ID A0A2K6JRL1_RHIBE Unreviewed; 3076 AA.
AC A0A2K6JRL1;
DT 28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT 28-MAR-2018, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE SubName: Full=Immunoglobulin like and fibronectin type III domain containing 1 {ECO:0000313|Ensembl:ENSRBIP00000001655.1};
GN Name=IGFN1 {ECO:0000313|Ensembl:ENSRBIP00000001655.1};
OS Rhinopithecus bieti (Black snub-nosed monkey) (Pygathrix bieti).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Cercopithecidae; Colobinae; Rhinopithecus.
OX NCBI_TaxID=61621 {ECO:0000313|Ensembl:ENSRBIP00000001655.1, ECO:0000313|Proteomes:UP000233180};
RN [1] {ECO:0000313|Ensembl:ENSRBIP00000001655.1, ECO:0000313|Proteomes:UP000233180}
RP NUCLEOTIDE SEQUENCE.
RA Wu, C.-I. and Zhang, Y.;
RT "Genome of Rhinopithecus bieti.";
RL Submitted (JUN-2016) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSRBIP00000001655.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
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DR STRING; 61621.ENSRBIP00000001655; -.
DR Ensembl; ENSRBIT00000009127.1; ENSRBIP00000001655.1; ENSRBIG00000008024.1.
DR GeneTree; ENSGT00940000162073; -.
DR OMA; GSEPDFW; -.
DR Proteomes; UP000233180; Unplaced.
DR GO; GO:0005634; C:nucleus; IEA:Ensembl.
DR GO; GO:0030018; C:Z disc; IEA:Ensembl.
DR CDD; cd00063; FN3; 4.
DR Gene3D; 2.60.40.10; Immunoglobulins; 11.
DR InterPro; IPR003961; FN3_dom.
DR InterPro; IPR036116; FN3_sf.
DR InterPro; IPR007110; Ig-like_dom.
DR InterPro; IPR036179; Ig-like_dom_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR013098; Ig_I-set.
DR InterPro; IPR003599; Ig_sub.
DR InterPro; IPR003598; Ig_sub2.
DR InterPro; IPR040849; MyBP-C_THB.
DR PANTHER; PTHR13817:SF73; PROTEIN SIDEKICK HOMOLOG; 1.
DR PANTHER; PTHR13817; TITIN; 1.
DR Pfam; PF00041; fn3; 4.
DR Pfam; PF07679; I-set; 5.
DR Pfam; PF18362; THB; 1.
DR SMART; SM00060; FN3; 4.
DR SMART; SM00409; IG; 5.
DR SMART; SM00408; IGc2; 4.
DR SUPFAM; SSF49265; Fibronectin type III; 2.
DR SUPFAM; SSF48726; Immunoglobulin; 6.
DR PROSITE; PS50853; FN3; 4.
DR PROSITE; PS50835; IG_LIKE; 5.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Immunoglobulin domain {ECO:0000256|ARBA:ARBA00023319};
KW Reference proteome {ECO:0000313|Proteomes:UP000233180};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT DOMAIN 29..119
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 2267..2364
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 2373..2462
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 2471..2567
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 2571..2670
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 2672..2767
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 2771..2855
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 2868..2962
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 2976..3070
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT REGION 61..81
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 403..625
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 768..952
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 981..1091
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1128..1403
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1553..1608
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1697..1718
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1800..1899
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1923..2214
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2228..2280
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 188..215
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 65..81
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 409..436
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 460..474
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 573..598
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 934..948
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1361..1379
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1818..1832
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1960..1979
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2124..2150
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2167..2181
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2228..2262
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 3076 AA; 320877 MW; 17EA747179301C26 CRC64;
MAGKFRKSHI PGVSIWQLVE EIPEGCSTPD FEQKPVTLAL PEGKNAIFRA VVCGEPRPEV
HWQNSKGDLS DSSKYKISSS PGSKEHVLQI SKLTGEDTDL YRCTAVNMYG EATCSARLTV
IEVGFRKNRK RHKEPQEDLR KELMDFRKLL KKRAPPAPEK KIDLEQVWQL LMTADRKDYE
QICMKYGIVD YRGMLRRLQE MKKEQEDKMA QYINAISSLR HIRVTKDGIA KFDLELDLKD
SQSKIYLYKD GEMIPYGFNN QTKHCLRRLG KRYEFQIQDL RPEDSGIYQV KVEDAVVFST
ELEASAIPPR VVVPLAETHC EEHGDAVFKC TFSSPCPSAA WHFRHRLLHA SDKYEVSVSP
DGLTHQLVVR GARFSDMGPY SLGTGPYTSS AWLVVEAGKD KDLQSTSADH QLQRRGAQAS
GAEESGSINS QGEKFGEQDP SGGALEGAGM SSGFQHIASP DRDGRGRHGY SLMEDKGAAD
SAWGPGQEGE GFLEAEGSRV TLPRERQSGR EGGWAESLAE RPHLQGESSE SGLGLPEKQQ
QDRGRDSNGD ECWRTAGGWE AESSLLRAGG LGSSREGKEH RGDSGRQLDR HAPEQLWDAQ
LRPERGNSDL QGYQSDPVGS WPRGKQIKIS QGDSLVEMDR EDAPSRERGR GVVVWGSGTG
LGEAGDSNGA GGPGTLEFTG GRGSGSKAGM GPESWGSQGG RDTDYGEAWG YWGSGEFLGQ
TFGGKDFQEP SISGGRKFLL GDGSPEIKAK DSLQEADGLC RGESVVGGSA YKTGPGGPGD
PRGCEGGLQK LRGRDGQEPA WASGEIGDDP RSFQSSQEWT ADHRAAGGVG RIQPKGTSPW
EDTPSSLRKT GAHYGSGVLG PSGGQEGMGG TQVAGLTESG QGVDARSRGL SRSPGVGAQG
SGGILGDTEV LRGPGSIGSE PDFWNGSGSS RVKGPRGYKD DLEGPGRMES RYEGGLGYSR
GIGPKSRAGY SYGSGVPGEM GSGHGAGCRV SPRAPVGMES EEGGAYRSGS GVPGGVWSGN
EDSGPAGGGS GRVASLKNGS GGPDGAPVGD IRNWASARQG GMGRRGGHHS DGGLGSPEMT
GSVGRGGLKA PGVVETVGMG CVEAEPESSE RIRPWSQTGF RASEALGAFG EGGYEDGSGG
PEAMEPRSLR AGSKVGEGDG TRCPGARASG AGTGYRDDTR HPEALAPHTG AASESQWAYG
ADNVLGYEDG SELPGPQGTG VRTAYGGGSR GLGRRSTGPE GEAGFRDSSG DLQGMGSADG
PGCRKGIGSS GEMGSVDKEG YREDLGTPEN MGSGSKAAYR DGVGGSGAMG SMDEADYRKD
LGAPEGISSG SKADYSGGLQ GSREMGSESN ADYRGGLKGS REMGPMDEAD YRKDSGVPEG
MGADYRGGLR GPGEMGSVDE SGHRNGIGGY GEMGSGYRED VGAPEGMGTG SKAGYSNGLR
GSGEMRSVDE ADYRKNLGAP EGMDSGSKAG YRGGLRGSGK MGLMDEAGSR KDLGVSEGVG
SGSKAGFRDG LGGSGEMGSV GGAGYREGLF RDGLGGSGEM GSVDEAGYRK DLGAPKGMGS
GSKAGFRDGL GGSGEMGSVD EAGYRKDLGA PKGMGSGSKA GFRDGLGGSG EMGSVDEAGY
RKDLGAPKGM DSGSYIDYRN GLGGSGKISS GGEAGYKNVL GGSGRIPLGS EAGSRGSLED
SGYILSRSEA GCGQGFGGTG GMGSGSEVSY RGGSGGSGEM GPEGEMGYGD GSGRLGVPGS
LAGMGHEAGP RGHKAMGHRS GYWVASEGGT SCKDGPERAR ETGLVDGAGP GVESGMAGML
GTAGGMAHRD SSRGPGVLGS QGGPQTLSDE RGSTKDLGGY GTSGIPEALE AAGAKGKLDV
KEWQDSSGTP GSSRDRGAPR AKDRSPDQAG IMGSSGFLDG KGAVEGETWA GMAALGSGHE
KDIWKAGPGM TDRGRVAGQG RLASQRGRDS LLGGRRIGSG SSAGTGQDLD SSSMPGERGK
STSGPADGLG MSNAWAPDWE NQGFSRGSIG AGKQPAGSRA SGSLREKDAA FGGIHEGPGG
FKGREGAPGQ EAAGGCRSPW SLDSKGSGPG RGSSGGAEDS GILGKGNSTE QGNAVIPKPG
ESGPQGAWNG LDGPFGRRAS GDRSGGTQDL SSQLGKGQRG GKTSLGGQGS LEAKNGEVQG
PGALKEDEVQ GAEETGRSDR SSLRSRSQAQ SGAEVGGGKR RGADEAGSMG WQSMGENRGC
LEEMLNEDQS REPPGHLGSR RGGKDGRLDI YGERRDATRS STSRYKPDTG SFSKETRGPI
GHFSQGLADM KVQQGEAATL SCTLTSDLGP GTWFKDGVKL TAQDGVIFKQ DGLVHSLFIA
RVQGTQAGRY TFVAGDQQSE ATLTVQDSPT IAPDVTEKLR EPLVVKAGKP VTVKIPFQSH
LPVQAAWRKD GAKVVGSGDK EAQVDLGDGY TRLCLPSTGR KDSGQYSVTL RSEGGSVQAE
LTLQVIDKPD PPQGPMEVQD CHRAGVCLRW RPPRDDGGQP VECYLVERRQ AGRSTWLKVG
EAPADSTTFT DAHVEPGRKY AFRVRAVTSE GAGEALESEE TLVAPEALPK APSAPAILSA
SSQGITLTWT APRGPGSAHI LGYLIERRKK GSNTWTAVND QPVPERRWTV ADVRQGCQYE
FRVTAVAPSG PGEPGPPSDA VFARDPMRPP GPVRNLQVTD TSNTSLTLSW AGPDTNDGDE
AQGYVVELCG SDSLQWFPCH AGTVPVTSYT AKGLRPGEGY FVRVTAVNEG GQSQPTALDT
LVQAMPVTVC PKFLVDSSTK DLLTVKVGDT VRVPISFEAV PMPEVTWLKD GLPLPKRSVT
VTKDGLTQLL IPVAGLSDSG LYTVVLRTLQ GKEVAHSFRI RVAACPQAPG PIHLQENVPG
TVTAEWEPSP DEAWGVPLHY AVFTRSSAHG PWREAADRIH TNRFTLLGVL PGHEYHFRVV
AKNEVGASKP SYTSQPWCIP RQRDKFTVKA QSYREPDLSQ KPRFLVGLRS HLLPQGCECC
MSCAVQGSPR PHVTWFKNDR SLEGNPAVYS TDLMGVCSLT IPSVSLKDSG EYKAVAENTL
GQAVSTATLI VIEPSA
//
