ID A0A2K6KST1_RHIBE Unreviewed; 789 AA.
AC A0A2K6KST1;
DT 28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT 28-MAR-2018, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE SubName: Full=Kinesin associated protein 3 {ECO:0000313|Ensembl:ENSRBIP00000014329.1};
GN Name=KIFAP3 {ECO:0000313|Ensembl:ENSRBIP00000014329.1};
OS Rhinopithecus bieti (Black snub-nosed monkey) (Pygathrix bieti).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Cercopithecidae; Colobinae; Rhinopithecus.
OX NCBI_TaxID=61621 {ECO:0000313|Ensembl:ENSRBIP00000014329.1, ECO:0000313|Proteomes:UP000233180};
RN [1] {ECO:0000313|Ensembl:ENSRBIP00000014329.1, ECO:0000313|Proteomes:UP000233180}
RP NUCLEOTIDE SEQUENCE.
RA Wu, C.-I. and Zhang, Y.;
RT "Genome of Rhinopithecus bieti.";
RL Submitted (JUN-2016) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSRBIP00000014329.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
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DR AlphaFoldDB; A0A2K6KST1; -.
DR STRING; 61621.ENSRBIP00000014329; -.
DR Ensembl; ENSRBIT00000038162.1; ENSRBIP00000014329.1; ENSRBIG00000030912.1.
DR GeneTree; ENSGT00390000003574; -.
DR OMA; MYELNIV; -.
DR Proteomes; UP000233180; Unplaced.
DR GO; GO:0005930; C:axoneme; IEA:Ensembl.
DR GO; GO:0005813; C:centrosome; IEA:Ensembl.
DR GO; GO:0036064; C:ciliary basal body; IEA:Ensembl.
DR GO; GO:0000794; C:condensed nuclear chromosome; IEA:Ensembl.
DR GO; GO:0005783; C:endoplasmic reticulum; IEA:Ensembl.
DR GO; GO:0005794; C:Golgi apparatus; IEA:Ensembl.
DR GO; GO:0016939; C:kinesin II complex; IEA:Ensembl.
DR GO; GO:1990075; C:periciliary membrane compartment; IEA:Ensembl.
DR GO; GO:0032391; C:photoreceptor connecting cilium; IEA:Ensembl.
DR GO; GO:0001917; C:photoreceptor inner segment; IEA:Ensembl.
DR GO; GO:0001750; C:photoreceptor outer segment; IEA:Ensembl.
DR GO; GO:0005876; C:spindle microtubule; IEA:Ensembl.
DR GO; GO:0120170; F:intraciliary transport particle B binding; IEA:Ensembl.
DR GO; GO:0019894; F:kinesin binding; IEA:Ensembl.
DR GO; GO:0019903; F:protein phosphatase binding; IEA:Ensembl.
DR GO; GO:0010659; P:cardiac muscle cell apoptotic process; IEA:Ensembl.
DR GO; GO:0007017; P:microtubule-based process; IEA:Ensembl.
DR GO; GO:0010667; P:negative regulation of cardiac muscle cell apoptotic process; IEA:Ensembl.
DR GO; GO:0007406; P:negative regulation of neuroblast proliferation; IEA:Ensembl.
DR GO; GO:0070244; P:negative regulation of thymocyte apoptotic process; IEA:Ensembl.
DR GO; GO:0007405; P:neuroblast proliferation; IEA:Ensembl.
DR GO; GO:0046587; P:positive regulation of calcium-dependent cell-cell adhesion; IEA:Ensembl.
DR GO; GO:0008104; P:protein localization; IEA:Ensembl.
DR GO; GO:0070242; P:thymocyte apoptotic process; IEA:Ensembl.
DR Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 1.
DR InterPro; IPR011989; ARM-like.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR000225; Armadillo.
DR InterPro; IPR008658; KAP3.
DR PANTHER; PTHR15605:SF2; KINESIN-ASSOCIATED PROTEIN 3; 1.
DR PANTHER; PTHR15605; KINESIN-ASSOCIATED PROTEINS; 1.
DR Pfam; PF05804; KAP; 1.
DR SMART; SM00185; ARM; 3.
DR SMART; SM01297; KAP; 1.
DR SUPFAM; SSF48371; ARM repeat; 1.
DR PROSITE; PS50176; ARM_REPEAT; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000233180};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..22
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 23..789
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5014348964"
FT REPEAT 586..630
FT /note="ARM"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00259"
FT REGION 110..131
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 110..130
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 789 AA; 90877 MW; 6FFE040E593DA8A3 CRC64;
MATLRVLIWY VISILYYRKV KGGNIDVHPS EKALIVQYEV EATILGEMGD PMLGERKECQ
KIIRLKSLNA NTDITSLARK VVEECKLIHP SKLNEVEQLL YYLQNRRDSL SGKEKKEKSS
KPKDPPPFEG MEIDEVANIN DMDEYIELLY EDIPDKVRGS ALILQLARNP DNLEELLLNE
TALGALARVL REDWKQSVEL ATNIIYIFFC FSSFSQFHGL ITHYKIGALC MNIIDHELKR
HELWQEELSK KKKADILLDC LLDEDPENQT LRKDYEKTFK KYQGLVVKQE QLLRVALYLL
LNLAEDTRTE LKMRNKNIVH MLVKALDRDN FELLILVVEM DIVEKLVKMI PCEHEDLLNI
TLRLLLNLSF DTGLRNKMVQ VGLLPKLTAL LGNDNYKQIA MCVLYHISMD DRFKSMFAYT
DCIPQLMKML FECSDERIDL ELISFCINLA ANKRNVQLIC EGNGLKMLMK RALKFKDPLL
MKMIRNISQH DGPTKNLFID YVGDLAAQIS NDEEEEFVIE CLGTLANLTI PDLDWELVLK
EYKLVPYLKD KLKPGAAEDD LVLEVVIMIG TVSMDDSCAA LLAKSGIIPA LIELLNAQQE
DDEFVCQIIY VFYQMVFHQA TRDVIIKETQ APAYLIDLMH DKNNEIRKVC DNTLDIIAEY
DEEWAKKIQS EKFRWHNSQW LEMVESRQMD ESEQYLYGDD RIEPYIHEGD ILERPDLFYN
SDGLIASEGA ISPDFFNDYH LQNGDVVGQH SFPGSLGMDG FGQPVGILGR PATAYGFRPD
EPYYYGYGS
//
