ID A0A2K6KYZ7_RHIBE Unreviewed; 497 AA.
AC A0A2K6KYZ7;
DT 28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT 28-MAR-2018, sequence version 1.
DT 27-MAR-2024, entry version 32.
DE SubName: Full=Bridging integrator 1 {ECO:0000313|Ensembl:ENSRBIP00000016499.1};
GN Name=BIN1 {ECO:0000313|Ensembl:ENSRBIP00000016499.1};
OS Rhinopithecus bieti (Black snub-nosed monkey) (Pygathrix bieti).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Cercopithecidae; Colobinae; Rhinopithecus.
OX NCBI_TaxID=61621 {ECO:0000313|Ensembl:ENSRBIP00000016499.1, ECO:0000313|Proteomes:UP000233180};
RN [1] {ECO:0000313|Ensembl:ENSRBIP00000016499.1, ECO:0000313|Proteomes:UP000233180}
RP NUCLEOTIDE SEQUENCE.
RA Wu, C.-I. and Zhang, Y.;
RT "Genome of Rhinopithecus bieti.";
RL Submitted (JUN-2016) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSRBIP00000016499.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR RefSeq; XP_017732813.1; XM_017877324.1.
DR AlphaFoldDB; A0A2K6KYZ7; -.
DR Ensembl; ENSRBIT00000040347.1; ENSRBIP00000016499.1; ENSRBIG00000031513.1.
DR GeneID; 108532998; -.
DR CTD; 274; -.
DR GeneTree; ENSGT00950000182882; -.
DR OMA; QEYDYYN; -.
DR OrthoDB; 4243832at2759; -.
DR Proteomes; UP000233180; Unplaced.
DR GO; GO:0005737; C:cytoplasm; IEA:InterPro.
DR GO; GO:0043226; C:organelle; IEA:UniProt.
DR GO; GO:0030100; P:regulation of endocytosis; IEA:InterPro.
DR CDD; cd07611; BAR_Amphiphysin_I_II; 1.
DR CDD; cd12139; SH3_Bin1; 1.
DR Gene3D; 1.20.1270.60; Arfaptin homology (AH) domain/BAR domain; 1.
DR Gene3D; 2.30.30.40; SH3 Domains; 1.
DR InterPro; IPR027267; AH/BAR_dom_sf.
DR InterPro; IPR003005; Amphiphysin.
DR InterPro; IPR035471; Amphiphysin-2_SH3.
DR InterPro; IPR003023; Amphiphysin_2.
DR InterPro; IPR004148; BAR_dom.
DR InterPro; IPR036028; SH3-like_dom_sf.
DR InterPro; IPR001452; SH3_domain.
DR PANTHER; PTHR46514; AMPHIPHYSIN; 1.
DR PANTHER; PTHR46514:SF4; MYC BOX-DEPENDENT-INTERACTING PROTEIN 1; 1.
DR Pfam; PF03114; BAR; 1.
DR Pfam; PF14604; SH3_9; 1.
DR PRINTS; PR01251; AMPHIPHYSIN.
DR PRINTS; PR01253; AMPHIPHYSIN2.
DR PRINTS; PR00452; SH3DOMAIN.
DR SMART; SM00721; BAR; 1.
DR SMART; SM00326; SH3; 1.
DR SUPFAM; SSF103657; BAR/IMD domain-like; 1.
DR SUPFAM; SSF50044; SH3-domain; 1.
DR PROSITE; PS51021; BAR; 1.
DR PROSITE; PS50002; SH3; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000233180};
KW SH3 domain {ECO:0000256|ARBA:ARBA00022443, ECO:0000256|PROSITE-
KW ProRule:PRU00192}.
FT DOMAIN 29..245
FT /note="BAR"
FT /evidence="ECO:0000259|PROSITE:PS51021"
FT DOMAIN 424..497
FT /note="SH3"
FT /evidence="ECO:0000259|PROSITE:PS50002"
FT REGION 246..338
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 357..393
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 157..191
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 497 AA; 55008 MW; 8B398ECBDB9172A6 CRC64;
MAEMGSKGVT AGKIASNVQK KLTRAQEKVL QKLGKADETK DEQFEQCVQN FNKQLTEGTR
LQKDLRTYLA SVKAMHEASK KLNECLQEVY EPDWPGRDEA NKIAENNDLL WMDYHQKLVD
QALLTMDTYL GQFPDIKSRI AKRGRKLVDY DSARHHYESL QTAKKKDEAK IAKAEEELIK
AQKVFEEMNV DLQEELPSLW NSRVGFYVNT FQSIAGLEEN FHKEMSKLNQ NLNDVLVSLE
KQHGSNTFTV KAQPRKKSKL FSRLRRKKNS DNAPAKGNKS PSPPDGSPAA TPEIRVNHEP
EPAGGATPGA TLPKSPSQLR KGPPVPPPPK HTPSKEVKQE QILSLFEDTF VPEISVTTPS
QPAEASEVAG GTQPAAGAQE PGETAASEAT SSSLPAVVVE TFPATVNGTV EGGSGAGRLD
LPPGFMFKVQ AQHDYTATDT DELQLKAGDV VLVIPFQNPE EQDEGWLMGV KESDWNQHKE
LEKCRGVFPE NFTERVP
//
