ID A0A2K6JWP6_RHIBE Unreviewed; 753 AA.
AC A0A2K6JWP6;
DT 28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT 28-MAR-2018, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE SubName: Full=Protein tyrosine phosphatase domain containing 1 {ECO:0000313|Ensembl:ENSRBIP00000003452.1};
GN Name=PTPDC1 {ECO:0000313|Ensembl:ENSRBIP00000003452.1};
OS Rhinopithecus bieti (Black snub-nosed monkey) (Pygathrix bieti).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Cercopithecidae; Colobinae; Rhinopithecus.
OX NCBI_TaxID=61621 {ECO:0000313|Ensembl:ENSRBIP00000003452.1, ECO:0000313|Proteomes:UP000233180};
RN [1] {ECO:0000313|Ensembl:ENSRBIP00000003452.1, ECO:0000313|Proteomes:UP000233180}
RP NUCLEOTIDE SEQUENCE.
RA Wu, C.-I. and Zhang, Y.;
RT "Genome of Rhinopithecus bieti.";
RL Submitted (JUN-2016) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSRBIP00000003452.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
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DR AlphaFoldDB; A0A2K6JWP6; -.
DR Ensembl; ENSRBIT00000017843.1; ENSRBIP00000003452.1; ENSRBIG00000016174.1.
DR GeneTree; ENSGT00390000004113; -.
DR Proteomes; UP000233180; Unplaced.
DR GO; GO:0004725; F:protein tyrosine phosphatase activity; IEA:InterPro.
DR GO; GO:0008138; F:protein tyrosine/serine/threonine phosphatase activity; IEA:InterPro.
DR GO; GO:0060271; P:cilium assembly; IEA:InterPro.
DR GO; GO:0016311; P:dephosphorylation; IEA:InterPro.
DR CDD; cd14506; PTP_PTPDC1; 1.
DR Gene3D; 3.90.190.10; Protein tyrosine phosphatase superfamily; 1.
DR InterPro; IPR000340; Dual-sp_phosphatase_cat-dom.
DR InterPro; IPR029021; Prot-tyrosine_phosphatase-like.
DR InterPro; IPR049573; PTPDC1_PTP.
DR InterPro; IPR016130; Tyr_Pase_AS.
DR InterPro; IPR003595; Tyr_Pase_cat.
DR InterPro; IPR000387; Tyr_Pase_dom.
DR InterPro; IPR020422; TYR_PHOSPHATASE_DUAL_dom.
DR PANTHER; PTHR23339:SF125; PROTEIN TYROSINE PHOSPHATASE DOMAIN-CONTAINING PROTEIN 1; 1.
DR PANTHER; PTHR23339; TYROSINE SPECIFIC PROTEIN PHOSPHATASE AND DUAL SPECIFICITY PROTEIN PHOSPHATASE; 1.
DR Pfam; PF00782; DSPc; 1.
DR SMART; SM00404; PTPc_motif; 1.
DR SUPFAM; SSF52799; (Phosphotyrosine protein) phosphatases II; 1.
DR PROSITE; PS00383; TYR_PHOSPHATASE_1; 1.
DR PROSITE; PS50056; TYR_PHOSPHATASE_2; 1.
DR PROSITE; PS50054; TYR_PHOSPHATASE_DUAL; 1.
PE 4: Predicted;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Protein phosphatase {ECO:0000256|ARBA:ARBA00022912};
KW Reference proteome {ECO:0000313|Proteomes:UP000233180}.
FT DOMAIN 82..252
FT /note="Tyrosine-protein phosphatase"
FT /evidence="ECO:0000259|PROSITE:PS50054"
FT DOMAIN 167..234
FT /note="Tyrosine specific protein phosphatases"
FT /evidence="ECO:0000259|PROSITE:PS50056"
FT REGION 485..547
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 504..547
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 753 AA; 84406 MW; 1C1831058752AB7B CRC64;
MAAGVLPQNE QPYSTFMNNS KCVANMKGNL ERPTPKYTKV GERLRHVIPG HMACSMACGG
RACKYENPAR WSEQEQAIKG VYSSWVTDNI LAMARPSSEL LEKYHIIDQF LSHGKTIINL
QRPGEHASCG NPLEQESGFT YLPEAFMQAG IYFYNFGWKD YGVASLTTIL DMVKVMTFAL
QEGKVAIHCH AGLGRTGVLI ACYLVFATRM TADQAIIFVR AKRPNSIQTR GQLLCVREFT
QFLTPLRNIF SCCDPKAHAV TLAQYLIRQR HLLHGYEARL LKHVPKIIHL VCKLLLDLAE
NRPVVMKDVS KGPGLSAEIE KTMSEMVTMQ LDKELLRNDS DVSNPSNPTA VAADFDNRGV
IFSNEQEFDP LWKRRNVECL QPLSHLKRRL SYSDSDLKRA ENLLEQGEPP QTVPVQVLVG
HNPRQQKPIG HCYIPQSPEP DLHKEALVRS TLSFWSQSKF GGLEGLKDNG SPIFHGRIIP
KEAQQSRAFS ADVSGPHSPG EPVSPSFANV NKDPNPTHQQ VSHCQCKTHG VGSPGSVRQI
SSTPQRPLDY GSSLKAQFLV EHETQDSNDL AEAASHPTLQ SELSAEARRI LAAKALANLN
ESVEKEELKR KVEMWQKELN SRDGAWERIC GERDPFILCS LMWSWVEQLK EPVITKEDVD
MLVDRRADAA EALFLLEKGQ HQTILCVLHC IVNLQTIPVD VEEAFLAHAI KAFTKVNFDS
ENGPIVYNTL KKIFKHTLEE KRKMTKDGPK PGL
//
