ID A0A2K6KX07_RHIBE Unreviewed; 446 AA.
AC A0A2K6KX07;
DT 28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT 28-MAR-2018, sequence version 1.
DT 24-JAN-2024, entry version 21.
DE SubName: Full=Growth factor receptor bound protein 7 {ECO:0000313|Ensembl:ENSRBIP00000015806.1};
GN Name=GRB7 {ECO:0000313|Ensembl:ENSRBIP00000015806.1};
OS Rhinopithecus bieti (Black snub-nosed monkey) (Pygathrix bieti).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Cercopithecidae; Colobinae; Rhinopithecus.
OX NCBI_TaxID=61621 {ECO:0000313|Ensembl:ENSRBIP00000015806.1, ECO:0000313|Proteomes:UP000233180};
RN [1] {ECO:0000313|Ensembl:ENSRBIP00000015806.1, ECO:0000313|Proteomes:UP000233180}
RP NUCLEOTIDE SEQUENCE.
RA Wu, C.-I. and Zhang, Y.;
RT "Genome of Rhinopithecus bieti.";
RL Submitted (JUN-2016) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSRBIP00000015806.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
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DR AlphaFoldDB; A0A2K6KX07; -.
DR Ensembl; ENSRBIT00000039650.1; ENSRBIP00000015806.1; ENSRBIG00000031976.1.
DR GeneTree; ENSGT00940000158710; -.
DR Proteomes; UP000233180; Unplaced.
DR GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR CDD; cd01259; PH_APBB1IP; 1.
DR CDD; cd16140; RA_GRB7; 1.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR InterPro; IPR015042; BPS-dom.
DR InterPro; IPR039664; GRB/APBB1IP.
DR InterPro; IPR046986; GRB7_RA.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR039665; PH_APBB1IP.
DR InterPro; IPR001849; PH_domain.
DR InterPro; IPR000159; RA_dom.
DR InterPro; IPR029071; Ubiquitin-like_domsf.
DR PANTHER; PTHR11243; GROWTH FACTOR RECEPTOR-BOUND PROTEIN; 1.
DR PANTHER; PTHR11243:SF25; GROWTH FACTOR RECEPTOR-BOUND PROTEIN 7; 1.
DR Pfam; PF08947; BPS; 1.
DR Pfam; PF00169; PH; 1.
DR Pfam; PF00788; RA; 1.
DR SMART; SM00233; PH; 1.
DR SMART; SM00314; RA; 1.
DR SUPFAM; SSF50729; PH domain-like; 1.
DR SUPFAM; SSF54236; Ubiquitin-like; 1.
DR PROSITE; PS50003; PH_DOMAIN; 1.
DR PROSITE; PS50200; RA; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000233180}.
FT DOMAIN 99..185
FT /note="Ras-associating"
FT /evidence="ECO:0000259|PROSITE:PS50200"
FT DOMAIN 228..337
FT /note="PH"
FT /evidence="ECO:0000259|PROSITE:PS50003"
FT REGION 1..79
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 18..33
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 446 AA; 49324 MW; 3E911DF521FEC6EE CRC64;
MELDLSPPHL GSSPEDLCPA PGTPPGTPRP PDTPLPEEVK RSQPLLIPTT SRKLREEERR
ATSLPSIPNP FPELCSPPSQ SPILGGPSSA RLLPRDASCP HVVKVYSEDG ACRSVEVAAG
ATARHVCEML VQRAHALSDE TWGLVECHPH LALERGLEDH ESVVEVQAAW PVGGDSRFVF
RKNFAKYELF KSSPHSLFPE KMVSSCLDAH TGISHEDLIQ NFLNAGSFPE IQGFLQLRGS
GRKLWKRFFC FLRRSGLYYS TKGTSKDPRH LQYVADVNES NVYVVTQGRK LYGMPTDFGF
CVKPNKLRNG HKGLRIFCSE DEQSRTCWLA AFRLFKYGVQ LYRNYQQAQS CHLRPPCLGS
PPLRSVSDNT LVAMDFSGHA GRVIENPREA LSVALEEAHA WRKKTNHRLS LPTPASGTSL
SAACSWSGRV SGTPRALSSL CATCRK
//
