ID   A0A2K6L1I7_RHIBE        Unreviewed;       679 AA.
AC   A0A2K6L1I7;
DT   28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT   28-MAR-2018, sequence version 1.
DT   24-JAN-2024, entry version 30.
DE   SubName: Full=Forkhead box P4 {ECO:0000313|Ensembl:ENSRBIP00000017388.1};
GN   Name=FOXP4 {ECO:0000313|Ensembl:ENSRBIP00000017388.1};
OS   Rhinopithecus bieti (Black snub-nosed monkey) (Pygathrix bieti).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC   Cercopithecidae; Colobinae; Rhinopithecus.
OX   NCBI_TaxID=61621 {ECO:0000313|Ensembl:ENSRBIP00000017388.1, ECO:0000313|Proteomes:UP000233180};
RN   [1] {ECO:0000313|Ensembl:ENSRBIP00000017388.1, ECO:0000313|Proteomes:UP000233180}
RP   NUCLEOTIDE SEQUENCE.
RA   Wu, C.-I. and Zhang, Y.;
RT   "Genome of Rhinopithecus bieti.";
RL   Submitted (JUN-2016) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Ensembl:ENSRBIP00000017388.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123,
CC       ECO:0000256|PROSITE-ProRule:PRU00089}.
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DR   AlphaFoldDB; A0A2K6L1I7; -.
DR   STRING; 61621.ENSRBIP00000017388; -.
DR   Ensembl; ENSRBIT00000041242.1; ENSRBIP00000017388.1; ENSRBIG00000032681.1.
DR   GeneTree; ENSGT00940000158700; -.
DR   Proteomes; UP000233180; Unplaced.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   CDD; cd20067; FH_FOXP4; 1.
DR   Gene3D; 1.20.5.340; -; 1.
DR   Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR   InterPro; IPR047414; FH_FOXP4.
DR   InterPro; IPR001766; Fork_head_dom.
DR   InterPro; IPR032354; FOXP-CC.
DR   InterPro; IPR030456; TF_fork_head_CS_2.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   PANTHER; PTHR45796; FORKHEAD BOX P, ISOFORM C; 1.
DR   PANTHER; PTHR45796:SF7; FORKHEAD BOX PROTEIN P4; 1.
DR   Pfam; PF00250; Forkhead; 1.
DR   Pfam; PF16159; FOXP-CC; 1.
DR   PRINTS; PR00053; FORKHEAD.
DR   SMART; SM00339; FH; 1.
DR   SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR   PROSITE; PS00658; FORK_HEAD_2; 1.
DR   PROSITE; PS50039; FORK_HEAD_3; 1.
PE   4: Predicted;
KW   DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|PROSITE-
KW   ProRule:PRU00089}; Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW   Nucleus {ECO:0000256|PROSITE-ProRule:PRU00089};
KW   Reference proteome {ECO:0000313|Proteomes:UP000233180};
KW   Repressor {ECO:0000256|ARBA:ARBA00022491};
KW   Zinc {ECO:0000256|ARBA:ARBA00022833};
KW   Zinc-finger {ECO:0000256|ARBA:ARBA00022771}.
FT   DOMAIN          466..539
FT                   /note="Fork-head"
FT                   /evidence="ECO:0000259|PROSITE:PS50039"
FT   DNA_BIND        466..539
FT                   /note="Fork-head"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00089"
FT   REGION          1..56
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          261..305
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          406..445
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          601..679
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        273..287
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   679 AA;  72804 MW;  9C53B6997B68CAF3 CRC64;
     MMVESASETI RSAPSGQNGV GSLSGQTDGS SGGATGTTAS GTGRDMTTGA DSNGEMSPAE
     LLHFQQQQAL QVARQFLLQQ ASGLSSPGNN DSKQSASAVQ VPVSVAMMSP QMLTPQQMQQ
     ILSPPQLQAL LQQQQALMLQ QGVAAGWGPD GMPEADGTPL CPPPRAPHQA LGNKQLAFQQ
     QLLQMQQLQQ QHLLNLQRQG LVSLQPNQAS GPLQTLPQAA VCPTDLPQLW KGEGAPGQPA
     EDSVKQEGLD LTGTAATATS FAAPPKVSPP LSHHTLPNGQ PTVLTSRRDS SSHEETPGSH
     PLYGHGECKW PGCETLCEDL GQFIKHLNTE HALDDRSTAQ CRVQMQVVQQ LEIQLAKESE
     RLQAMMAHLH MRPSEPKPFS QPLNPVPGSS SFSKVTVSAA DSFPDGLVHP PTSAAAPVTP
     LRPPGLGSAS LHGGGPARRR SSDKFCSPIS SELAQNHEFY KNADVRPPFT YASLIRQAIL
     ETPDRQLTLN EIYNWFTRMF AYFRRNTATW KNAVRHNLSL HKCFVRVENV KGAVWTVDER
     EYQKRRPPKM TGSPTLVKNM ISGLSYGALN ASYQAALAES SFPLLNSPGM LNPGSASSLL
     PLSHDDVGAP VEPLPSNGSS SPPRLSPPQY SHQVHVKEEP AEAEEDRQPG PPLGAPNPSA
     SGPPEDRDLE EELPGEELS
//