ID A0A2K6K0B3_RHIBE Unreviewed; 316 AA.
AC A0A2K6K0B3;
DT 28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT 28-MAR-2018, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE RecName: Full=DNA-directed RNA polymerase III subunit RPC6 {ECO:0000256|PIRNR:PIRNR028763};
DE Short=RNA polymerase III subunit C6 {ECO:0000256|PIRNR:PIRNR028763};
GN Name=POLR3F {ECO:0000313|Ensembl:ENSRBIP00000004700.1};
OS Rhinopithecus bieti (Black snub-nosed monkey) (Pygathrix bieti).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Cercopithecidae; Colobinae; Rhinopithecus.
OX NCBI_TaxID=61621 {ECO:0000313|Ensembl:ENSRBIP00000004700.1, ECO:0000313|Proteomes:UP000233180};
RN [1] {ECO:0000313|Ensembl:ENSRBIP00000004700.1, ECO:0000313|Proteomes:UP000233180}
RP NUCLEOTIDE SEQUENCE.
RA Wu, C.-I. and Zhang, Y.;
RT "Genome of Rhinopithecus bieti.";
RL Submitted (JUN-2016) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSRBIP00000004700.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- FUNCTION: DNA-dependent RNA polymerase catalyzes the transcription of
CC DNA into RNA using the four ribonucleoside triphosphates as substrates.
CC Specific peripheric component of RNA polymerase III which synthesizes
CC small RNAs, such as 5S rRNA and tRNAs. {ECO:0000256|PIRNR:PIRNR028763}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123,
CC ECO:0000256|PIRNR:PIRNR028763}.
CC -!- SIMILARITY: Belongs to the eukaryotic RPC34/RPC39 RNA polymerase
CC subunit family. {ECO:0000256|ARBA:ARBA00011038,
CC ECO:0000256|PIRNR:PIRNR028763}.
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DR RefSeq; XP_017719204.1; XM_017863715.1.
DR AlphaFoldDB; A0A2K6K0B3; -.
DR STRING; 61621.ENSRBIP00000004700; -.
DR Ensembl; ENSRBIT00000023577.1; ENSRBIP00000004700.1; ENSRBIG00000021268.1.
DR GeneID; 108523188; -.
DR KEGG; rbb:108523188; -.
DR CTD; 10621; -.
DR GeneTree; ENSGT00390000009679; -.
DR OMA; VGTTKKC; -.
DR OrthoDB; 930780at2759; -.
DR Proteomes; UP000233180; Unplaced.
DR GO; GO:0005666; C:RNA polymerase III complex; IEA:UniProtKB-UniRule.
DR GO; GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:Ensembl.
DR GO; GO:0003690; F:double-stranded DNA binding; IEA:Ensembl.
DR GO; GO:0045089; P:positive regulation of innate immune response; IEA:Ensembl.
DR GO; GO:0032728; P:positive regulation of interferon-beta production; IEA:Ensembl.
DR GO; GO:0006383; P:transcription by RNA polymerase III; IEA:UniProtKB-UniRule.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 2.
DR InterPro; IPR007832; RNA_pol_Rpc34.
DR InterPro; IPR016049; RNA_pol_Rpc34-like.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR12780:SF1; DNA-DIRECTED RNA POLYMERASE III SUBUNIT RPC6; 1.
DR PANTHER; PTHR12780; RNA POLYMERASE III DNA DIRECTED , 39KD SUBUNIT-RELATED; 1.
DR Pfam; PF05158; RNA_pol_Rpc34; 1.
DR PIRSF; PIRSF028763; RNA_pol_Rpc34; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 2.
PE 3: Inferred from homology;
KW DNA-directed RNA polymerase {ECO:0000256|PIRNR:PIRNR028763};
KW Nucleus {ECO:0000256|PIRNR:PIRNR028763};
KW Reference proteome {ECO:0000313|Proteomes:UP000233180};
KW Transcription {ECO:0000256|ARBA:ARBA00023163,
KW ECO:0000256|PIRNR:PIRNR028763}.
SQ SEQUENCE 316 AA; 35657 MW; 49B12D80D00A65ED CRC64;
MAEVKVKVQP PDADPVEIEN RIIELCHQFP HGITDQVIQN EMPHIEAQQR AVAINRLLSM
GQLDLLRSNT GLLYRIKDSQ NAGKMKGSDN QEKLVYQIIE DAGNKGIWSR DIRYKSNLPL
TEINKILKNL ESKKLIKAVK SVAASKKKVY MLYNLQPDRS VTGGAWYSDQ DFESEFVEVL
NQQCFKFLQS KAETARESKQ NPMIQRNSSF ASSHEVWKYI CELGISKVEL SMEDIETILN
TLIYDGKVEM TIIAAKEGTV GSVDGHMKLY RAVSPIIPPT GLVRAPCGLC PVFDDCHEGG
EISPSNCIYM TEWLEF
//
