ID   A0A2K6KD41_RHIBE        Unreviewed;       288 AA.
AC   A0A2K6KD41;
DT   28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT   28-MAR-2018, sequence version 1.
DT   27-MAR-2024, entry version 27.
DE   SubName: Full=CD80 molecule {ECO:0000313|Ensembl:ENSRBIP00000009172.1};
GN   Name=CD80 {ECO:0000313|Ensembl:ENSRBIP00000009172.1};
OS   Rhinopithecus bieti (Black snub-nosed monkey) (Pygathrix bieti).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC   Cercopithecidae; Colobinae; Rhinopithecus.
OX   NCBI_TaxID=61621 {ECO:0000313|Ensembl:ENSRBIP00000009172.1, ECO:0000313|Proteomes:UP000233180};
RN   [1] {ECO:0000313|Ensembl:ENSRBIP00000009172.1, ECO:0000313|Proteomes:UP000233180}
RP   NUCLEOTIDE SEQUENCE.
RA   Wu, C.-I. and Zhang, Y.;
RT   "Genome of Rhinopithecus bieti.";
RL   Submitted (JUN-2016) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Ensembl:ENSRBIP00000009172.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004479}; Single-
CC       pass type I membrane protein {ECO:0000256|ARBA:ARBA00004479}.
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DR   RefSeq; XP_017747152.1; XM_017891663.1.
DR   STRING; 61621.ENSRBIP00000009172; -.
DR   Ensembl; ENSRBIT00000032785.1; ENSRBIP00000009172.1; ENSRBIG00000028466.1.
DR   Ensembl; ENSRBIT00000032787.1; ENSRBIP00000009174.1; ENSRBIG00000028466.1.
DR   GeneID; 108541888; -.
DR   CTD; 941; -.
DR   GeneTree; ENSGT00940000162632; -.
DR   OMA; HMTSVML; -.
DR   OrthoDB; 5401666at2759; -.
DR   Proteomes; UP000233180; Unplaced.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0098636; C:protein complex involved in cell adhesion; IEA:Ensembl.
DR   GO; GO:0015026; F:coreceptor activity; IEA:InterPro.
DR   GO; GO:0048018; F:receptor ligand activity; IEA:Ensembl.
DR   GO; GO:0002710; P:negative regulation of T cell mediated immunity; IEA:Ensembl.
DR   GO; GO:0050731; P:positive regulation of peptidyl-tyrosine phosphorylation; IEA:Ensembl.
DR   GO; GO:0042110; P:T cell activation; IEA:Ensembl.
DR   GO; GO:0031295; P:T cell costimulation; IEA:InterPro.
DR   CDD; cd16083; IgC1_CD80; 1.
DR   CDD; cd16086; IgV_CD80; 1.
DR   Gene3D; 2.60.40.10; Immunoglobulins; 2.
DR   InterPro; IPR013162; CD80_C2-set.
DR   InterPro; IPR037676; CD80_IgC.
DR   InterPro; IPR042711; CD80_IgV.
DR   InterPro; IPR007110; Ig-like_dom.
DR   InterPro; IPR036179; Ig-like_dom_sf.
DR   InterPro; IPR013783; Ig-like_fold.
DR   InterPro; IPR003599; Ig_sub.
DR   InterPro; IPR013106; Ig_V-set.
DR   PANTHER; PTHR25466; T-LYMPHOCYTE ACTIVATION ANTIGEN; 1.
DR   PANTHER; PTHR25466:SF4; T-LYMPHOCYTE ACTIVATION ANTIGEN CD80; 1.
DR   Pfam; PF08205; C2-set_2; 1.
DR   Pfam; PF07686; V-set; 1.
DR   SMART; SM00409; IG; 1.
DR   SUPFAM; SSF48726; Immunoglobulin; 2.
DR   PROSITE; PS50835; IG_LIKE; 2.
PE   4: Predicted;
KW   Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW   Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000233180};
KW   Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}.
FT   SIGNAL          1..34
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           35..288
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5015083053"
FT   TRANSMEM        247..268
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          15..118
FT                   /note="Ig-like"
FT                   /evidence="ECO:0000259|PROSITE:PS50835"
FT   DOMAIN          145..230
FT                   /note="Ig-like"
FT                   /evidence="ECO:0000259|PROSITE:PS50835"
SQ   SEQUENCE   288 AA;  33091 MW;  170F47D0E10A13CA CRC64;
     MGHTWRQGIS PSKCPYLKLF QLLVLAGLSH FCSGVIHVTK EVKEVATLSC GHNVSVEELA
     QTRIYWQKEK KMVLTMMSGD MNIWPEYKNR TIFDITNNLS IVILALRPSD EGTYECVVLK
     YEKDAFKREH LAEVMLSVKA DFPTPSISDF EIPPSNIRRI ICSTSGGFPE PHLSWLENGE
     ELNAINTTVS QDPETELYTV SSKLDFNMTT NHSFMCLIKY GHLRVNQTFN WNTPKQEHFP
     DNLLPPWAIT LISVNGIFVI CCLTYCFAPR CRERRRNETL RRESVRPI
//