 85..131
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 141..155
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 156..170
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT DISULFID 220..229
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00460"
FT DISULFID 248..260
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00460"
FT DISULFID 268..277
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00460"
FT DISULFID 314..323
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00460"
FT DISULFID 326..340
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00460"
FT DISULFID 368..377
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00460"
FT DISULFID 419..428
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00460"
SQ SEQUENCE 594 AA; 62354 MW; 4D829285F5B5EE5F CRC64;
MNGGAERAMR SLRSLGGLAL LCCAAAAAAS AVSPENVTGG GGAAGQVDAS PGPGLRGEPS
YTFPKATAPT AQARRTGPPR TTVRRPLAAS SSTQSLENTA LRETAGPAST TFQAPLGPSP
TTPSAVERTS ATPPAPTRPA PTTLSTTTGP APTTPVATTV PAPTTPRTPT PVLPSSSSVL
PTPPATKGPS PPPPEYVCNC SVVGSLDVNR CNQTTGQCEC QPGYQGLLCE TCKEGFYLNH
TSGLCLPCDC SPHGALSTLC NSSGKCQCKV GVIGSSCDQC QDGYFGFSKN GCFPCQCNNR
STSCDALTGA CLNCQENSKG NHCEKCKEGF YQSPDATKEC LRCPCSAVTS TGSCSIKSGK
LEPECDQCKD GYIGQNCNTC QNGYYNFDSI CRKCQCHGHV DPDKTPKICK PESGECINCL
HNTTGFWCEN CLEGYAQDLE GNCIKKEVIV PTPEGSTILV SNASLTTSVP SPIINSTFTP
TTLQTILSTS ENSTSALADV SWTQFNIIIL TVIIIVVVLL MGFVGAVYMY REYQNRKLNA
PFWTIELKED NISFSSYHDS IPNADVSGLL EDDGNEVAPN GQLTLTTPIH NYKA
//
