ID A0A2K6JNV8_RHIBE Unreviewed; 1227 AA.
AC A0A2K6JNV8;
DT 28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT 28-MAR-2018, sequence version 1.
DT 24-JAN-2024, entry version 26.
DE SubName: Full=PTPRF interacting protein alpha 1 {ECO:0000313|Ensembl:ENSRBIP00000000711.1};
GN Name=PPFIA1 {ECO:0000313|Ensembl:ENSRBIP00000000711.1};
OS Rhinopithecus bieti (Black snub-nosed monkey) (Pygathrix bieti).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Cercopithecidae; Colobinae; Rhinopithecus.
OX NCBI_TaxID=61621 {ECO:0000313|Ensembl:ENSRBIP00000000711.1, ECO:0000313|Proteomes:UP000233180};
RN [1] {ECO:0000313|Ensembl:ENSRBIP00000000711.1, ECO:0000313|Proteomes:UP000233180}
RP NUCLEOTIDE SEQUENCE.
RA Wu, C.-I. and Zhang, Y.;
RT "Genome of Rhinopithecus bieti.";
RL Submitted (JUN-2016) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSRBIP00000000711.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the liprin family. Liprin-alpha subfamily.
CC {ECO:0000256|ARBA:ARBA00007026}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR RefSeq; XP_017742602.1; XM_017887113.1.
DR AlphaFoldDB; A0A2K6JNV8; -.
DR Ensembl; ENSRBIT00000004109.1; ENSRBIP00000000711.1; ENSRBIG00000000739.1.
DR GeneID; 108538811; -.
DR CTD; 8500; -.
DR GeneTree; ENSGT01050000244900; -.
DR OrthoDB; 2906732at2759; -.
DR Proteomes; UP000233180; Unplaced.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProt.
DR CDD; cd09562; SAM_liprin-alpha1_2_3_4_repeat1; 1.
DR CDD; cd09565; SAM_liprin-alpha1_2_3_4_repeat2; 1.
DR CDD; cd09568; SAM_liprin-alpha1_2_3_4_repeat3; 1.
DR Gene3D; 1.10.150.50; Transcription Factor, Ets-1; 3.
DR InterPro; IPR029515; Liprin.
DR InterPro; IPR037620; Liprin-alpha_SAM_rpt_1.
DR InterPro; IPR037621; Liprin-alpha_SAM_rpt_2.
DR InterPro; IPR037622; Liprin-alpha_SAM_rpt_3.
DR InterPro; IPR001660; SAM.
DR InterPro; IPR013761; SAM/pointed_sf.
DR PANTHER; PTHR12587; LAR INTERACTING PROTEIN LIP -RELATED PROTEIN; 1.
DR PANTHER; PTHR12587:SF15; LIPRIN-ALPHA-1; 1.
DR Pfam; PF00536; SAM_1; 1.
DR Pfam; PF07647; SAM_2; 1.
DR SMART; SM00454; SAM; 3.
DR SUPFAM; SSF47769; SAM/Pointed domain; 3.
DR PROSITE; PS50105; SAM_DOMAIN; 3.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000233180}.
FT DOMAIN 903..969
FT /note="SAM"
FT /evidence="ECO:0000259|PROSITE:PS50105"
FT DOMAIN 995..1052
FT /note="SAM"
FT /evidence="ECO:0000259|PROSITE:PS50105"
FT DOMAIN 1076..1145
FT /note="SAM"
FT /evidence="ECO:0000259|PROSITE:PS50105"
FT REGION 1..33
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 224..244
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 451..471
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 676..880
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1188..1227
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 97..131
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 266..388
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 494..542
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 224..239
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 706..724
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 774..792
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 793..818
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 856..870
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1227 AA; 138334 MW; 3A841F86C0F241A3 CRC64;
MMCEVMPTIS EAEGPPGGGG SHGSGSPSQP DADSHFEQLM VSMLEERDRL LDTLRETQET
LALTQGKLHE VGHERDSLQR QLNTALPQEF AALTKELNVC REQLLEREEE IAELKAERNN
TRLLLEHLEC LVSRHERSLR MTVVKRQAQS PAGVSSEVEV LKALKSLFEH HKALDEKVRE
RLRVALERCS LLEEELGATH KELMILKEQN SQKKTLTDGV LDINHEQENT PSTNGKRSSD
GSLSHEEDLA KVIELQEIIS KQSREQSQMK ERLASLSSHV TELEEDLDTA RKDLIKSEEM
NTKLQGDVRE AMAQKEDMEE RITTLEKRYL AAQREATSVH DLNDKLENEI ANKDSMHRQT
EDKNRQLQER LELAEQKLQQ TLRKAETLPE VEAELAQRVA ALSKSDLLSS GSSAAKEAKL
LELTSKLRKA EERHGNIEER LRQMEAQLEE KNQELQRARQ REKMNEEHNK RLSDTVDKLL
SESNERLQLH LKERMAALED KNSLLREVEN AKKQLEETQH DKDQLVLNIE ALRAELDQMR
LRGASLHHGR PHLGSVPDFR FPMADGHTDS YSTSAVLRRP QKGRLAALRD EPSKVQTLNE
QDWERAQQAS VLANVAQAFE SDADVSDGED DRDTLLSSVD LLSPSGQADA HTLAMMLQEQ
LDAINKEIRL IQEEKENTEQ RAEEIESRVG SGSLDNLGRF RSMSSIPPYP ASSLASSSPP
GSGRSTPRRI PHSPAREVDR LGVMTLLPPS REEVRDDKTT IKCETSPPSS PRALRLDRLH
KGALHTVSQE DIRDIRNSTG SQDGPVSNPS SSNSSQDSLH KAPKKKGIKS SIGRLFGKKE
KGRPGQTGKE ALGQAGVSET DNSSQDALGL SKLGGQAEKN RKLQKKHELL EEARRQGLPF
AQWDGPTVVV WLELWVGMPA WYVAACRANV KSGAIMSALS DTEIQREIGI SNPLHRLKLR
LAIQEIMSLT SPSAPPTSRT TLAYGDMNHE WIGNEWLPSL GLPQYRSYFM ECLVDARMLD
HLTKKDLRGQ LKMVDSFHRN SFQCGIMCLR RLNYDRKELE RKREESQSEI KDVLVWSNDR
VIRWILSIGL KEYANNLIES GVHGALLALD ETFDFSALAL LLQIPTQNTQ ARAVLEREFN
NLLVMGTDRR FDEDDDKSFR RAPSWRKKFR PKDIRGLAAG SAETLPANFR VTSSMSSPSM
QPKKMQMDGN VSGTQRLDSA TVRTYSC
//
