ID A0A2K6L126_RHIBE Unreviewed; 576 AA.
AC A0A2K6L126;
DT 28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT 28-MAR-2018, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE SubName: Full=Zinc finger protein X-linked {ECO:0000313|Ensembl:ENSRBIP00000017220.1};
GN Name=ZFX {ECO:0000313|Ensembl:ENSRBIP00000017220.1};
OS Rhinopithecus bieti (Black snub-nosed monkey) (Pygathrix bieti).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Cercopithecidae; Colobinae; Rhinopithecus.
OX NCBI_TaxID=61621 {ECO:0000313|Ensembl:ENSRBIP00000017220.1, ECO:0000313|Proteomes:UP000233180};
RN [1] {ECO:0000313|Ensembl:ENSRBIP00000017220.1, ECO:0000313|Proteomes:UP000233180}
RP NUCLEOTIDE SEQUENCE.
RA Wu, C.-I. and Zhang, Y.;
RT "Genome of Rhinopithecus bieti.";
RL Submitted (JUN-2016) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSRBIP00000017220.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the krueppel C2H2-type zinc-finger protein
CC family. {ECO:0000256|ARBA:ARBA00006991}.
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DR AlphaFoldDB; A0A2K6L126; -.
DR STRING; 61621.ENSRBIP00000017220; -.
DR Ensembl; ENSRBIT00000041073.1; ENSRBIP00000017220.1; ENSRBIG00000032622.1.
DR GeneTree; ENSGT00940000158684; -.
DR OMA; SFMPIAW; -.
DR Proteomes; UP000233180; Unplaced.
DR GO; GO:0000785; C:chromatin; IEA:Ensembl.
DR GO; GO:0005730; C:nucleolus; IEA:Ensembl.
DR GO; GO:0005654; C:nucleoplasm; IEA:Ensembl.
DR GO; GO:0001228; F:DNA-binding transcription activator activity, RNA polymerase II-specific; IEA:Ensembl.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0000978; F:RNA polymerase II cis-regulatory region sequence-specific DNA binding; IEA:Ensembl.
DR Gene3D; 3.30.160.60; Classic Zinc Finger; 8.
DR InterPro; IPR006794; Transcrp_activ_Zfx/Zfy-dom.
DR InterPro; IPR036236; Znf_C2H2_sf.
DR InterPro; IPR013087; Znf_C2H2_type.
DR PANTHER; PTHR24393:SF15; IP01201P-RELATED; 1.
DR PANTHER; PTHR24393; ZINC FINGER PROTEIN; 1.
DR Pfam; PF00096; zf-C2H2; 7.
DR Pfam; PF13909; zf-H2C2_5; 1.
DR Pfam; PF04704; Zfx_Zfy_act; 1.
DR SMART; SM00355; ZnF_C2H2; 13.
DR SUPFAM; SSF57667; beta-beta-alpha zinc fingers; 7.
DR PROSITE; PS00028; ZINC_FINGER_C2H2_1; 7.
DR PROSITE; PS50157; ZINC_FINGER_C2H2_2; 13.
PE 3: Inferred from homology;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000233180};
KW Zinc {ECO:0000256|PROSITE-ProRule:PRU00042};
KW Zinc-finger {ECO:0000256|PROSITE-ProRule:PRU00042}.
FT DOMAIN 196..226
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 227..249
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 259..286
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 290..318
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 319..346
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 347..375
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 376..403
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 404..432
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 433..460
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 461..489
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 490..517
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 518..546
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 547..574
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
SQ SEQUENCE 576 AA; 66092 MW; 0911310D1A700DE0 CRC64;
MTMDTESEID PCKVDGTCPE VIKVYIFKAD PGEDDLGGTV DIVESEPEND HGVELLDQNS
SIRVPREKMV YMTVNDSQPE DEDLNVAEIA DEVYMEVIVG EEDAAAAAAA AAVHEQQMDD
NEIKTFMPIA WAAAYGNNSD GIENRNGTAS ALLHIDESAG LGRLAKQKPK KRRRPDSRQY
QTAIIIGPDG HPLTVYPCMI CGKKFKSRGF LKRHMKNHPE HLAKKKYRCT DCDYTTNKKI
SLHNHLESHK LTSKAEKAIE CDECGKHFSH AGALFTHKMV HKEKGANKMH KCKFCEYETA
EQGLLNRHLL AVHSKNFPHI CVECGKGFRH PSELKKHMRI HTGEKPYQCQ YCEYRSADSS
NLKTHVKTKH SKEMPFKCDI CLLTFSDTKE VQQHALIHQE SKTHQCLHCD HKSSNSSDLK
RHIISVHTKD YPHKCDMCDK GFHRPSELKK HVAAHKGKKM HQCRHCDFKI ADPFVLSRHI
LSVHTKDLPF RCKRCRKGFR QQNELKKHMK THSGRKVYQC EYCEYSTTDA SGFKRHVISI
HTKDYPHRCE YCKKGFRRPS EKNQHIMRHH KEVGLP
//
