ID   A0A2K6JRR1_RHIBE        Unreviewed;       833 AA.
AC   A0A2K6JRR1;
DT   28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT   28-MAR-2018, sequence version 1.
DT   27-MAR-2024, entry version 21.
DE   RecName: Full=Tetratricopeptide repeat protein 27 {ECO:0000256|ARBA:ARBA00024124};
GN   Name=TTC27 {ECO:0000313|Ensembl:ENSRBIP00000001700.1};
OS   Rhinopithecus bieti (Black snub-nosed monkey) (Pygathrix bieti).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC   Cercopithecidae; Colobinae; Rhinopithecus.
OX   NCBI_TaxID=61621 {ECO:0000313|Ensembl:ENSRBIP00000001700.1, ECO:0000313|Proteomes:UP000233180};
RN   [1] {ECO:0000313|Ensembl:ENSRBIP00000001700.1, ECO:0000313|Proteomes:UP000233180}
RP   NUCLEOTIDE SEQUENCE.
RA   Wu, C.-I. and Zhang, Y.;
RT   "Genome of Rhinopithecus bieti.";
RL   Submitted (JUN-2016) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Ensembl:ENSRBIP00000001700.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the TTC27 family.
CC       {ECO:0000256|ARBA:ARBA00024020}.
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DR   AlphaFoldDB; A0A2K6JRR1; -.
DR   Ensembl; ENSRBIT00000009412.1; ENSRBIP00000001700.1; ENSRBIG00000008496.1.
DR   GeneTree; ENSGT00500000044929; -.
DR   Proteomes; UP000233180; Unplaced.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 1.
DR   InterPro; IPR011990; TPR-like_helical_dom_sf.
DR   InterPro; IPR013105; TPR_2.
DR   InterPro; IPR019734; TPR_repeat.
DR   InterPro; IPR044244; TTC27/Emw1.
DR   PANTHER; PTHR16193:SF0; TETRATRICOPEPTIDE REPEAT PROTEIN 27; 1.
DR   PANTHER; PTHR16193; UNCHARACTERIZED; 1.
DR   Pfam; PF07719; TPR_2; 1.
DR   SMART; SM00028; TPR; 4.
DR   SUPFAM; SSF48452; TPR-like; 1.
DR   PROSITE; PS50005; TPR; 2.
PE   3: Inferred from homology;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000233180};
KW   TPR repeat {ECO:0000256|PROSITE-ProRule:PRU00339};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        412..431
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   REPEAT          517..550
FT                   /note="TPR"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT   REPEAT          551..584
FT                   /note="TPR"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
SQ   SEQUENCE   833 AA;  95640 MW;  EDB2E4AF4D19F64B CRC64;
     MWTPELAILR GFPTEAERQQ WKQEGFVGSE SGSFLQLLLE GNYEAIFLNS VTQNIFNSAT
     TAEEKIDSYL EKQVVTFLDY STDLDTMERQ QLMFLLGVSS LQLFVQSNWT GPSVDLHPQD
     FLSSVLFQQF SEVKGLDAFV LSLLALDGES IYSLTSKPIL LLLARIILVN VRHKLTAIQS
     LPWWTLRCVN IHQHLLEERS PLLFTLAENC IDQVMKLQNL FVDDSGRYLA IQFHLECAYV
     FLYYYEYRKA KDQLNIAKDI SQLQIDLTGA LGKRTRFQEN YVAQLILDVR REGDVLSNCE
     FTPAPTPQEH LTKNLELNDD TILNDIKLAD CEQFQMPDLC AEELAIILGI CMNFQKNNPV
     HKLTEEELLA FTSCLLSQPK FWAIQTSALI LRTKLERGST RRVERAMRQT QVGINVAICV
     FLPTLYSYMF AMNERMRRLL FELGCTSSAL QIFEKLEMWE DVVICYERAG QHGKAEKILR
     QELEKKETPS LYCLLGDVLG DHSCYDKAWE LSRYRSARAQ RSKALLHLRN KEFQECVECF
     ERSVKINPMQ LGVWFSLGCA YLALEDYQGS AKAFQRCVTL EPDNAEAWNN LSTSYIRLKQ
     KVKAFRTLQE ALKCNYEHWQ IWENYILTST DVGEFSEAIK AYHRLLDLRD KYKDVQVLKI
     LVRAVIDGMT DRSGDVTTGL KGKLQELFGR VTSRVTNDGE IWRLYAQVYG NGQSEKPDEN
     EKAFQCLSKA CRCDTQSNCW EKDITSFKEV VQRALGLAHV AIKCSKNKSS PQEAVQMLSS
     VRLNLRGLLS KAKQLFTDVA TGEMSRELAD DITAMDTLVL ELQDLSNQFR NQY
//