ID A0A2K6JQ34_RHIBE Unreviewed; 628 AA.
AC A0A2K6JQ34;
DT 28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT 28-MAR-2018, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE SubName: Full=Zinc finger SWIM-type containing 2 {ECO:0000313|Ensembl:ENSRBIP00000001125.1};
GN Name=ZSWIM2 {ECO:0000313|Ensembl:ENSRBIP00000001125.1};
OS Rhinopithecus bieti (Black snub-nosed monkey) (Pygathrix bieti).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Cercopithecidae; Colobinae; Rhinopithecus.
OX NCBI_TaxID=61621 {ECO:0000313|Ensembl:ENSRBIP00000001125.1, ECO:0000313|Proteomes:UP000233180};
RN [1] {ECO:0000313|Ensembl:ENSRBIP00000001125.1, ECO:0000313|Proteomes:UP000233180}
RP NUCLEOTIDE SEQUENCE.
RA Wu, C.-I. and Zhang, Y.;
RT "Genome of Rhinopithecus bieti.";
RL Submitted (JUN-2016) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSRBIP00000001125.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR AlphaFoldDB; A0A2K6JQ34; -.
DR STRING; 61621.ENSRBIP00000001125; -.
DR Ensembl; ENSRBIT00000006429.1; ENSRBIP00000001125.1; ENSRBIG00000005901.1.
DR GeneTree; ENSGT00390000006826; -.
DR OMA; RNQKWRS; -.
DR Proteomes; UP000233180; Unplaced.
DR GO; GO:0043621; F:protein self-association; IEA:Ensembl.
DR GO; GO:0061630; F:ubiquitin protein ligase activity; IEA:Ensembl.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR GO; GO:1902043; P:positive regulation of extrinsic apoptotic signaling pathway via death domain receptors; IEA:Ensembl.
DR GO; GO:0000209; P:protein polyubiquitination; IEA:Ensembl.
DR CDD; cd16486; mRING-H2-C3H2C2D_ZSWM2; 1.
DR CDD; cd16494; RING-CH-C4HC3_ZSWM2; 1.
DR Gene3D; 3.30.60.90; -; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 2.
DR InterPro; IPR001841; Znf_RING.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR InterPro; IPR000433; Znf_ZZ.
DR InterPro; IPR043145; Znf_ZZ_sf.
DR InterPro; IPR039903; Zswim2.
DR PANTHER; PTHR21540:SF0; E3 UBIQUITIN-PROTEIN LIGASE ZSWIM2; 1.
DR PANTHER; PTHR21540; RING FINGER AND SWIM DOMAIN-CONTAINING PROTEIN 2; 1.
DR Pfam; PF13639; zf-RING_2; 1.
DR Pfam; PF00569; ZZ; 1.
DR SMART; SM00184; RING; 2.
DR SUPFAM; SSF57850; RING/U-box; 3.
DR PROSITE; PS50089; ZF_RING_2; 2.
DR PROSITE; PS01357; ZF_ZZ_1; 1.
DR PROSITE; PS50135; ZF_ZZ_2; 1.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000233180};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00228}.
FT DOMAIN 142..193
FT /note="RING-type"
FT /evidence="ECO:0000259|PROSITE:PS50089"
FT DOMAIN 224..275
FT /note="ZZ-type"
FT /evidence="ECO:0000259|PROSITE:PS50135"
FT DOMAIN 339..380
FT /note="RING-type"
FT /evidence="ECO:0000259|PROSITE:PS50089"
SQ SEQUENCE 628 AA; 71859 MW; DAE37DE8A458B2FF CRC64;
MLRRGYKASE RRRHLSERLS WHQDQALSSS IYLLREMGPT VLLSQILLIF YAFSFKGFLG
NPHVCNCSTF LKGGELCKHI YLPQKSILVS ALQLGLGERE ISDLLQGIHR VQTPQPGTND
HNEHVEEDGY IKQKEIDSED ICSICQELLL EKKLPVTFCR FGCGNSIHIK CMKILANYQS
TSNTSMLKCP LCRKEFAPLK LILEEFKNSS KLVTAAEKER LDKHLGIPCN NCKQFPIEGK
CYKCTECIEY HLCQECFDSC CHLSHTLTFR EKRNQKWRSL EKRTDEAVKY IDTKNEIQEK
MSHFQEKQDQ VYTPKHVVRS LPLQLITKNS KLLAPGYQCL LCLKAFHLGQ HTRLLPCTHK
FHRKCIDNWL FHKCNSCPID GQVIYNPLTW KNSAVNGQAH QSVSNRDIIH LSKQKEPDLF
IPGTGLVLKQ NRLGILPSIP QCNFDKLNTP QSPKDACENI PIDNLCSIQL DNSNSRKLTY
EYKISQHFPR YLQDLPMVSF GKIPSQTFLP PIVHKNIVCP TAMESPCISG KYHTSQSRMT
KGCTCNNHNL KKTPGTKIRE DNKRSTLLPE DFNLIANWST AKLSLSKRYN NCMGEITRKC
SHLSRQPVSH SVNTKGTELS LIIEGVQL
//
