ID   A0A2K6KL17_RHIBE        Unreviewed;       540 AA.
AC   A0A2K6KL17;
DT   28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT   28-MAR-2018, sequence version 1.
DT   24-JAN-2024, entry version 30.
DE   SubName: Full=Extracellular matrix protein 1 {ECO:0000313|Ensembl:ENSRBIP00000011961.1};
GN   Name=ECM1 {ECO:0000313|Ensembl:ENSRBIP00000011961.1};
OS   Rhinopithecus bieti (Black snub-nosed monkey) (Pygathrix bieti).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC   Cercopithecidae; Colobinae; Rhinopithecus.
OX   NCBI_TaxID=61621 {ECO:0000313|Ensembl:ENSRBIP00000011961.1, ECO:0000313|Proteomes:UP000233180};
RN   [1] {ECO:0000313|Ensembl:ENSRBIP00000011961.1, ECO:0000313|Proteomes:UP000233180}
RP   NUCLEOTIDE SEQUENCE.
RA   Wu, C.-I. and Zhang, Y.;
RT   "Genome of Rhinopithecus bieti.";
RL   Submitted (JUN-2016) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Ensembl:ENSRBIP00000011961.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
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DR   RefSeq; XP_017733291.1; XM_017877802.1.
DR   AlphaFoldDB; A0A2K6KL17; -.
DR   STRING; 61621.ENSRBIP00000011961; -.
DR   Ensembl; ENSRBIT00000035650.1; ENSRBIP00000011961.1; ENSRBIG00000029889.1.
DR   GeneID; 108533270; -.
DR   KEGG; rbb:108533270; -.
DR   CTD; 1893; -.
DR   GeneTree; ENSGT00390000006215; -.
DR   OMA; CCRCRSH; -.
DR   OrthoDB; 4577436at2759; -.
DR   Proteomes; UP000233180; Unplaced.
DR   GO; GO:0062023; C:collagen-containing extracellular matrix; IEA:Ensembl.
DR   GO; GO:0005615; C:extracellular space; IEA:Ensembl.
DR   GO; GO:0005134; F:interleukin-2 receptor binding; IEA:Ensembl.
DR   GO; GO:0002020; F:protease binding; IEA:Ensembl.
DR   GO; GO:0002063; P:chondrocyte development; IEA:Ensembl.
DR   GO; GO:0003416; P:endochondral bone growth; IEA:Ensembl.
DR   GO; GO:0006954; P:inflammatory response; IEA:Ensembl.
DR   GO; GO:0030502; P:negative regulation of bone mineralization; IEA:Ensembl.
DR   GO; GO:0001960; P:negative regulation of cytokine-mediated signaling pathway; IEA:Ensembl.
DR   GO; GO:0045766; P:positive regulation of angiogenesis; IEA:Ensembl.
DR   GO; GO:0001938; P:positive regulation of endothelial cell proliferation; IEA:Ensembl.
DR   GO; GO:2000404; P:regulation of T cell migration; IEA:Ensembl.
DR   GO; GO:0006357; P:regulation of transcription by RNA polymerase II; IEA:Ensembl.
DR   GO; GO:0002828; P:regulation of type 2 immune response; IEA:Ensembl.
DR   GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR   Gene3D; 1.10.246.10; -; 3.
DR   InterPro; IPR008605; ECM1.
DR   InterPro; IPR020858; Serum_albumin-like.
DR   PANTHER; PTHR16776; EXTRACELLULAR MATRIX PROTEIN 1; 1.
DR   PANTHER; PTHR16776:SF3; EXTRACELLULAR MATRIX PROTEIN 1; 1.
DR   Pfam; PF05782; ECM1; 1.
DR   SUPFAM; SSF48552; Serum albumin-like; 2.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000233180};
KW   Secreted {ECO:0000256|ARBA:ARBA00022525}; Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL          1..19
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           20..540
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5014318692"
FT   REGION          41..85
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          118..173
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          515..540
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        66..85
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        118..156
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        516..534
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   540 AA;  60582 MW;  2E83F2C92B307403 CRC64;
     MGTTVRAALV LAYLAIASAA SEGGFKATGQ RQLRPEHFQE VGYAAPPSPP LSRSLLMDHP
     DTSQHGPPFE GQSQVQPPPS QEATPIQQEE LLPAQLPAEK EVGPPLSQEA VPLQKELPSL
     QQPNEQKEGT PASFGDQSHS EPESWNAAQH CQQGRSQGGW AHRLDGFPPG RPSPENLNQI
     CLPDRQHVVY GPWNLPQSSY SHLTRQGETL NFLEIGYSRC CHCRSHTNRL ECAKLVWEEA
     MSRFCEAEFS VKTRPHWCCT QQGEARFSCF QEEAPQPHYQ LRACPSHQPA ISSGLELPFP
     PGAPTLDNIK NICHLRRFRS VPRNLPATDP LQRELLALIR LEREFQRCCR QGNNHTCIWK
     AWEDTLDKYC DREYTVKTHH HSCCRHPPSP SRDECFARQA PYPNYDRDIL AIDISRVTPN
     LMGHLCGNQR VLTKHKHIPG LIHNMTARCC DLPFPEQACC AEEEKLTFIN DLCGPRRKFW
     QDPALCCYLS PGDEQVNCFN INYLRNVALV AGDTENTKGQ GEQGSTGGTN IGSTSEPKEE
//