ID   A0A2K6K8Y8_RHIBE        Unreviewed;       383 AA.
AC   A0A2K6K8Y8;
DT   28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT   28-MAR-2018, sequence version 1.
DT   24-JAN-2024, entry version 26.
DE   RecName: Full=Transcription factor {ECO:0000256|PIRNR:PIRNR009404};
GN   Name=TFDP2 {ECO:0000313|Ensembl:ENSRBIP00000007740.1};
OS   Rhinopithecus bieti (Black snub-nosed monkey) (Pygathrix bieti).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC   Cercopithecidae; Colobinae; Rhinopithecus.
OX   NCBI_TaxID=61621 {ECO:0000313|Ensembl:ENSRBIP00000007740.1, ECO:0000313|Proteomes:UP000233180};
RN   [1] {ECO:0000313|Ensembl:ENSRBIP00000007740.1, ECO:0000313|Proteomes:UP000233180}
RP   NUCLEOTIDE SEQUENCE.
RA   Wu, C.-I. and Zhang, Y.;
RT   "Genome of Rhinopithecus bieti.";
RL   Submitted (JUN-2016) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Ensembl:ENSRBIP00000007740.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|PIRNR:PIRNR009404,
CC       ECO:0000256|RuleBase:RU003796}.
CC   -!- SIMILARITY: Belongs to the E2F/DP family.
CC       {ECO:0000256|ARBA:ARBA00010940, ECO:0000256|PIRNR:PIRNR009404,
CC       ECO:0000256|RuleBase:RU003796}.
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DR   AlphaFoldDB; A0A2K6K8Y8; -.
DR   Ensembl; ENSRBIT00000031342.1; ENSRBIP00000007740.1; ENSRBIG00000027759.1.
DR   GeneTree; ENSGT00940000157909; -.
DR   Proteomes; UP000233180; Unplaced.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0005667; C:transcription regulator complex; IEA:InterPro.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0051726; P:regulation of cell cycle; IEA:InterPro.
DR   GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR   CDD; cd14458; DP_DD; 1.
DR   Gene3D; 1.20.140.80; Transcription factor DP; 1.
DR   Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR   InterPro; IPR037241; E2F-DP_heterodim.
DR   InterPro; IPR003316; E2F_WHTH_DNA-bd_dom.
DR   InterPro; IPR038168; TF_DP_C_sf.
DR   InterPro; IPR014889; Transc_factor_DP_C.
DR   InterPro; IPR015648; Transcrpt_fac_DP.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   PANTHER; PTHR12548; TRANSCRIPTION FACTOR DP; 1.
DR   PANTHER; PTHR12548:SF5; TRANSCRIPTION FACTOR DP-2; 1.
DR   Pfam; PF08781; DP; 1.
DR   Pfam; PF02319; E2F_TDP; 1.
DR   PIRSF; PIRSF009404; Transcription_factor_DP; 1.
DR   SMART; SM01138; DP; 1.
DR   SMART; SM01372; E2F_TDP; 1.
DR   SUPFAM; SSF144074; E2F-DP heterodimerization region; 1.
DR   SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
PE   3: Inferred from homology;
KW   DNA-binding {ECO:0000256|PIRNR:PIRNR009404, ECO:0000256|RuleBase:RU003796};
KW   Nucleus {ECO:0000256|PIRNR:PIRNR009404, ECO:0000256|RuleBase:RU003796};
KW   Reference proteome {ECO:0000313|Proteomes:UP000233180};
KW   Transcription {ECO:0000256|PIRNR:PIRNR009404,
KW   ECO:0000256|RuleBase:RU003796};
KW   Transcription regulation {ECO:0000256|PIRNR:PIRNR009404,
KW   ECO:0000256|RuleBase:RU003796}.
FT   DOMAIN          63..145
FT                   /note="E2F/DP family winged-helix DNA-binding"
FT                   /evidence="ECO:0000259|SMART:SM01372"
FT   DOMAIN          152..296
FT                   /note="Transcription factor DP C-terminal"
FT                   /evidence="ECO:0000259|SMART:SM01138"
FT   REGION          346..383
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        346..363
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        367..383
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   383 AA;  42670 MW;  436CE064EC61CD5A CRC64;
     ITPQRLTSSG SVLIGSPYTP APAMVTQTHI SEATGWVPGD RKRARKFIDS DFSESKRSKK
     GDKNGKGLRH FSMKVCEKVQ RKGTTSYNEV ADELVSEFTN SNNHLAADSQ AYDQKNIRRR
     VYDALNVLMA MNIISKEKKE IKWIGLPTNS AQECQNLEIE KQRRIERIKQ KRAQLQELLL
     QQIAFKNLVQ RNRQNEQQNQ GPPALNSTIQ LPFIIINTSR KTVIDCSISS DKFEYLFNFD
     NTFEIHDDIE VLKRMGMSFG LESGKCSLED LKLAKSLVPK ALEGYITDIS TGPSWLNQGL
     LLNSTQSVSN LDLTTGATLP QSSVNQGLCL DAEVALATGQ FLAPNSHQSS SAASHCSESR
     GETPCSFNDE DEEDDEEDSS SPE
//