ID   A0A2K6KEG7_RHIBE        Unreviewed;      1285 AA.
AC   A0A2K6KEG7;
DT   28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT   28-MAR-2018, sequence version 1.
DT   27-MAR-2024, entry version 25.
DE   RecName: Full=Period circadian protein homolog 2 {ECO:0000256|ARBA:ARBA00039684};
DE   AltName: Full=Circadian clock protein PERIOD 2 {ECO:0000256|ARBA:ARBA00042893};
GN   Name=PER2 {ECO:0000313|Ensembl:ENSRBIP00000009652.1};
OS   Rhinopithecus bieti (Black snub-nosed monkey) (Pygathrix bieti).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC   Cercopithecidae; Colobinae; Rhinopithecus.
OX   NCBI_TaxID=61621 {ECO:0000313|Ensembl:ENSRBIP00000009652.1, ECO:0000313|Proteomes:UP000233180};
RN   [1] {ECO:0000313|Ensembl:ENSRBIP00000009652.1, ECO:0000313|Proteomes:UP000233180}
RP   NUCLEOTIDE SEQUENCE.
RA   Wu, C.-I. and Zhang, Y.;
RT   "Genome of Rhinopithecus bieti.";
RL   Submitted (JUN-2016) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Ensembl:ENSRBIP00000009652.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC       Nucleus {ECO:0000256|ARBA:ARBA00004123}.
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DR   Ensembl; ENSRBIT00000033270.1; ENSRBIP00000009652.1; ENSRBIG00000028705.1.
DR   GeneTree; ENSGT00940000156342; -.
DR   OMA; ENCSMGR; -.
DR   Proteomes; UP000233180; Unplaced.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   CDD; cd00130; PAS; 1.
DR   Gene3D; 3.30.450.20; PAS domain; 2.
DR   InterPro; IPR000014; PAS.
DR   InterPro; IPR035965; PAS-like_dom_sf.
DR   InterPro; IPR013655; PAS_fold_3.
DR   InterPro; IPR048814; Per1-3_PAS-A.
DR   InterPro; IPR022728; Period_circadian-like_C.
DR   PANTHER; PTHR11269; PERIOD CIRCADIAN PROTEIN; 1.
DR   PANTHER; PTHR11269:SF9; PERIOD CIRCADIAN PROTEIN HOMOLOG 2; 1.
DR   Pfam; PF08447; PAS_3; 1.
DR   Pfam; PF21353; Per3-like_PAS-A; 1.
DR   Pfam; PF12114; Period_C; 1.
DR   SMART; SM00091; PAS; 2.
DR   SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 1.
DR   PROSITE; PS50112; PAS; 1.
PE   4: Predicted;
KW   Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW   Reference proteome {ECO:0000313|Proteomes:UP000233180}.
FT   DOMAIN          346..389
FT                   /note="PAS"
FT                   /evidence="ECO:0000259|PROSITE:PS50112"
FT   REGION          1..78
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          473..546
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          650..677
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          796..863
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          995..1016
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          1047..1080
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          1105..1137
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          1260..1285
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        28..55
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        477..503
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        504..544
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        798..813
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1265..1285
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1285 AA;  140057 MW;  20D4C58C94E7FBB3 CRC64;
     MNGYTEFSPS PSNPTKEPME PQPSQVPLQE DVDMSSGSSG HETNENCSTG RDSQGSDCDD
     SGKELGMLVE PPDAHQSPDA FSLMITKSEH NPSTSGCSSD QSSKVDTHKE LIKTLKELKV
     HLPADKKAKG KASTLATLKY ALRSVKQVKA NEEYYQLLMS SEGHPCGSDV PSYTVEEMES
     VTSEHIVKNA DMFAVAVSLV SGKILYISDQ VASIFHYKRD AFSDAKFVEF LAPHDVGVFH
     SFTSPYKLPL WSVCSGADSF TQECMEEKSF FCRVSVGKSH ENEIRYHPFR MTPYLVKVRE
     QQGAESQLCC LLLAERVHSG YEAPRIPPEK RIFTTTHTPN CLFQDVDERA VPLLGYLPQD
     LIETPVLVQL HPSDRPLMLA IHKKILQSGG QPFDYSPIRF RTQNGEYITL DTSWSSFINP
     WSRKISFIIG RHKVRMGPLN EDVFAAHPCT EEKALHPSIQ ELTEQIHRLL LQPVPHSGSS
     GYGSLGSNGS HEHLMSQTSS SDSNGHEDSH RRRAEIYKNG NKTKNRSHYS HESGEQKKKS
     VTEMRTNPPA EMKAVPAVEK DSLGASFPEE LACKDQPTCS YQQISCLDSV IRYTGTSSRV
     STISRTLPPL VLCGLTRGSC PSHRYLESCN EAATLKRKCE FPANVPTLRS SDKRKATVSP
     GPHAGEAEPP SRVNSRTGVS THLTSLALPG KAESVASLTS QCSYSSTIVH VGDKKPQPEL
     EMVEDAVSGP ESLDCLVGPA LACGLSQEKE PFKKLGLTKE VLAAHTQKEE QSFLQKFKEI
     RKLSIFQSHC HYYLQERSKG QPSEQTAPGL RNTSGIDSPW RKPGKNRKLK SKRVKPRDSS
     ESTGSGGPVP ARPPLVGLNT TAWSPSDTSQ SSCLAVPFPA PVPAYSLPVF PAPGTVAATP
     APPHASFAVP AVPVDLQHQF AVQPPPFPAP LAPVMAFMLP GYCFPSGTPN LPQAFLPSQP
     QFPSHPTVTS EMASASQPEF PSWTSIPRQP CACPATRATP PSAMGRASPP LFQSRSSSPL
     QLNLLQLEEA PEGTGVMGTT GATETAAVGA DCKPGTSRDQ QLKAPLSRDE PSDTQNSDAL
     STSSGLLNLL LNEDLCSASG SAASESLGSG SLGCDTSPSR AGSSDTSHTS KYFGSVDSSE
     NNHKAKMNTG MEESEHFIKC VLQDPIWLLM ADTDSSVMMT YQLPSRNVEA VLKEDREKLR
     LLQKLQPRFT ASQKQELREV HQWVQTGGLP AAIDVAECVY CENKEKGNIC LPYEEDMPSL
     GLSEVSDTKD DENGSPVNHR IEEQT
//