ID A0A2K6JZA4_RHIBE Unreviewed; 756 AA.
AC A0A2K6JZA4;
DT 28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT 28-MAR-2018, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE SubName: Full=Neural cell adhesion molecule 1 {ECO:0000313|Ensembl:ENSRBIP00000004345.1};
GN Name=NCAM1 {ECO:0000313|Ensembl:ENSRBIP00000004345.1};
OS Rhinopithecus bieti (Black snub-nosed monkey) (Pygathrix bieti).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Cercopithecidae; Colobinae; Rhinopithecus.
OX NCBI_TaxID=61621 {ECO:0000313|Ensembl:ENSRBIP00000004345.1, ECO:0000313|Proteomes:UP000233180};
RN [1] {ECO:0000313|Ensembl:ENSRBIP00000004345.1, ECO:0000313|Proteomes:UP000233180}
RP NUCLEOTIDE SEQUENCE.
RA Wu, C.-I. and Zhang, Y.;
RT "Genome of Rhinopithecus bieti.";
RL Submitted (JUN-2016) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSRBIP00000004345.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- FUNCTION: This protein is a cell adhesion molecule involved in neuron-
CC neuron adhesion, neurite fasciculation, outgrowth of neurites, etc.
CC {ECO:0000256|ARBA:ARBA00003000}.
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DR AlphaFoldDB; A0A2K6JZA4; -.
DR Ensembl; ENSRBIT00000021968.1; ENSRBIP00000004345.1; ENSRBIG00000013766.1.
DR GeneTree; ENSGT00940000155743; -.
DR Proteomes; UP000233180; Unplaced.
DR GO; GO:0016020; C:membrane; IEA:InterPro.
DR GO; GO:0007155; P:cell adhesion; IEA:InterPro.
DR CDD; cd00063; FN3; 2.
DR CDD; cd00096; Ig; 1.
DR CDD; cd05865; IgI_1_NCAM-1; 1.
DR CDD; cd05869; IgI_NCAM-1; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 7.
DR InterPro; IPR003961; FN3_dom.
DR InterPro; IPR036116; FN3_sf.
DR InterPro; IPR007110; Ig-like_dom.
DR InterPro; IPR036179; Ig-like_dom_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR013098; Ig_I-set.
DR InterPro; IPR003599; Ig_sub.
DR InterPro; IPR003598; Ig_sub2.
DR InterPro; IPR009138; Neural_cell_adh.
DR PANTHER; PTHR12231; CTX-RELATED TYPE I TRANSMEMBRANE PROTEIN; 1.
DR PANTHER; PTHR12231:SF239; NEURAL CELL ADHESION MOLECULE 1; 1.
DR Pfam; PF00041; fn3; 2.
DR Pfam; PF07679; I-set; 2.
DR Pfam; PF13927; Ig_3; 3.
DR PRINTS; PR01838; NCAMFAMILY.
DR SMART; SM00060; FN3; 2.
DR SMART; SM00409; IG; 5.
DR SMART; SM00408; IGc2; 5.
DR SUPFAM; SSF49265; Fibronectin type III; 1.
DR SUPFAM; SSF48726; Immunoglobulin; 5.
DR PROSITE; PS50853; FN3; 2.
DR PROSITE; PS50835; IG_LIKE; 5.
PE 4: Predicted;
KW Immunoglobulin domain {ECO:0000256|ARBA:ARBA00023319};
KW Reference proteome {ECO:0000313|Proteomes:UP000233180};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT DOMAIN 17..108
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 113..186
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 209..298
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 305..400
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 403..488
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 496..595
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 631..726
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
SQ SEQUENCE 756 AA; 83313 MW; 37DD17A8C3E95D32 CRC64;
VSPPSDCVWT VWGTASLQVD IVPSQGEISV GESKFFLCQV AGDAKDKDIS WFSPNGEKLT
PNQQRISVVW NDDSSSTLTI YNANIDDAGI YKCVVTGEDG SESEATVNVK IFQKLMFKNA
PTPQEFREGE DAVIVCDVVS SLPPTIIWKH KGRDVILKKD VRFIVLSNNY LQIRGIKKTD
EGTYRCEGRI LARGEINFKD IQVVVNVPPT IQARQNIVNA TANLGQSVTL VCDAEGFPEP
TMSWTKDGEQ IEQEEDDEKY IFSDDSSQLT IKKVDKNDEA EYICIAENKA GEQDATIHLK
VFAKPKITYV ENQTAMELEE QVTLTCEASG DPIPSITWRT STRNISSEEK TLDGHMVVRS
HARVSSLTLK SIQYTDAGEY ICTASNTIGQ DSQSMYLEVQ YAPKLQGPVA VYTWEGNQVN
ITCEVFAYPS ATISWFRDGQ LLPSSNYSNI KIYNTPSASY LEVTPDSEND FGNYNCTAVN
RIGQESLEFI LVQADTPSSP SIDQVEPYSS TAQVQFDEPE ATGGVPILKY KAEWRAVGEE
VWHSKWYDAK EASMEGIVTI VGLKPETTYA VRLAALNGKG LGEISAASEF KTQPFNLSPF
SASPFCAFSV CHVSIATWPL PALATTEPAR EPSAPKLEGQ MGEDGNSIKV NLIKQDDGGS
PIRHYLVRYR ALSSEWKPEI RLPSGSDHVM LKSLDWNAEY EVYVVAENQQ GKSKAAHFVF
RTSAQPTAIP ATLGGSSASY TFVSLLFSAV TLLLLC
//
